alveolar type I/II cells
Culture of human alveolar epithelial type II cells by sprouting
... epithelial cells from two different donors were used ...The cells were lysed with Pierce IP lysis buffer (Thermo Fischer Scientific, Waltham, MA, USA) according to the manufacturer’s ...
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Human alveolar epithelial cells type II are capable of TGFβ-dependent epithelial-mesenchymal-transition and collagen-synthesis
... module I pointed towards processes which are constituted by elevated actin and filament ...of cells during EMT [12, 15, 22], was assessed on protein level to validate the results from the gene expression ...
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Alveolar Type II Epithelial Cells Contribute to the Anti Influenza A Virus Response in the Lung by Integrating Pathogen and Microenvironment Derived Signals
... IFN I production have been described in TLR7ko mice (19, 39), it was surprising that TLR7 played such a central role in ensuring a robust early IFN response in our ...IFN I/III in the respiratory tract of ...
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Exosome miR-371b-5p promotes proliferation of lung alveolar progenitor type II cells by using PTEN to orchestrate the PI3K/Akt signaling
... that of its mouse homolog. As shown in Fig. 5e, miR-371b- 5p and its mouse homologous miR-292b-5p do share ap- proximately 91% sequence homology. For clarification, we designed two reverse primers, R-primer-I and ...
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Mechanisms of lung fibrosis induced by carbon nanotubes: towards an Adverse Outcome Pathway (AOP)
... adenocarcinoma alveolar epithelial cell line; ATII: primary human alveolar type-II epithelial cells; BALB-3 T3: mouse embryonic fibroblast cell line; BEAS-2B: human bronchial epithelial ...
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Induced pluripotent stem cell-derived lung alveolar epithelial type II cells reduce damage in bleomycin-induced lung fibrosis
... Although our protocol for cell differentiation from iPSC into AEC2 has been effective with high efficiency, it is important to develop further a protocol where the differentiation will be fully efficient. Our iPSC ...
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Endothelial-monocyte activating polypeptide II disrupts alveolar epithelial type II to type I cell transdifferentiation
... ATII cells from disso- ciated rat lungs were subjected to IgG panning and determined to be 85-90% pure by lamellar body expres- sion (P180, Figure 1A), were plated on polycarbonate fil- ters in serum-free ...
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LysoTracker is a marker of differentiated alveolar type II cells
... epithelial cells with lung mesenchymal stromal cells in the lung epithelial colony-forming unit assay (CFU-Epi) assay stimulates the proliferation and differentiation of lung epithelial progenitor ...
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Original Article Hyperbaric oxygen treatment reduced the lung injury of type II decompression sickness
... with type II decompression sickness (DCS), and study the therapeutic effects of hyperbaric oxygen ...blood cells in the alveolar space. Type I alveolar epithelial ...
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Mac-1 deficiency induces respiratory failure by affecting type I alveolar epithelial cells.
... Type I alveolar epithelial cells cover more than 95% of the alveolar surface, and are vulnerable to various ...These cells are distinct from type II alveolar ...
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Regeneration of the lung: Lung stem cells and the development of lung mimicking devices
... AT-II cells already demonstrated that AT-II cells can differentiate into AT-I cells ...AT-I cells after pneumonectomy has been ...AT-I cells ...
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PlGF mediates neutrophil elastase-induced airway epithelial cell apoptosis and emphysema
... LE cells results in the loss of lung paren- chyma and is a potential pathogenic mechanism for em- physema and COPD ...of type II alveolar epithelial cells (AEC II) such that PlGF ...
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rcmb.2017-0019oc.pdf
... T cells, has also been shown to express kgf in the skin and intestine (21, ...epithelial cells, as previously described (19, ...by alveolar macrophages and increased bronchoalveolar lavage (BAL) ...
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Effects of Perfluorocarbons on surfactant exocytosis and membrane properties in isolated alveolar type II cells
... with cells is required to show effects. For ATP and PMA treated cells, the stimulatory effect of PFC may even not be accomplished to a full extent after this ...
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Expression of Respiratory Syncytial Virus-Induced Chemokine Gene Networks in Lower Airway Epithelial Cells Revealed by cDNA Microarrays
... ible members of the chemokine superfamily by hierarchical clustering and PCA and have consistently observed three subgroups whose members are linked by their expression pat- terns. We note that members of the most highly ...
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Alveolar type II epithelial cells produce interleukin 6 in vitro and in vivo Regulation by alveolar macrophage secretory products
... Induction was abolished when CM were preincubated with anti-IL-1 beta and anti-TNF alpha antibody. The combination of IFN gamma and LPS induced the expression of IL-6 mRNA by A549 cells whereas LPS alone had no ...
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Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis
... genic mice were found to develop early perivascular and peribronchial lymphohistiocytic infiltrates with signifi- cantly increased lung fibrosis developing in the wild-type but not cath K tg mice (Figure 5). At ...
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Alert cell strategy in SIRS-induced vasculitis: sepsis and endothelial cells
... alert cells [12, 25], these cells also increase in number due to SIRS complica- tion or sustained ...Alert cells express inflam- matory receptors on their surface and in their cytoplasm and are ...
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Case Report Primary pleomorphic adenoma of the lung with positive staining of TTF-1: a case report and review of literature
... uncommon in pulmonary pleomorphic adeno- ma. Pulmonary blastomas and carcinosarco- Figure 2. The histological features of the primary pleomorphic adenoma of the lung. A. The myoepithelial cells and glandular ...
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Interleukin 10 Down Regulates Cathepsin B Expression in Fetal Rat Alveolar Type II Cells Exposed to Hyperoxia
... fetal type II cells after preincubation of cathepsin B-inhibitor or ...E19 type II cells exposed to 65%- and 85%-hyperoxia for the indi- cated periods of ...time. Cells in ...
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