and squalene.
Squalene synthase cloning and functional identification in wintersweet plant (Chimonanthus zhejiangensis)
... Cloning of squalene synthase genes from wintersweet The transcriptome of the C. zhejiangensis foliage was sequenced by Illumina. The data was assembled by the Trinity software (Grabherr et al. 2011) and the result ...
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Improving squalene production by enhancing the NADPH/NADP+ ratio, modifying the isoprenoid-feeding module and blocking the menaquinone pathway in Escherichia coli
... To improve the FPP pool for squalene synthesis, flux to the isoprenoid pathway should be enhanced. The iso- prenoid pathway, fed by the Embden–Meyerhof path- way (EMP), starts with the condensation of pyruvate and ...
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Occurrence of squalene and cholesterol in various species of Czech freshwater fish
... high squalene diet is identified as an unquestionable cause of the increased LDL cholesterol level in blood plasma of humans (Pedersen et ...high squalene diet does not raise the levels of triacyl- ...
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Molecular Characterization of a Squalene Synthase Gene from Phellinus igniarius
... According to the conserved sequence of SQS （ squalene synthase ） from NCBI database, designed primers and amplified SQS gene fragment with RT-PCR product from Phellinus igniarius total RNA. Then obtained full ...
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Squalene-Adenosine Nanoparticles: Ligands of Adenosine Receptors or Adenosine Prodrug?
... to squalene to form squalene-adenosine (SQAd) nanoparticles (NPs) dramatically improved the pharma- cological efficacy of adenosine, especially for neuroprotection in stroke and spinal cord ...
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Fatty acid, tocopherol and squalene contents of Rosaceae seed oils
... Squalene, a 30 carbon isoprenoid, is a key intermediate in cholesterol biosynthesis and is abundant in shark liver oil and olive oil (Ryan et al. 2007). More recently, squa- lene has been shown to act as an ...
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EVALUATION OF ANTICANCER ACTIVITY OF SQUALENE ISOLATED FROM CANTHIUM COROMANDELICUM LEAVES
... of squalene isolated from the leaves of Canthium coromandelicum. Squalene structure was elucidated using spectroscopic ...of squalene from Canthium ...
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Synthesis of Novel Hexathiolated Squalene and Its Thiol Ene Photopolymerization with Unsaturated Monomers
... Squalene (SQ), thiol acetic acid (TAA), sodium hydrox- ide, 2,2-Dimethoxy-2-phenylacetophenone (DMPA), die- thylenglycol divinyl ether (DEGVE), triallyl cyanurate (TAC), pentaerythritol triacrylate (PETA), were ...
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5 Aminolevulinic Acid Squalene Nanoassemblies for Tumor Photodetection and Therapy: In Vitro Studies
... Protoporphyrin IX (PpIX) as natural photosensitizer derived from administration of 5-aminolevulinic acid (5-ALA) has found clinical use for photodiagnosis and photodynamic therapy of several cancers. However, broader use ...
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Co-production of ethanol and squalene using a Saccharomyces cerevisiae ERG1 (squalene epoxidase) mutant and agro-industrial feedstock
... of squalene epoxidase expres- sion. Enhanced accumulation of squalene at the expense of other sterol intermediates has previously been re- ported in ...the squalene epoxi- dase inhibitor, terbinafine ...
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Squalene Extraction: Biological Sources and Extraction Methods
... decade, squalene is extracted from different sources and methods to achieve best yields at lower possible ...obtain squalene from biological matrix is supercritical fluid extraction with CO 2 as solvent ...
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BIOINFORMATICS ANALYSIS ON SQUALENE EPOXIDASE 2 IN PANAX NOTOGINSENG
... in squalene epoxidase 2 are systematically studied, the basic physical and chemical properties of squalene epoxidase 2 are predicted, which provided a reference for understanding the value of Panax ...the ...
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THE EFFECTS OF SQUALENE ON THE INCORPORATION OF ACETATE INTO PLASMA CHOLESTEROL IN MAN
... Quantity of free cholesterol derived from squalene In comparison to dogs, if it is assumed that the delay in appearance of the peak specific activity in the plasma free cholesterol in ma[r] ...
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CHOLESTEROL BIOSYNTHESIS STUDIES RELATED TO THE METABOLIC ROLE OF SQUALENE
... Oral administration of hydrocarbon fraction containing squalene-T in the human The specific activity of plasma-free cholesterol following oral administration of the hydrocarbon fraction [r] ...
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DESIGNING OF COUMARIN DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS
... The main intention of this research work is to design a library of novel coumarin derivatives by docking evaluation of the designed coumarin derivatives as squalene synthase inhibitor. Coumarins are the compounds ...
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The Biosynthesis of Squalene from Acetate in Man
... If this is assumed to be the case for the human, then the skin cholesterol specific activity may reach a maximum value within several hours after the administration of the labeled acetat[r] ...
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Squalene in Human and Rat Blood Plasma
... Approximately half the free sterol fractions from the three lipoproteins corresponding to rat plasma sample A, and from those of the third 4.8-hour human plasma sample, were each combine[r] ...
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Engineering the oleaginous yeast Yarrowia lipolytica for production of α-farnesene
... with rate-limiting enzyme IDI, which converts IPP to dimethylallyl diphosphate and plays an important role in the distribution of geranyl diphosphate (GPP) and FPP flux, and mevalonate kinase, whose overexpression pro- ...
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Lipid Profile and Antioxidant Activity of Macadamia Nuts (Macadamia integrifolia) Cultivated in Venezuela
... characteristics, but also the presence of tocopherols and tocotrienols (Vitamin E), its antioxidant capacity, and revealing the presence of squalene. Moreover, the significance and novelty of this study lies, as ...
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IDENTIFICATION OF BIOACTIVE COMPOUNDS IN LOESENERIELLA ARNOTTIANA WIGHT ROOT BY GC MS ANALYSIS
... Loeseneriella arnottiana is commonly used in the folklore medicine for treating diabetes mellitus. Preliminary phytochemical analysis of root extract revealed the presence of tannins, flavonoids, saponins, glycosides, ...
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