and hyperinsulinemia
Original Article Clinical efficacy of metformin combined with lifestyle intervention for treatment of childhood obesity with hyperinsulinemia
... and hyperinsulinemia has gradually re- ceived attention ...in hyperinsulinemia patients ...treating hyperinsulinemia by com- bining with lifestyle improvements of obese ...and hyperinsulinemia ...
7
Errata: Hyperinsulinemia: A unifying theory of chronic disease?
... that hyperinsulinemia is independent to insulin resistance: Hyperinsulinemia is excessive insulin secretion, while insulin resistance is impaired glucose ...links hyperinsulinemia to metabolic ...
11
Levels of TNF α, IL 1β, TGF β, and IL 6 in patients with chronic hepatitis C virus infection and hyperinsulinemia
... with hyperinsulinemia, and in 40 normoinsulinemic chronic HCV-infected patients with at least 10 years of ...patients. Hyperinsulinemia patients had a higher HOMA- IR value ...with hyperinsulinemia ...
7
SGLT2 inhibition slows tumor growth in mice by reversing hyperinsulinemia
... result, hyperinsulinemia by correcting non-alcoholic fatty liver disease (NAFLD) [34], and that the reversal of hyperinsulinemia slows tumor growth in two mouse models of colon cancer, MC38 tumor-bearing ...
13
Basal hyperinsulinemia beyond a threshold predicts major adverse cardiac events at 1 year after coronary angiogram in type 2 diabetes mellitus: a retrospective cohort study
... Since hyperinsulinemia/insulin resistance is known to be associated with the cardiac events, we hypothesize that, in addition to severity of the disease, there might be a threshold value for basal insulin/insulin ...
8
Influence of Continuous Physiologic Hyperinsulinemia on Glucose Kinetics and Counterregulatory Hormones in Normal and Diabetic Humans
... It is concluded that a in normal and diabetic subjects, physiologic hyperinsulinemia results in an initial decline followed by stabilization of plasma glucose despite ongoing infusion of[r] ...
10
Effect of physiologic hyperinsulinemia on skeletal muscle protein synthesis and breakdown in man
... forearm hyperinsulinemia (124 +/- 11 microU/ml), the net balance of phenylalanine and leucine became positive (9 +/- 3 and 61 +/- 8 nmol/min per dl, respectively (P less than ...
7
Effects of prolonged hyperinsulinemia on serum leptin in normal human subjects
... prolonged hyperinsulinemia and hyperglycemia on serum leptin levels in young non- obese males during 72-h euglycemic–hyperinsulinemic and hyperglycemic ( z ...
8
Task-related fMRI BOLD response to hyperinsulinemia in healthy older adults
... Behaviorally, we observed improved RTs on 2-back trials associated with the degree of task-related BOLD increase between insulin and saline conditions within several clusters, including the RH thalamus, posterior ...
15
Effects of acute systemic hyperinsulinemia on forearm muscle proteolysis in healthy man
... To investigate the mechanism(s) of insulin-induced suppression of plasma amino acid concentration and release, we studied forearm as well as whole-body leucine and phenylalanine uptake and release during a peripheral ...
8
Regulation of glucose utilization in adipose cells and muscle after long term experimental hyperinsulinemia in rats
... of hyperinsulinemia on insulin binding and glucose metabolism persisted and were superimposed on the changes in cell function that occurred with increasing cell size in aging ...rats. Hyperinsulinemia for 2 ...
11
Effect of physiologic hyperinsulinemia on glucose and lipid metabolism in cirrhosis
... mumol/kg.min, P less than 0.01) were elevated in cirrhotics despite basal hyperinsulinemia; basal FFA oxidation was similar in cirrhotic and control subjects. With low-dose insulin infusion, plasma FFA oxidation ...
11
The Diagnosis of Insulinoma in a Child in the Absence of Fasting Hyperinsulinemia
... The Diagnosis of Insulinoma in a Child in the Absence of Fasting Hyperinsulinemia. http://pediatrics.aappublications.org/content/64/4/496[r] ...
5
HYPOGLYCEMIA AND HYPERINSULINEMIA ASSOCIATED WITH ERYTHROBLASTOSIS FETALIS
... Correlation of umbilical vein plasma insulin and free fatty acid levels. ( FFA) in 39 infants with erythroblastosis fetalis[r] ...
11
GLP-1 RECEPTOR ACTIVATION-BASED THERAPY; A PROMISING STRATEGY AGAINST ISCHEMIC STROKE
... and hyperinsulinemia decrease the activity of recombinant tissue plasminogen activator (rtpa) treatment in animal models of ischemic stroke (28, 29), The correlation between hyperglycemia and aggravated cerebral ...
6
Effect of leptin infusion on insulin sensitivity and lipid metabolism in diet-induced lipodystrophy model mice
... and hyperinsulinemia through the drastic reduction of adipocytokine levels due to a paucity of adipose tissue in mice and the pathogenesis of these metabolic abnormalities in CLA-fed mice is similar to that in ...
8
Metabolic Syndrome: From the Pathophysiology to the Treatment. A Comprehensive Review
... Insulin is made in the pancreas by β-cells in response to hyperglycemia and stimulates glucose use differently in various tissues. The tissues that remove glucose from the circulation are skeletal muscle, liver and ...
8
Hyperinsulinemia: A unifying theory of chronic disease?
... Diagnosing hyperinsulinemia is challenging partly because the health effects of insulin resistance and hyperinsulinemia have been ...diagnosing hyperinsulinemia with differing ...
10
Hormonal control of substrate cycling in humans
... The stimulatory effect of high dose glucagon on TG/FA cycling was almost certainly due to the resultant hyperglycemia and hyperinsulinemia stimulating reesterification, since Ra glycerol[r] ...
12
Characterization of cellular defects of insulin action in type 2 (non insulin dependent) diabetes mellitus
... In conclusion, in NIDDM: a insulin resistance involves glycolysis, glycogen synthesis, and glucose oxidation; b hyperglycemia and hyperinsulinemia can normalize total body glucose uptake[r] ...
12