Angiogenesis and migration
HCRP-1 regulates cell migration, invasion and angiogenesis via Src/ FAK signaling in human prostate cancer
... cell migration, invasion and angiogenesis, PC3 and LnCap cells were transfected with siRNA for HCRP-1, phosphorylation of Src and FAK was ...the migration signaling pathway [16, ...adhesion, ...
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<p>miR-503 Inhibits Proliferation, Migration, And Angiogenesis Of Glioma By Acting On VEGFA Through Targeting LRIG2</p>
... tumor angiogenesis, the expression levels of LRIG2 and VEGFA mRNA and protein were determined following trans- fection with inhibitor NC, miR-503 inhibitor and co- transfection of sh-LRIG2 and miR-503 ...
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Hypoxia upregulates angiogenesis and synovial cell migration in rheumatoid arthritis
... RA primarily affects the synovial lining, resulting in destructive changes to the joints and soft tissues, most commonly in the hand and wrist. Approximately 50% of patients with RA have tendon involvement, and ...
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25 Years On: A Retrospective on Migration Inhibitory Factor in Tumor Angiogenesis
... Twenty-five years ago marked the publication of the first report describing a functional contribution by the cytokine, macrophage migration inhibitory factor (MIF), to tumor-associated angiogenesis and ...
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Tumor treating fields inhibit glioblastoma cell migration, invasion and angiogenesis
... invasion, migration and angiogenesis via downregulation of PI3K/AKT/NF-κB ...reduced angiogenesis via decreased HIF1α, VEGF, MMP9 and MMP2 ...invasion, migration and angiogenesis are ...
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RERG suppresses cell proliferation, migration and angiogenesis through ERK/NF-κB signaling pathway in nasopharyngeal carcinoma
... cell migration and invasion molecules (MMP-2 and MMP- 9), and several pro-angiogenesis-related factors, such as vascular endothelial growth factor (VEGF), IL8 and IL6 in NPC ...
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Long non-coding RNA LINC01314 represses cell migration, invasion, and angiogenesis in gastric cancer via the Wnt/β-catenin signaling pathway by down-regulating KLK4
... inhibit angiogenesis in GC cells by negatively regulating the Wnt/β-catenin signaling ...cell migration and invasion in OSCC due to inactivation of the PI3K/AKT signaling pathway ...
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An efficient protocol to generate placental chorionic plate-derived mesenchymal stem cells with superior proliferative and immunomodulatory properties
... In addition to large quantities of MSCs, as required for clinical therapies, optimal quality is another cru- cial factor. A series of studies showed that fetal- derived MSCs isolated from the placenta have stron- ger ...
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Microglia enhanced the angiogenesis, migration and proliferation of co-cultured RMECs
... thelial angiogenesis and blood-brain barrier (BBB) dysfunction were caused by the soluble tumor necrosis factor α (TNF-α) released from microglial cells [59, ...
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Original Article Podoplanin increases migration and angiogenesis in malignant glioma
... were suspended in 50 µl medium and set on plastic petri wells, which were kept upside down in humid con- ditions. After 48 hours spheroids of identical size were harvested. For colla- gen gel assay a collagen (Cohesion, ...
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Coronary Serum Exosomes Derived from Patients with Myocardial Ischemia Regulate Angiogenesis through the miR-939-mediated Nitric Oxide Signaling Pathway
... Recently, a growing number of studies have suggested the key role of cell-to-cell communication in cardiac remodeling post MI. The surviving cardiac cells try to communicate with nearby or distant cells by sending ...
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DELTA-TOCOTRIENOL IS THE MOST BIOACTIVE ANTICANCER AGENT AGAINST GASTRIC CANCER
... proliferation, angiogenesis, invasion, and extravasation into liver and ...the migration as well as invasion of gastric cancer cells, likely limiting the process of metastasis in ...
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Anti-tumor effects of pigment epithelium-derived factor (PEDF): implication for cancer therapy. A mini-review
... around the neural retina and the central nervous system may denote a neurotrophic role of this receptor upon activation of PEDF. Moreover, upon PEDF binding, the PEDF-R N can potentially induce phospholipase A2 ...
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Icmt inhibition exerts anti-angiogenic and anti-hyperpermeability activities impeding malignant pleural effusion
... in angiogenesis, vascular permeability and tumor-associated inflammatory responses is relevant to the pathobiology of Malignant Pleural Effusion ...tumor angiogenesis in vivo and reduced endothelial cell ...
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Angiogenic potency evaluation of cell therapy candidates by a novel application of the in vitro aortic ring assay
... studying angiogenesis and evaluating the efficacy of potential new drugs and candi- date cell ...ideal angiogenesis assay must be ro- bust, rapid, reproducible and ...cell migration, proliferation ...
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Gemcitabine triggers angiogenesis-promoting molecular signals in pancreatic cancer cells: Therapeutic implications
... from migration and invasion assay demonstrate that Gem-CM-induced effect on HUVEC migration (Figure 6A) and invasion (Figure 6B) was significantly inhibited upon neutralization of IL-8 in ...
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Differential proteomics analysis of low- and high-grade of astrocytoma using iTRAQ quantification
... regulated in grade II/III/IV astrocytomas compared with grade I astrocytoma. To confirm the effect of fibulin-2 and -5, U251 cells, a typical glioma cell line, were transfected with the expression vectors of fibulin-2 ...
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<p>Characterization of Endothelial Cells Associated with Cerebral Arteriovenous Malformation</p>
... proliferation, migration and tube formation ...of angiogenesis involves the migration and proliferation of ECs, which can result in the growth of cAVM after ...of angiogenesis because it can ...
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Paired box 8 suppresses tumor angiogenesis and metastasis in gastric cancer through repression of FOXM1 via induction of microRNA-612
... cell migration and invasion, but had no significant impact on cell ...the migration and inva- sion of gastric cancer ...proliferation, migration, and invasion ...the migration and ...
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Molecular target based combinational therapeutic approaches in thyroid cancer
... mediate angiogenesis by secreting such growth factors that will bind to the re- spective receptors present on the endothelial cells result- ing in endothelial cell migration, proliferation and ...in ...
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