Alpha-glucosidase (?- glucosidase)
Intravenous administration of phosphorylated acid alpha glucosidase leads to uptake of enzyme in heart and skeletal muscle of mice
... acid alpha-glucosidase by heart and skeletal muscle appeared to be significantly less efficient, whereas uptake of dephosphorylated bovine testes enzyme was not ...acid alpha-glucosidase ...
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Alpha-Glucosidase Inhibitory Activity of Garcinia lateriflora Blume Leaves
... on alpha-glucosidase (Etxeberria et ...of alpha-glucosidase, therefore increasing the number of free phenolic groups will increase the ability to inhibits alpha-glucosidase ...
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Is Alpha Glucosidase Inhibition a Mechanism of the Antidiabetic Action of Garlic (Allium sativum)?
... inhibiting alpha-gluco- sidase. We proposed that inhibition of alpha-glucosidase is the mechanism by which garlic produces its antidiabetic ...
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Alpha Glucosidase Inhibitory Activity of Compounds from Bauhinia strychnifolia
... Alpha-glucosidase inhibition was determined for all extracts according to previously reported assays [8]. This protocol would be described briefly subsequently. After hydrolysis reaction, a substrate such ...
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IN SILICO SCREENING FOR ALPHA GLUCOSIDASE INHIBITORS OF CHROMONE DERIVATIVES
... alpha glucosidase available through the RCSB Protein Data ...of alpha glucosidase order to compare the binding ...for alpha amylase given in the (Table ...
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ALPHA AMYLASE AND ALPHA GLUCOSIDASE INHIBITORY ACTIVITY OF AMALAKI RASAYANA AN AYURVEDIC FORMULATION
... Pancreatic Alpha Amylase and Intestinal Alpha Glucosidase in in vitro ...to alpha amylase and change its activity due to the ability to form quinones or lactones that react with nucleophilic ...
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Clinical diversity in glycogenosis type II Biosynthesis and in situ localization of acid alpha glucosidase in mutant fibroblasts
... associated with transport to the lysosomes. Deficiency of catalytically active mature enzyme in lysosomes is common to all clinical phenotypes but, in the majority of cases, is more profound in early onset than in late ...
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ALPHA-GLUCOSIDASE INHIBITING ACTIVITY OF FIVE MEXICAN PLANTS USED IN THE TREATMENT OF TYPE 2 DIABETES.
... The alpha-glucosidase inhibitors (AGIs) lower postprandial blood glucose concentrations, act as competitive inhibitors and exhibit a high affinity for alpha-glucosidases, blocking the enzymatic ...
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Searching for Alpha-Glucosidase Inhibitory Activity in Hexane Extracts by some Plants from Kurdistan Province
... inhibitor in this study, showed the IC50 of 1.49M. At the concentration of the test samples in the study, acarbose entirely inhibited the activity of alpha-glucosidase. Since IC50 for Descurania Sophia (L.) ...
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Homology Modeling of Human Alpha Glucosidase Catalytic Domains and SAR Study of Salacinol Derivatives
... intestinal alpha-glucosidase and their N-terminal side catalytic domains are called NtMGAM and NtSI, and their C-terminal side catalytic domains are called CtMGAM and ...antidiabetic, ...
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Characterization of the molecular defect in infantile and adult acid alpha glucosidase deficiency fibroblasts
... acid alpha-glucosidase deficiency have been ...Acid alpha-glucosidase (EC ...acid alpha-glucosidase deficiency ...turanose, alpha-methylglucoside and trehalose were the ...
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<p>Comparative Cholinesterase, α-Glucosidase Inhibitory, Antioxidant, Molecular Docking, and Kinetic Studies on Potent Succinimide Derivatives</p>
... Molecular docking was performed using Dock Module implemented in Molecular Operating Environment (MOE) software 49,50 to explore the binding mode of the tested compounds against acetylcholinesterase (AChE), ...
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IN VITRO INHIBITORY EFFECT OF METHANOL, HEXANE AND ETHYLACETATE EXTRACTS OF ALBIZIA LEBBECK (SIRIS TREE) STEM BARK ON THE ACTIVITY OF ALPHA GLUCOSIDASE
... Albizia lebbeck stem bark has inhibitory potential on alpha-glucosidase activity. The hexane extract is the most active solvent extract among the solvents, and the inhibitory effect was concentration ...
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Meta-analysis of the impact of alpha-glucosidase inhibitors on incident diabetes and cardiovascular outcomes
... of alpha-glucosidase inhibitors suggested that they may prevent the progression if carotid intima thickness in patients with IGT or type 2 diabetes, [14] but our CV meta-analysis suggests this does not ...
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Antioxidant and Alpha Glucosidase Inhibition Activity of Kupa (Syzygium Polychepalum Miq.) Cortex
... of alpha glucosidase was carried out by using purified and commercial alpha glucosidase enzymes, a measurement based on methods reported by ...[26]. Alpha glucosidase enzyme of ...
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Alpha Glucosidase inhibitory activity of Morus Alba
... Alpha-glucosidase inhibitors (AGIs; acarbose, voglibose) are widely used in the treatment of patients with type 2 diabetes. Alpha-glucosidase inhibitors are oral antidiabetic drugs. AGIs delay ...
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In-vitro studies on inhibition of alpha amylase and alpha glucosidase by plant extracts of alternanthera Pungens kunth
... the alpha amylase and alpha glucosidase inhibitory activities of ethanolic and aqueous extract of whole plant of Alternanthera Pungens ...both. Alpha amylase and alpha ...
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EVALUATION OF ALPHA – AMYLASE AND ALPHA – GLUCOSIDASE INHIBITORY ACTIVITIES OF RHIZOPHORA MUCRONATA
... inhibited alpha-glucosidase more potently than the standard ...on alpha-amylase ...of alpha- glucosidase enzyme, but no inhibitory activity on alpha-amylase enzyme by clonal ...
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Potent Natural Inhibitors of Alpha-Glucosidase and Alpha-Amylase against Hyperglycemia in Vitro and in Vivo
... the alpha-glucosidase to support this traditional use of berberine and Chinese Goldthread Rhizome for the treatment of diabetes ...inhibit alpha-glucosidase and decrease glucose transport ...
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In vitro anti-diabetic activity of flavonoids and pheophytins from Allophylus cominia Sw . on PTP1B, DPPIV, alpha-glucosidase and alpha-amylase enzymes
... The ability of DPPIV inhibitors to improve glucose control in T2-DM, has led to the examination of natural products with DPPIV inhibitory properties (Mardanyan et al., 2011). This study has shown that a mixture of ...
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