amphiphilic copolymer
Self-assembled micelles of novel amphiphilic copolymer cholesterol-coupled F68 containing cabazitaxel as a drug delivery system
... promising amphiphilic block copolymers, use of Pluronic F68 in drug delivery is limited due to its high critical micelle concentration ...F68-CHMC copolymer may be a potential nanocarrier to improve the ...
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Separating extreme pH gradients using Amphiphilic Copolymer Membranes
... block copolymer was synthesized via anionic polymerization using standard high vacuum techniques 18 and characterized via NMR and ...block copolymer were found to be f m ...
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<p>Co-Delivery of Curcumin and Paclitaxel by “Core-Shell” Targeting Amphiphilic Copolymer to Reverse Resistance in the Treatment of Ovarian Cancer</p>
... The amphiphilic graft copolymer (PEI-SA) consists of SA as a hydrophobic segment, PEI as a hydrophilic group and then HA was further coated as an “ antibody-receptor ” targeting group ...
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In vitro and in vivo evaluation of folate receptor-targeting amphiphilic copolymer-modified liposomes loaded with docetaxel
... A novel polymer, ie, (FA-PEG-PCHL), with a low molecu- lar weight and polydispersity index was successfully syn- thesized and used to modify docetaxel-loaded liposomes. FA-P[r] ...
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Synergistic effects of A-B-C-type amphiphilic copolymer on reversal of drug resistance in MCF-7/ADR breast carcinoma
... block copolymer PELA54 cooled and solidified, it was redissolved in anhy- drous dichloromethane and precipitated in cold diethyl ether twice to obtain a yield ...
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Effects of X-shaped reduction-sensitive amphiphilic block copolymer on drug delivery
... X-shaped amphiphilic block copolymers on delivery of docetaxel (DTX) and the reduction-sensitive property on drug release, a novel reduction-sensitive amphiphilic copolymer, (PLGA) 2 -SS-4-arm-PEG ...
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Co-delivery of cisplatin and paclitaxel by folic acid conjugated amphiphilic PEG-PLGA copolymer nanoparticles for the treatment of non-small lung cancer
... CDDP co-delivery NPs can be explained by the following reasons: (1) the inherent long circulation and EPR effect of stealth NPs would passively/actively accumulate the NPs at the tumor site; (2) the drugs cross-linking ...
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Self-assembled micelles based on pH-sensitive PAE-<em>g</em>-MPEG-cholesterol block copolymer for anticancer drug delivery
... novel amphiphilic triblock pH-sensitive poly(β-amino ester)-g-poly(ethylene glycol) methyl ether-cholesterol (PAE-g-MPEG-Chol) was designed and synthesized via the Michael-type step polymerization and ...
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Immune activity and biodistribution of polypeptide K237 and folic acid conjugated amphiphilic PEG-PLGA copolymer nanoparticles radiolabeled with 99m Tc
... study, amphiphilic copolymer, polypeptide K237 (HTMYYHHYQHHL) and folic acid (FA) modified poly(ethylene glycol)-poly(lactic-co-glycolic acid) (K237/ FA-PEG-PLGA) nanoparticles were developed and studied as ...
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Amphiphilic graft copolymer based on poly(styrene-co-maleic anhydride) with low molecular weight polyethylenimine for efficient gene delivery
... new amphiphilic comb-shaped copolymer (SP) by conjugating SMA with low molecular weight PEI (PEI 800) for gene ...new amphiphilic copolymer would show high transfection efficiency with low ...
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pH-Responsive Vesicles with Tunable Membrane Permeabilityand Hydrodynamic Diameters from Self-Catalyzed Cross-Linkable Amphiphilic Block Copolymer
... block copolymer and characterized the stability of the block copolymer during ...block copolymer preparation and drug loading, and provided possible cross-linking without addition of cross-linker of ...
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Novel lactoferrin-conjugated amphiphilic poly(aminoethyl ethylene phosphate)/poly(L-lactide) copolymer nanobubbles for tumor-targeting ultrasonic imaging
... The PAEEP-PLLA copolymer used as the shell material for the NBs had good mechanical properties, which stretched under ultrasound irradiation. The NBs were turned into larger NBs or microbubbles when the PFP core ...
13
Amphiphilic poly{[α-maleic anhydride-ω-methoxypoly(ethylene glycol)]-co-(ethyl cyanoacrylate)} graft copolymer nanoparticles as carriers for transdermal drug delivery
... Skin samples were obtained from adult Kunming rat (Tianjin Institute of Pharmaceutical Research, Tianjin, China). The subcutaneous fat tissue was removed before experiments. In vitro release was carried out at 37 ° C ...
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The encapsulation of an amphiphile into polystyrene microspheres of narrow size distribution
... an amphiphilic molecule with limited solubility in both water and most common organic solvents, as well as an amphiphilic antibiotic, tetracycline, may be solvated and trapped in the organic phase of a ...
6
Amphiphilic Block Copolymer for adsorption of Organic Contaminants
... Novel polymeric adsorbents, 2 types of polystyrene- block-poly (N-isopropylacrylamide) (PSN), were de- veloped and could be applied for removal of dissolved organic pollutants from wastewater. When this novel material is ...
6
Sensors Based on Molecularly Imprinted Polymers
... MIPs derived from acrylamide are another available platform. The polymerized form, polyacrylamide, has broad application and polyacrylamide gel electrophoresis is based just on this compound. The polymerization principle ...
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Novel Acrylic copolymers based on Schiff base: Synthesis, characterization and antimicrobial activity
... All the homo and copolymers of MSB and MMA were screened for antimicrobial activity against various microbial. The results related to antimicrobial activity are presented in Figure 4, 5 and 6 respectively for bacteria, ...
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Journal of Polymer and Biopolymer Physics Chemistry
... PVP-PVOH copolymer in ...PVOH copolymer, meaning that the end groups at the end of the polymer are less meaningful in determining chemical ...PVP-PVOH copolymer has the PVP and PVOH moieties located ...
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Optimization of energy transfer in a polymer composite with perylene chromophores
... To show our goal visually, we calculated the idealized excitation-emission spectrum of the sensitizer-emitter copolymer. This is achieved by computing the matrix which is the outer prod- uct of two vectors: the ...
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The synthesis and conjugation chemistry of polymeric precursors for medicine
... block copolymer, poly(MOSu-b-ethylene glycol) 56, could successfully be prepared by using a PEG macro-initiator 55 synthesised by the functionalisation of monomethoxy-PEG ...
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