Ang-1
Local intra-uterine Ang-(1–7) infusion attenuates PGE2 and 6-keto PGF1α in decidualized uterus of pseudopregnant rats
... the 1 st trimester of aborted pregnancy ...of Ang-(1-7) and whether local changes of Ang-(1-7) and prostanoids in the im- plantation site are important in influencing the suc- cess of ...
6
Original Article Optimizing dosage regimen for FP3 based on vascular normalization window monitored by ratio of Ang-1 to Ang-2
... Serum Ang-1 and Ang-2 expression were detected by ...and Ang-1/Ang-2 ratio were ...of Ang-1/Ang-2 was demonstrated as an effective surrogate maker for ...
10
Evaluation of mRNA/ Gene Expression of Pro-Angiogenic Factors – Ang 1, Ang 2 and HGF in Periodontal Health and Disease
... of Ang 1, Ang 2 and HGF in periodontal disease based on previous reports that the proangiogenic factors play a role in vascular turnover and remodeling in chronic ...
124
Angiotensin-Converting Enzyme (ACE) 2 Overexpression Ameliorates Glomerular Injury in a Rat Model of Diabetic Nephropathy: A Comparison with ACE Inhibition
... therapy (10) and confers renoprotection in experimental and human diabetic kid- ney disease (11). However, the antipro- teinuric efficacy of these RAS inhibitors depends at least in part on ACE2 (12) and its major ...
11
Deterioration of alveolar development in mice with both HIF 3α knockout and HIF 2α knockdown
... conditions. Ang-1 that is interestingly highly expressed even though HIF-1α is inversely expressed in the lung of the neonatal double-mutant mice, which against the pre- vious report concluding HIF-1α ...
6
Imbalances in serum angiopoietin concentrations are early predictors of septic shock development in patients with post chemotherapy febrile neutropenia
... biomarker behaves differently in diseased and normal individuals (phase I) to the ultimate demonstration of improved clinical outcomes after its incorporation (phase IV) [31]. Ours is a phase II study in which the ...
10
Panaxatriol saponins promotes angiogenesis and enhances cerebral perfusion after ischemic stroke in rats
... VEGF, Ang-1, HIF-1, bFGF, and EPO. VEGF and Ang-1 play the most prominent roles in angiogenesis after is- chemic ...edema. Ang-1 promotes angiogenesis and new vessel ...
10
Serum angiopoietin is associated with lung function in patients with asthma: a retrospective cohort study
... whereas Ang-1 protects against microvascular leakage induced by VEGF, Ang-2, or inflam- matory agents ...[13-16]. Ang-2 is released from endothelial cells [17] and human monocytes [18], while ...
7
Endothelial activation, haemostasis and thrombosis biomarkers in Ugandan children with severe malaria participating in a clinical trial
... regulators Ang-1 and Ang-2, as well as other markers of endothelial activation ...studies, Ang-2 was an independent and quantitative marker of malaria-related morbidity and mortality and a ...
9
Topological analysis of the vasculature of angiopoietin-expressing tumours through scale-space tracing
... of Ang-2 was associated with susceptibility of the tumour vasculature to the vascular disrupting agent, combretas- tatin A4 phosphate ...tumour Ang-2 expression as a predictive bio-marker for response to ...
13
Circulating angiopoietin 1 and angiopoietin 2 in critically ill patients: development and clinical application of two new immunoassays
... anti-human Ang-1 affinity-purified goat IgG anti- body (PAB) and a monoclonal anti-human Ang-1 mouse anti- body were obtained from R&D Systems (Minneapolis, MN, ...human ...
11
Different patterns of inflammatory and angiogenic factors are associated with peritoneal small solute transport and peritoneal protein clearance in peritoneal dialysis patients
... Assessment of markers of inflammation and angiogenesis The concentrations of inflammatory and angiogenic makers in the serum and overnight effluent were deter- mined using the ELISA technique. All samples were run ...
9
Circulating levels of soluble Fas (sCD95) are associated with risk for development of a nonresolving acute kidney injury subphenotype
... We have shown that a biomarker of Fas pathway activity, sFas, is associated with the risk of developing a nonre- solving AKI subphenotype in critically ill patients with- out major trauma, severe immune suppression, or ...
9
Expression of Ets-1, Ang-2 and maspin in ovarian cancer and their role in tumor angiogenesis
... including Ang-1, Ang-2, Ang-3 and Ang-4, and the receptors of Angs are called ...angiogenesis: Ang-1 and Ang-4 are agonist ligands for Tie2 and induce tyrosin ...
6
PubMedCentral-PMC5646358.pdf
... renal Ang II levels could increase the risk for renal inflammation and fibrosis and may lead to HTN and renal disease ...of Ang-(1–7) were higher among ANCS- exposed adolescents, which might serve to ...
13
The Antithrombotic Effect of Angiotensin-(1-7) Involves Mas-Mediated NO Release from Platelets
... vehicle, Ang-(1-7) (1, 10, 100, or 1000 pmol/kg/min), A-779 (1000 pmol/ kg/min) or Ang-(1-7) (10 pmol/kg/min), combined with A-779 (1000 pmol/kg/min) through the jugular vein, starting ...
8
A high angiopoietin 2/angiopoietin 1 ratio is associated with a high risk of septic shock in patients with febrile neutropenia
... the Ang-2/Ang-1 ratio as a continuous variable on the risk of septic shock development and sepsis- related mortality, a Cox proportional-hazards model was used assuming a graded relation between the ...
10
Prognostic significance of the angiopoietin 2/angiopoietin 1 and angiopoietin 1/Tie 2 ratios for early sepsis in an emergency department
... reported Ang-2/Ang-1 ratios in patients with sepsis, and the evi- dence of similar Ang-1/Tie-2 ratios has been ...of Ang-2/Ang-1 ratio at baseline were not robust ...
11
A prospective study of endothelial activation biomarkers, including plasma angiopoietin 1 and angiopoietin 2, in Kenyan women initiating antiretroviral therapy
... Canada; 1:1000 dilution, 45-minute incubation) followed by addition of p-nitrophenyl phos- phate substrate (Sigma-Aldrich Canada Ltd, Oakville, ON, Canada) before optical density reading at 405 ...follows: ...
11
Original Article Calpeptin prevents angiopoietin-1-induced proliferation of non-small cell lung cancer A549 cells
... [20]. Ang-1 is one of the important regulators of blood vessel devel- ...opment. Ang-1 and Ang-2 are counteracting ligands for the endothelial receptor, tyrosine kinase Tie-2, and are ...
6