Amphotericin B
<p>Lipsosomal amphotericin B: a review of its properties, function, and use for treatment of cutaneous leishmaniasis</p>
... 1960s, amphotericin B deoxycholate was introduced as a second-line therapy for CL and ...regions. Amphotericin B binds to ergosterol in the photogenic cell membranes and causes changes in ...
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Cationic nanoparticles for delivery of amphotericin B: preparation, characterization and activity in vitro
... deliver drugs with higher efficiency with fewer adverse side effects [6,8]. A possible mechanism is increase of cel- lular drug uptake by endocytosis of the drug carriers [9- 11]. The emergence of the newer forms of SLN ...
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Filamentous fungal endophthalmitis: results of combination therapy with intravitreal amphotericin B and voriconazole
... This was a retrospective study of 12 consecutive endophthal- mitis cases caused by filamentous fungi that were managed at our center between January 2013 and August 2013. All patients treated with a combination of ...
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Antimycotic-Antibiotic Amphotericin B Promotes Influenza Virus Replication in Cell Culture
... antibiotic amphotericin B (AmB) on influenza virus growth in Vero ...and B viruses from clinical samples can be dramatically enhanced by adding AmB to the culture ...
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Sterol 14α demethylase mutation leads to amphotericin B resistance in Leishmania mexicana
... polyene amphotericin B (AmB) has emerged as the treatment of choice where avail- able, particularly in the liposomal formulation which abrogates some of the toxic effects associ- ated with the parent ...
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Formulation of Amphotericin B lipid derivatives and feasibility for nebulization and their stability study
... Sodium deoxycholate (SDCS, 245 mg) was taken in beaker (100 mL) containing 30 mL distilled water and added sodium hydroxide (2.7 mL, 0.2M) to this solution with constant stirring (500 rpm) in a magnetic stirrer Heidolph ...
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Direct vasoconstriction as a possible cause for amphotericin B induced nephrotoxicity in rats
... In anesthetized rats we tested the hypothesis that amphotericin B (AmB) reduces glomerular filtration rate (GFR) by activating the tubuloglomerular feedback (TGF) mechanism. Infusion of 1 mg/kg AmB over 50 ...
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Efficacy of Oral Encochleated Amphotericin B in a Mouse Model of Cryptococcal Meningoencephalitis
... of amphotericin B. While absolute levels of amphotericin B can vary tremendously in plasma and tissue between preparations that have similar efficacies and thus may have limited predictive ...
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Short-Course Amphotericin B Therapy for Candidemia in Pediatric Patients
... short-course (7 to 14 days of therapy after the last positive blood culture) amphotericin B therapy for candidemia in children.. Design.[r] ...
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IN VITRO SENSITIVITY OF AMPHOTERICIN B, ITRACONAZOLE AND FLUCONAZOLE – RESISTANT AGAINST CANDIDA ALBICANS
... confer resistance to ‘novel’ synthetic drugs have been selected from an extensive repertoire that has enabled microorganisms to survive for so long in changing environments 9, 10 . The efficacy of commonly used ...
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FORMULATION AND CHARACTERIZATION OF AMPHOTERICIN B LIPOSOMES PREPARED BY THIN FILM HYDRATION METHOD
... Amphotericin B is a polyene antifungal drug, often used intravenously for systemic fungal ...amphotericins, amphotericin A and amphotericin B are known, but only B is used ...
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Novel Method for Evaluating In Vitro Activity of Anidulafungin in Combination with Amphotericin B or Azoles
... cells treated with drug combinations divided by the fluorescence of the drug alone for FUN-1. Hence, SI ⫽ (DC AND ⫹ AMB/DC AND) ⫹ (DC AND ⫹ AMB/DC AMB) for AND-AMB association and SI ⫽ (MIF AND ⫹ azole/MIF AND) ⫹ (MIF ...
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Efficacy of intravenous amphotericin B-polybutylcyanoacrylate nanoparticles against cryptococcal meningitis in mice
... Abstract: Amphotericin B deoxycholate (AmB), a classic antifungal drug, remains the initial treatment of choice for deep fungal infections, but it is not appropriate for treatment of cryptococcal meningitis ...
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Amphotericin B deoxycholate for relapse visceral leishmaniasis in Bangladesh: a cross sectional study
... liposomal amphotericin B is 86% effective, however, they included only those who treated before low-dose non- liposomal amphotericin B and they used 20–25 infusions based on parasitological ...
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Enhanced antifungal effects of amphotericin B-TPGS-b-(PCL-ran-PGA) nanoparticles in vitro and in vivo
... Background: Amphotericin B (AMB) is a polyene antibiotic with broad spectrum antifungal activity, but its clinical toxicities and poor solubility limit the wide application of AMB in clinical ...
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Topical Amphotericin B formulas: Promising new application
... Amphotericin B (AmB) is the more effective drugs used against different types of systemic fungal infections. Although it used over more than 50 years, it's still the first choice for treating serious fungal ...
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Application of caspofungin in China compared with amphotericin B and fluconazole
... and amphotericin B are resistant to fungal infection or have more adverse events, while caspofungin showed equivalent efficacy in treating fungal infection in Chinese clinical ...
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THE EFFECT OF FLUCONAZOLE AND AMPHOTERICIN B ON MACROPHAGE FUNCTIONS
... Materials and Methods: In the present study we investigated the effect of amphotericin B and flucona- zole on the functions of peritoneal macrophages from Balb/c mice treated with these antimycotics. For ...
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Proven invasive pulmonary mucormycosis successfully treated with amphotericin B and surgery in patient with acute myeloblastic leukemia: a case report
... Histologic examination of the new specimen was done, as well as a revision of the earlier samples in the refer- ence laboratory and the diagnosis was switched to pul- monary IMM (Figure 1C). Voriconazole therapy had been ...
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Trichosporon beigelii, an emerging pathogen resistant to amphotericin B
... beigelii may be resistant in vitro to amphotericin B and that this in vitro resistance was correlated with refractory, disseminated trichosporonosis in granulocytopenic patients.. beigel[r] ...
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