alpha(v)beta(3) integrin
Glioblastoma expression of vitronectin and the alpha v beta 3 integrin Adhesion mechanism for transformed glial cells
... The alpha v beta 3 integrin was the only vitronectin receptor identified in glioblastoma tumors in situ, and was also not expressed on low grade astroglial-derived tumors, ...
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Human melanoma cells derived from lymphatic metastases use integrin alpha v beta 3 to adhere to lymph node vitronectin
... to integrin alpha v beta ...of alpha v beta 3 on the metastatic cells as compared to the parent ...the alpha v beta 3 receptor plays a ...
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Involvement of integrin alpha V gene expression in human melanoma tumorigenicity
... of alpha v integrins on the tumorigenicity of human ...lack alpha v gene expression and thus fail to express integrin alpha v beta 3 (M21-L ...identical ...
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Ligand bridging mediates integrin alpha IIb beta 3 (platelet GPIIB IIIA) dependent homotypic and heterotypic cell cell interactions
... mutant, alpha IIb beta 3 (beta 1-2), indicating that only one of the cells in an interacting pair must be ...activated alpha IIb beta 3 and cells bearing alpha ...
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Treatment of marrow stroma with interferon alpha restores normal beta 1 integrin dependent adhesion of chronic myelogenous leukemia hematopoietic progenitors Role of MIP 1 alpha
... modulating beta 1 integrin receptor ...that alpha 4 beta 1 and alpha 5 beta 1 integrin receptors were involved in the enhanced adhesion of CML progenitors, suggesting that ...
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Vitronectin enhances internalization of crocidolite asbestos by rabbit pleural mesothelial cells via the integrin alpha v beta 5
... internalization via alpha v beta 5, an effect dependent on the vitronectin in serum. We conclude that pleural mesothelial cells recognize and internalize vitronectin- and serum- coated asbestos via ...
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Involvement of ROS alpha v beta 3 integrin FAK/Pyk2 in the inhibitory effect of melatonin on U251 glioma cell migration and invasion under hypoxia
... dimeric integrin molecules mediate various complex processes including angiogenesis in a cell type- and context-dependent manner ...β3 integrin is mainly associated with tumor metastasis, and the αvβ3 ...
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Identification of surface proteins mediating adherence of CD11/CD18 deficient lymphoblastoid cells to cultured human endothelium
... the alpha 4 polypeptide (CD49d) and the beta 1 polypeptide (CD29) of the lymphocyte VLA-4 integrin receptor (CD49d/CD29), and to vascular cell adhesion molecule-1 (VCAM-1) on the endothelial cell ...
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Expression of alpha v beta 5 integrin is necessary for efficient adenovirus-mediated gene transfer in the human airway.
... N,N,N9,N9-tetraacetic acid, pH 8.0] and incubated with an appropriate amount of synthetic peptide or soluble MAb at 48C for 1 h, followed by the addition of lacZ adenovirus (50 PFU per cell) at 48C. After 1 h, the cells ...
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p190RhoGAP is the convergence point of adhesion signals from alpha 5 beta 1 integrin and syndecan-4.
... recombinant integrin ligand (50K) were stimulated with heparin- binding fragments of fi bronectin (H/0) for 60 min before fi xing and staining for vinculin (green) and/ or actin ...5 integrin (mAb16), ...
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Insulin like growth factor receptor cooperates with integrin alpha v beta 5 to promote tumor cell dissemination in vivo
... Cytokine stimulation of CS-1 cell metastasis. To assess the biological significance of avb5-dependent CS-1 cell motility, we examined the growth and spontaneous metastatic proper- ties of these CS-1 cells in the chick ...
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Aberrant integrin expression during epidermal wound healing and in psoriatic epidermis
... hyperproliferative, alpha 2, alpha 3, alpha 6, and beta 1 were no longer confined to the basal layer, as in normal epidermis, but were also found in all the living suprabasal cell ...
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Cellular distribution of transforming growth factor beta 1 and procollagen types I, III, and IV transcripts in carbon tetrachloride induced rat liver fibrosis
... procollagen genes were not detected in hepatocytes throughout the experiment. No significant differences in cellular distribution or time course of gene expression among procollagen alpha 1(I), alpha ...
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The relationship between the impaction of Mandibular Third Molar and Guns Ratio
... angles alpha, beta and Guns ratio was significant but gonial angle (left and right), the difference was not significant ...angles alpha, beta and Guns ratio can predict the effect of impaction ...
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Overexpression of platelet type 12 lipoxygenase promotes tumor cell survival by enhancing alpha(v)beta(3) and alpha(v)beta(5) integrin expression
... The ability of tumors to invade beyond hemostatic boundaries and form metastatic colonies requires the complex interplay of various cell surface-associated components regulating the proteolytic disruption of the ECM and ...
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αVβ3-Integrin Relocalizes nectin1 and Routes Herpes Simplex Virus to Lipid Rafts
... dependent entry rests on redirecting nectin1, or the complex of nec- tin1 plus HSV, to the lipid rafts, from which location the virus is then endocytosed. The hypothesis predicts that engineered forms of nec- tin1 ...
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HIV Integrase Inhibitors Block Replication of Alpha , Beta , and Gammaherpesviruses
... binding to ICP8, and there may have been a slight increase in DNA binding in the presence of XZ45 (Fig. 5C). Second, in an ssDNA- coated-bead pulldown assay, we observed that XZ45 did not in- hibit ICP8 binding to the ...
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Integrin and Defensin Modulate the Mechanical Properties of Adenovirus
... without integrin and complexed with integrin indicate that the penton is inserted in a slightly twisted way in the virion and that integrin binding leads to an untwisting of the penton (8, ...of ...
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EXTRACTION OF ESSENTIAL OIL FROM FLOWERS OF MESUA FERREA LINN GC MS ANALYSIS AND INCORPORATION IN COSMETIC PRODUCT
... components. Alpha-Copaene (13.52%), Trans-Alpha-Bergamotene ...contained Alpha-Copaene (22.72%), Trans- Alpha-Bergamotene ...were Alpha Copaene (28.49%), Beta caryophyllene ...
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A peptidomimetic antagonist of the alpha(v)beta3 integrin inhibits bone resorption in vitro and prevents osteoporosis in vivo
... Human platelet-rich plasma assay. Healthy aspirin-free donors were randomly selected from a pool of volunteers. Harvesting of platelet- rich plasma and subsequent ADP-induced platelet aggregation assays were performed as ...
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