androgen receptors
Androgen receptors influence the production of pulmonary surfactant in the testicular feminization mouse fetus
... A sexual dimorphism in fetal pulmonary maturation has been described in which the female fetal lung produces surfactant earlier in gestation than the male fetal lung. This is felt to be related to the increased incidence ...
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In-silico Screening of Compounds Contained in Wera (Malvaviscus Arboreus Cav.) Leaves as Anti-alopecia with Androgen Receptors
... Objective: Baldness (Alopecia) is a serious problem at this time because it is caused by stress, genetic factors, pregnancy, inadequate hair care, and less balanced nutrition. Previous studies have shown that ethanol ...
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Defective nuclear accumulation of androgen receptors in disorders of sexual differentiation
... of androgen receptors (AR) and glucocorticoid receptors (GR) was determined in cultured genital skin fibroblasts from 10 normal controls and eight patients with abnormalities of the external ...
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Immunohistochemical Detection of Androgen Receptors in Prostate Tumors
... This study aimed to detect the expression of androgen receptors (AR) in prostate tumors. Forty formalin fixed paraffin blocks (FFPB) previously diagnosed as prostate tumors were selected for this study (27 ...
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Predictive value of GGN and CAG repeat polymorphisms of androgen receptors in testicular cancer: a meta-analysis
... with androgen insensitivity, and previous studies have proposed that GGN and CAG repeats in androgen receptors (AR) could be related to the risk of ...
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miR 141 3p Suppresses Expression of Androgen Receptors and Functions as a Tumor Suppressor Gene in Prostate Carcinogenesis
... is androgen regulated in PCa cell lines and xenografts [12], and modulates transcriptional activity of AR by targeting the small heterodimer partner protein (Shp), a corepressor to AR ...of androgen ...
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Androgen receptors beyond prostate cancer: an old marker as a new target
... in androgen (and estrogen) synthesis that, when targeted, specifically suppresses adrenal androgens ...intermittent androgen suppression which holds the promise of decreasing toxicity while maintaining ...
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Caloric restriction increases ratio of estrogen to androgen receptors expression in murine ovaries - potential therapeutic implications
... on androgen levels [8, 12, 15, 16], one can speculate that follicular develop- ment is normal in the androgen-dependent stages of folliculogenesis in mice under CR and diminished in the estrogen-dependent ...
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Cancer and Germ Cells
... ceptors:androgen receptors in breast, prostate well differentiated cancers respectively are, prob- ably a compensatory rise, secondary to the sudden artificially acquired contraception resulting in significant ...
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Amino acid substitutions in the hormone binding domain of the human androgen receptor alter the stability of the hormone receptor complex
... ligand-bound receptors to activate a reporter gene were ...mutant androgen receptors to incubation with testosterone, 5 alpha-dihydrotestosterone, and ...
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Sertoli-Leydig cell tumor with unique nail findings in a post-menopausal woman: a case report and literature review
... serum androgen levels postoperatively in this ...via androgen receptors (AR), we presumed that there are androgen receptors located within nail bed ...bed androgen expression ...
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Cytochrome P450arom, androgen and estrogen receptors in pig sperm
... The androgen and estrogen targeting of porcine male gen- ital tract has been a subject of interest in different recent ...investigations. Androgen receptors have been detected in somatic cells of pig ...
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Contributions of androgen and estrogen to fetal programming of ovarian dysfunction
... function. Androgen deficiency, without accompanying estrogen deficit, has little apparent impact on ovarian ...Fetal androgen excess, on the other hand, mediated either by direct androgen action or ...
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LSD1 inhibition attenuates androgen receptor V7 splice variant activation in castration resistant prostate cancer models
... S4. Androgen response element (ARE) luciferase reporter assay, in response to androgen receptor (AR) antagonists, for the AR wild type (WT) or V7 splice variant ...
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Supraphysiologic Testosterone Therapy in the Treatment of Prostate Cancer: Models, Mechanisms and Questions
... the androgen-sensitive nature of prostate cancer (PCa), suppression of systemic testosterone (T) has remained the most effective initial therapy for advanced disease although progression inevitably ...suppress ...
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Recent advances on the progressive mechanism and therapy in castration-resistant prostate cancer
... tumoral androgen is related to the tumor microenvironment to a certain ...through androgen receptor (AR) activation in CRPC cells, could also be enhanced by prostate stromal ...
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The Role of Neurotransmitters in Anesthesia
... It is one of the major inhibitory neurotransmitters in posterior areas of the central nervous system, spinal cord, brainstem, and retina. In the spinal cord and brain stem, glycinergic interneurones provide an inhibitory ...
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DAX 1 expression in human breast cancer: comparison with estrogen receptors ER α, ER β and androgen receptor status
... estrogen receptors (ERs): ER- α and ER- β ...two receptors suggest that the genes encoding ER- α and ER-β are differentially expressed in various ...Both receptors have distinct cellular ...
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Androgen therapy
... cancer. In addition, the total number of men taking androgen therapy was not reported. Among those who did get prostate cancer, PSA testing was carried out before androgen therapy commenced for 100% of ...
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Interactions between cancer cells and bone microenvironment promote bone metastasis in prostate cancer
... with androgen dep- rivation therapy (ADT), including chemical or surgical castration, which decreases the tumor size and serum prostate-specific antigen (PSA) level ...[21]. Androgen receptor vari- ants ...
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