alveolar epithelial cells type 1
Alert cell strategy in SIRS-induced vasculitis: sepsis and endothelial cells
... various epithelial cells and vascular endothelial ...dendritic cells, and the overproduction of inflammatory ...some epithelial cells in major organs express inflammatory receptors on ...
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Mechanisms of lung fibrosis induced by carbon nanotubes: towards an Adverse Outcome Pathway (AOP)
... adenocarcinoma epithelial cell line; AM: alveolar macrophages; AO: adverse outcome; AOP: adverse outcome pathway; ATII: primary human alveolar type-II epithelial cells; BEAS-2B: ...
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Human alveolar epithelial cells type II are capable of TGFβ-dependent epithelial-mesenchymal-transition and collagen-synthesis
... μl 1× Rotiblock solu- tion (Carl Roth, Karlsruhe, Germany) at ...and cells incubated with 50 μl of primary antibodies diluted in 1× Rotiblock over-night at 4 ...and cells washed three times ...
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Differential bioreactivity of neutral, cationic and anionic polystyrene nanoparticles with cells from the human alveolar compartment: robust response of alveolar type 1 epithelial cells
... two cells types (AT2 and MACs) using TEM, an accurate but time consuming technique to quantify the percent of NP ...of cells. One mechanism by which TT1 cells internalise molecules is by endocytosis, ...
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Wnt signaling regulates trans-differentiation of stem cell like type 2 alveolar epithelial cells to type 1 epithelial cells
... for alveolar morphogenesis it is not essential for the development of proximal airways ...alter alveolar epithelial differentiation [18] and can give rise to modified molecular microenvironments that ...
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Proliferative regulation of alveolar epithelial type 2 progenitor cells by human Scnn1d gene
... AT2 cells were isolated from both wt and Scnn1d Tg/Cre strains with C57BL/6 genetic background with a modified protocol of a previous publication [71, ...minutes. Cells were passed through a serial of Nitex ...
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Profibrotic potential of Prominin-1+epithelial progenitor cells in pulmonary fibrosis
... progenitor cells raised serious questions about the safety of stem cell-based therapies against ...of cells isolated from injured organs for cell-based ...derived cells or affect also the function of ...
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Culture of human alveolar epithelial type II cells by sprouting
... lung alveolar epithelium comprises two types of specialized epithelial cells, the alveolar epithelial type I cells (AT1), that cover approximately 93% of the ...
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Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis
... by alveolar epithelial cell injury and hyperplasia, inflammatory cell accumulation, fibrob- last hyperplasia, formation of honeycomb cysts and exu- berant production and deposition of extracellular matrix ...
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The development and plasticity of alveolar type 1 cells
... AT1 cells flatten in conjunction with molecular ...wedge-shaped epithelial progenitors (P) are found in branch tips. Elongated AT1 cells and cuboidal AT2 cells are found in branch stalks and ...
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Case Report Primary pleomorphic adenoma of the lung with positive staining of TTF-1: a case report and review of literature
... tumor epithelial cells were po- sitive for TTF-1 staining. TTF-1 was used as a marker for pulmonary or thyroid epithelial ce- ...pulmonary epithelial cells, such as ...
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Mac-1 deficiency induces respiratory failure by affecting type I alveolar epithelial cells.
... 2011). Alveolar epithelial cells are divided into type I and type II ...stem cells and have the potential to give rise to the former. Moreover, type II cells can ...
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Alveolar Type II Epithelial Cells Contribute to the Anti Influenza A Virus Response in the Lung by Integrating Pathogen and Microenvironment Derived Signals
... and normalized with the Robust Multi-array Analysis (RMA) algorithm. To exclude probe sets with consistently low signal intensities in all mi- croarrays performed, only probe sets with signal intensities above the 20th ...
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PlGF mediates neutrophil elastase-induced airway epithelial cell apoptosis and emphysema
... LE cells [36-39]. The Egr-1-upregulated down-stream genes mediate various cellular functions like cell growth, proliferation, differentiation, and apoptosis ...
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Cigarette Smoke Induces Apoptosis by Activation of Caspase 3 in Isolated Fetal Rat Lung Type II Alveolar Ep ithelial Cells in Vitro
... [9]. Cells undergoing apoptosis show characteris- tic well defined morphologic changes differentiating it from ...dying cells are not released in the surround- ing interstitial ...
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Examining the role of ABC lipid transporters in pulmonary lipid homeostasis and inflammation
... inflammatory cells and media- tors in the lung following atorvastatin treatment, although this did not translate into improved lung function ...in cells negatively affect ABCA1 and ABCG1 expression via an ...
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GABA receptor ameliorates ventilator induced lung injury in rats by improving alveolar fluid clearance
... causes epithelial damage, oxidative stress, surfactant inactivation, and pul- monary edema ...clear alveolar fluid in rats after injurious mechanical venti- lation ...
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Successful Readministration of Adeno-Associated Virus Vectors to the Mouse Lung Requires Transient Immunosuppression during the Initial Exposure
... vascular cells in the MR1- and CTLA4Ig-treated mice and in the RagII-deficient mice in comparison to that of con- trol animals that had not been exposed to an AAV ...
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Original Article Hsa-miR-921 mediates lung injury via IL-37 in a rat model of traumatic hemorrhagic shock
... mononuclear cells (PBMCs), macrophages, and epithelial cells, IL-37 is induced by a variety of pro-inflammatory cyto- kines, such as TNF-α, IL-1β, IL-8, IL-6, IFN-γ, and macrophage inflammatory ...
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Enhanced non vitreous cryopreservation of immortalized and primary cells by ice growth inhibiting polymers
... Primary cells also tend to be less tolerant to environmental perturbations ex ...FAO cells, primary rat hepato- cytes were harvested (sprague dawley) and prepared according standard ( percoll) ...These ...
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