Alpha Fetoprotein
Alpha - Fetoprotein expression in Hepatocellular Carcinoma.
... - fetoprotein is detected from the very onset of liver formation, produced by all hepatocytes in the liver bud, and continues to be expressed in mice and rats up to delivery and in human fetuses up to the second ...
75
Alpha-fetoprotein-producing rectal cancer successfully responded to preoperative chemoradiotherapy: case report
... Alpha-fetoprotein (AFP) is an oncofetal glycoprotein produced from fetal liver cells, yolk sac cells, and in small quantity from fetal gastrointestinal epithelial cells [1]. In some tumors, such as ...
5
Feasibility studies for assaying alpha-fetoprotein using antibody-activated magnetic nanoparticles
... Abstract: Some previous reports have already shown the characterizations of immunomagnetic reduction (IMR). The assay technology involves the utilities of biofunctionalized magnetic nanoparticles to label target ...
6
Potential of ramucirumab in treating hepatocellular carcinoma patients with elevated baseline alpha-fetoprotein
... Abstract: Hepatocellular carcinoma (HCC) represents ~90% of primary liver cancers and constitutes a major global health problem. Since a decade ago, the management of advanced disease that cannot be locally treated has ...
8
Osteopontin versus alpha-fetoprotein as a diagnostic marker for hepatocellular carcinoma: a meta-analysis
... Methods: Studies that investigated the diagnostic value of OPN and alpha-fetoprotein (AFP) in HCC were collected from PubMed and Embase. Sensitivity, specificity, and other parameters about the diagnostic ...
11
Alpha fetoprotein DNA prime and adenovirus boost immunization of two hepatocellular cancer patients
... 24. Kantoff PW, Schuetz TJ, Blumenstein BA, Glode LM, Bilhartz DL, Wyand M, Manson K, Panicali DL, Laus R, Schlom J, Dahut WL, Arlen PM, Gulley JL, Godfrey WR: Overall survival analysis of a phase II randomized ...
9
Alpha fetoprotein antagonises benzyl isothiocyanate inhibition of the malignant behaviors of hepatocellular carcinoma cells
... cells. Alpha-fetoprotein (AFP) is a important molecule for promoting progression of HCC, in the present investigation, we explore the influence of AFP on the role of BITC in the malignant behaviours of HCC ...
14
Maternal serum alpha fetoprotein levels in fetal hydrocephalus: a retrospective population based study
... fluid alpha-fetoprotein levels that they observed in four cases of fetal hydrocephalus might be due to pas- sage of AFP-containing cerebral spinal fluid across the greatly thinned fetal skull into the ...
5
Identification of pregnancy-associated glycoproteins and alpha-fetoprotein in fallow deer (Dama dama) placenta
... raised against a boPAG-2 preparation [33-35]. Western blot analysis highlighted immunoreactivity of several pro- teins issued from Sepharose 4B Ig-438 affinity chromatog- raphy with both R#435 and R#706. This ...
11
Association between alpha-fetoprotein and metabolic syndrome in a Chinese asymptomatic population: a cross-sectional study
... Alpha-fetoprotein (AFP) is a single-stranded glycopro- tein primarily produced by the fetal liver and yolk sac. The level of AFP declines rapidly after birth and remains at a low level throughout the life ...
9
The relationship between second trimester alpha fetoprotein levels and adverse pregnancy outcome
... Our study shows there is a highly significant associa- tion between elevated maternal serum alpha-fetoprotein levels (in this study the “normal” cut off defined as 2.0 MoM) and each of the adverse pregnancy ...
5
Diagnostic and mechanistic implications of serum free light chains, albumin and alpha-fetoprotein in hepatocellular carcinoma
... serum alpha-fetoprotein (AFP) has been widely used in this respect and indeed it is well recognised to be highly specific and useful in the clinical setting when levels are elevated above a particular ...
6
Fluorescence Quenching of Alpha Fetoprotein by Gold Nanoparticles: Effect of Dielectric Shell on Non Radiative Decay
... [11]. Alpha-fetoprotein (AFP) is an oncofetal protein, which has been widely used as a tumor marker for diagnosis and management of hepatocellular carcinoma ...
6
Serum vitamin D binding protein is a third member of the albumin and alpha fetoprotein gene family
... isolated from a human liver mRNA expression library. Complete sequence analysis of this clone predicts the full-length amino acid sequence of the pre-hDBP. Comparison of the sequence of the hDBP mRNA and protein to ...
6
HBV associated intrahepatic cholangiocarcinoma with high serum alpha fetoprotein: a case report with review of literature
... AFP, alpha- fetoprotein; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CA125, carbohydrate antigen 125; CA19-9, carbohydrate antigen 19-9; CEA, carcinoembryonic antigen; CT, computed ...
6
Case Report Alpha-fetoprotein-producing hepatoid adenocarcinoma of the gallbladder: a case report and review of literature
... Abstract: Hepatoid adenocarcinoma (HAC) is an uncommon type of malignancy in extrahepatic tissues. It was named for its histopathological resemblance of hepatocellular carcinoma, the most common form of liver cancer. The ...
6
Original Article Clinicopathological characteristics and prognosis of alpha-fetoprotein positive gastric cancer in Chinese patients
... Abstract: Purpose: This study aimed to review the clinicopathological, histochemical, and prognostic features of Alpha-Fetoprotein (AFP) positive gastric cancer. Patients and methods: Six hundred and fifty ...
11
Characterization of alpha-fetoprotein effects on dendritic cell and its function as effector immune response activator
... Abstract: Tumor antigen alpha-fetoprotein (AFP) can promote immune tolerance toward tumor cells by inducing regulatory functions of the immune system. The purpose of this study was to characterize the ...
13
Sandwich-Type Electrochemiluminescence Immunosensor Based on PDDA-G@Lu-Au Composite for Alpha-Fetoprotein Detection
... separation and purification of signal antibody on magnetic field, but also enhanced the fixed capacity of Ab1 to improve detection range. In addition, the magnetic probes were readily immobilized on the working electrode ...
15
Fabrication of an Electrochemical Immunosensor Containing Au–Ag Alloy for the Detection of Alpha Fetoprotein
... This study presented the enzyme-free determination of alpha fetoprotein (AFP) using a new electrochemical immunosensor. Our proposed immunosensor consisted of a sandwich system involving catalytic Au–Ag ...
9