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Alveolar Epithelium

Importin-α7 Is Required for Enhanced Influenza A Virus Replication in the Alveolar Epithelium and Severe Lung Damage in Mice

Importin-α7 Is Required for Enhanced Influenza A Virus Replication in the Alveolar Epithelium and Severe Lung Damage in Mice

... bronchial epithelium. In contrast, the bronchial and alveolar epithelium of WT mice is abundantly infected at a time point where overall virus lung titers do not differ ...chial epithelium of ...

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Predifferentiated amniotic fluid mesenchymal stem cells enhance lung alveolar epithelium regeneration and reverse elastase-induced pulmonary emphysema

Predifferentiated amniotic fluid mesenchymal stem cells enhance lung alveolar epithelium regeneration and reverse elastase-induced pulmonary emphysema

... II alveolar epithelial cells, which are known progenitor cells for alveolar epithelium, also modulates the inflammatory response and alveolar edema fluid ...and alveolar epithelial ...

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Activation of Wnt/β-catenin signalling promotes mesenchymal stem cells to repair injured alveolar epithelium induced by lipopolysaccharide in mice

Activation of Wnt/β-catenin signalling promotes mesenchymal stem cells to repair injured alveolar epithelium induced by lipopolysaccharide in mice

... the alveolar epithelium in ARDS is consid- ered to be a key factor in the leakage of protein-rich oedema fluid into the interstitium and alveolar space ...

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Expression of truncated Int6/eIF3e in mammary alveolar epithelium leads to persistent hyperplasia and tumorigenesis

Expression of truncated Int6/eIF3e in mammary alveolar epithelium leads to persistent hyperplasia and tumorigenesis

... hyperplastic alveolar nodules and ...in alveolar hyperplasia, we targeted Int6sh expres- sion to the differentiating alveolar epithelium using the whey acidic protein (Wap) promoter, which is ...

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Gene expression profiles of human dendritic cells interacting with Aspergillus fumigatus in a bilayer model of the alveolar epithelium/endothelium interface

Gene expression profiles of human dendritic cells interacting with Aspergillus fumigatus in a bilayer model of the alveolar epithelium/endothelium interface

... the alveolar epithelium (Tables 5 and 6) revealed differences in the expression of PTX3 and CCL20 which are important for immune response against ...as alveolar macrophages and neutrophils react to ...

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Human iPS cell–derived alveolar epithelium repopulates lung extracellular matrix

Human iPS cell–derived alveolar epithelium repopulates lung extracellular matrix

... Generating AFE from DE cells. Following developmental para- digms, directed differentiation of iPSCs to alveolar epithelium should proceed by generation of DE, followed by patterning into AFE. ...

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Bench to bedside review: The role of the alveolar epithelium in the resolution of pulmonary edema in acute lung injury

Bench to bedside review: The role of the alveolar epithelium in the resolution of pulmonary edema in acute lung injury

... the alveolar epithelium to such an extent that stimulation of the fluid transport machinery is ...the epithelium through stem cell transplantation would be a possible treatment in the future ...of ...

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Conditional over-expression of RAGE by embryonic alveolar epithelium compromises the respiratory membrane and impairs endothelial cell differentiation

Conditional over-expression of RAGE by embryonic alveolar epithelium compromises the respiratory membrane and impairs endothelial cell differentiation

... involving alveolar epithelium allowed for the assessment of RAGE over- expression on the respiratory membrane that is comprised of alveolar epithelium, endothelium, and a fused basement ...

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Protein permeability in the adult respiratory distress syndrome  Loss of size selectivity of the alveolar epithelium

Protein permeability in the adult respiratory distress syndrome Loss of size selectivity of the alveolar epithelium

... edema fluid. The relationship of distribution coefficient vs. log molecular weight for seven proteins (54,000-900,000 mol wt) hyperbolically increased in normals but was flat in ARDS patients. Sodium dodecyl ...

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Voltage-gated proton channels help regulate pH in rat alveolar epithelium

Voltage-gated proton channels help regulate pH in rat alveolar epithelium

... 34. Peers C, Kemp PJ, Boyd CAR, and Nye PCG. Whole-cell K ⫹ currents in type II pneumocytes freshly isolated from rat lung: pharmacological evidence for two subpopulations of cells. Biochim Biophys Acta 1052: 113–118, ...

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Deuterium Isotope Effects on Permeation and Gating of Proton Channels in Rat Alveolar Epithelium

Deuterium Isotope Effects on Permeation and Gating of Proton Channels in Rat Alveolar Epithelium

... II alveolar epithelial cells were isolated from adult male Sprague-Dawley rats under sodium pentobarbital anesthesia us- ing enzyme digestion, lectin agglutination, and differential ad- herence, as described in ...

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3. Respiratory physiology (Lec 3).ppt

3. Respiratory physiology (Lec 3).ppt

...  Oxygen and carbon dioxide diffuse across easily alveolar epithelium capillary endothelium fused basement membranes of both epithelial tissues... Composition of respiratory membrane.[r] ...

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Hypercapnic acidosis attenuates pulmonary epithelial stretch-induced injury via inhibition of the canonical NF-κB pathway

Hypercapnic acidosis attenuates pulmonary epithelial stretch-induced injury via inhibition of the canonical NF-κB pathway

... Our findings confirm the deleterious effects of prolonged excessive cell stretch on the alveolar epithelium. Positive pressure ventilation can severely injure the lungs of already compromised ARDS patients, ...

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WNT signaling – lung cancer is no exception

WNT signaling – lung cancer is no exception

... primordial epithelium (PE), alveolar epithelium (AE), and adjacent mesenchyme ...peripheral epithelium, LEF1 expression is detected in alveolar and bronchial epithelium, while ...

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Divergent expression of claudin -1, -3, -4, -5 and -7 in developing human lung

Divergent expression of claudin -1, -3, -4, -5 and -7 in developing human lung

... The epithelium becomes ...the epithelium of bronchi and bronchioles, whereas alveolar epithelium was negative (Fig ...in alveolar epithelium ...in epithelium of bronchi ...

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Matrilysin expression and function in airway epithelium

Matrilysin expression and function in airway epithelium

... the epithelium of peribronchial glands and conducting airways in normal ...in alveolar type II cells in cystic ...lung epithelium, but upon activation or while migrating over wounds, some matrilysin ...

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HIV-1 transgene expression in rats causes oxidant stress and alveolar epithelial barrier dysfunction

HIV-1 transgene expression in rats causes oxidant stress and alveolar epithelial barrier dysfunction

... the alveolar epithelial barrier was impaired, with decreased lung liq- uid clearance in vivo that correlated with increased para- cellular permeability of alveolar epithelial monolayers in ...the ...

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Endothelial mitochondria determine rapid barrier failure in chemical lung injury

Endothelial mitochondria determine rapid barrier failure in chemical lung injury

... from alveolar HCl–initiated H 2 O 2 diffu- sion from the alveolar epithelium, we transfected the alveolar epithelium with ...catalase-transfected alveolar epithelium, ...

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Hypothesis: do voltage-gated H channels in alveolar epithelial cells contribute to CO 2elimination by the lung?

Hypothesis: do voltage-gated H channels in alveolar epithelial cells contribute to CO 2elimination by the lung?

... the alveolar transepithelial PD is complicated greatly by tissue ...the alveolar PD, the observed value in a fluid-filled lung can be dominated by that across the airways ...the alveolar PD might be ...

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Cellular and acellular ex vivo lung perfusion preserve functional lung ultrastructure in a large animal model: a stereological study

Cellular and acellular ex vivo lung perfusion preserve functional lung ultrastructure in a large animal model: a stereological study

... than alveolar air pressure during inflation (aEVLP ...exceeded alveolar air pressure in both EVLP groups (aEVLP ...of alveolar epithelium in oedema covered areas as a morphological ...

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