Amyloid deposition
Case Report Pulmonary arterial hypertension due to pulmonary vascular amyloid deposition in a patient with multiple myeloma
... the deposition of amorphous eosinophilic mate- rial was found in systemic blood vessels, mainly in the vascular media of elastic arteries and relatively thick muscular arteries (outer media > 100 ...The ...
5
Typing of hereditary renal amyloidosis presenting with isolated glomerular amyloid deposition
... glomerular amyloid deposits without tubulointerstitial and vascular amyloid deposition, which suggested the type of AFib as ...of amyloid as ApoA-I in case 1, and fibrinogen Aα chain in case ...
8
Prevalence of amyloid deposition in long standing rheumatoid arthritis in Iranian patients by abdominal subcutaneous fat biopsy and assessment of clinical and laboratory characteristics
... of amyloid deposition in Iranian patients using fat-pad biopsy method; it also sought to establish whether and how its occurrence correlated with the clinical and laboratory findings and data ...
6
β-amyloid deposition is shifted to the vasculature and memory impairment is exacerbated when hyperhomocysteinemia is induced in APP/PS1 transgenic mice
... of amyloid deposition as CAA or paren- chymal plaques is relatively ...of amyloid at the vasculature while preserving the parenchymal amyloid-lowering prop- erties of the antibody ...
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In vivo staging of regional amyloid deposition
... model, amyloid deposition begins in temporobasal and frontome- dial areas, and successively affects the remaining associative neocortex, primary sensory-motor areas and the medial temporal lobe, and finally ...
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Genetic epistasis regulates amyloid deposition in resilient aging
... the amyloid cascade and contribute to the accumulation of pathogenic Aβ species [3], consistent with our observations of concomitant increases in diffuse plaques postmortem and amyloid burden in ...
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Monoclonal Gammopathy of Undetermined Significance with Amyloid Deposition in the Lung and Non-Amyloid Eosinophilic Deposition in the Brain: A Case Report
... Background. Monoclonal gammopathy of undetermined significance (MGUS) is rarely complicated by amyloidosis. Case. A 66-year-old white male presented to the emergency room (ER) after an unwitnessed fall and change in ...
5
Dietary patterns and β amyloid deposition in aging Australian women
... b deposition in healthy aging Australian ...b deposition [10] and hypothesized this was due to limitations of the self-reported food frequency questionnaire in measuring the potentially beneficial ...
7
Hippocampal expression of murine IL-4 results in exacerbation of amyloid deposition
... plaque deposition has started) and were analyzed after 6 weeks (n = 6 for rAAV1- mIL-4; n = 6 for ...on amyloid pathology or gliosis when compared to naïve uninjected mice [10,18,19]; so, AAV1-EGFP injected ...
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Hippocampal expression of murine TNFα results in attenuation of amyloid deposition in vivo
... Amyloid b (Ab) plaques are a hallmark pathological fea- ture of Alzheimer’s disease (AD). Neuroinflammation, characterized by Ab plaque associated reactive gliosis and increased levels of pro-inflammatory ...
10
Vitreous amyloidosis with autonomic neuropathy of the digestive tract associated with a novel transthyretin p Gly87Arg variant in a Bangladeshi patient: a case report
... normal in both eyes (15 mmHg). No pars plana vitrectomy was performed. A slit-lamp biomicroscopy showed abnor- mal conjunctival vessels with keratoconjunctivitis sicca. No change of the pupillary shape and no ...
5
Diffuse Lipomatosis of Thyroid—Case Report
... with amyloid deposition [7], the mechanisms underlying fatty tissue development in thyroid lesions have not been clearly described [8], but the pos- sibility of congenital goiter with fatty change cannot be ...
5
A Case Report of the Association Renal AA Amyloidosis and Thyroid Papillary Carcinoma
... AA amyloidosis is often secondary to chronic inflammatory diseases but can rarely occur in patients with malignant neoplasms. A 33 years old woman with papillary carcinoma of thyroid was hospitalized in our department of ...
5
The lung in amyloidosis
... parenchymal amyloid is common in systemic AL ...widespread amyloid deposition involving the small vessels and the interstitium, with reticular opacities, interlobular septal thickening, micronodules ...
8
Significant association between renal function and amyloid-positive area in renal biopsy specimens in AL amyloidosis
... [4]. Amyloid deposition into peripheral and autonomic nerves reveals sensory disturbance and orthostatichypotension ...by amyloid deposition into tendons in the wrist joint and is a sensitive ...
7
18F-fluorodeoxyglucose positron emission tomography might be useful for diagnosis of hepatic amyloidosis
... We report a case of hepatic involvement of primary systemic (immunoglobulin light chain, AL) amyloidosis, with severe amyloid deposition in the liver. Of note in this patient, fluorodeoxyglucose (FDG) ...
7
Cerebral amyloid angiopathy presenting as a brain mass
... Systemic amyloid deposition, known as amyloidosis, is found in patients with gammopathies or plasma cell ...Localized amyloid deposition occurring within the media and intima of the arteries ...
5
Stepping closer to treating Alzheimer’s disease patients with BACE1 inhibitor drugs
... of amyloid precursor protein (APP) at the β -secretase ...targeting amyloid deposition-mediated pathology for AD therapy has now become more ...and deposition with no alarming safety concerns, ...
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Mini review: linkage between α Synuclein protein and cognition
... detected in 52% of the general population and its level of expression did not change between ages 40 and 91, while all PD patients with α-synuclein positive and expressed higher α-synuclein levels than that in the ...
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Can brain impermeable BACE1 inhibitors serve as anti-CAA medicine?
... The experimental data suggesting a key role of BACE1 upregulation in the pathogenesis of CAA by mediating Aß overproduction in local cellular components, as as- sembled in our dual-origin hypothesis (Fig. 2k), highlight ...
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