angiotensin I
Development and evaluation of an immuno-MALDI (iMALDI) assay for angiotensin I and the diagnosis of secondary hypertension
... decapeptide angiotensin-I (Ang-I) from angiotensinogen, an α-2 globulin constitu- tively manufactured by the ...the angiotensin-converting-enzyme (ACE), Ang-I is con- verted to ...
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Angiotensin-I converting enzyme (ACE-I) inhibitory and antiproliferative potential of chickpea seed protein hydrolysate
... decapeptide angiotensin-I into the potent vaso-constricting octapeptide angiotensin-II and also inactivates the potent vasodilator, bradykinin (Wu et ...
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Virtual screening for angiotensin I-converting enzyme inhibitory peptides from Phascolosoma esculenta
... important role in regulating the blood pressure [4]. ACE is a hypertension-responsible glycoprotein distributed in vascular endothelial, absorptive epithelial, and male germi- nal cells [5,6]. ACE cleaves the carboxyl ...
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ASSOCIATION OF ANGIOTENSIN I CONVERTING ENZYME INHIBITORS WITH THE ANGIOTENSIN II RECEPTORS ANTAGONISTS
... A different therapeutic strategy based on the combination of lower doses than recommended of an ACE inhibitor and an ARB has been suggested to effectively block the renin-angiotensin system without excessive ...
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ANGIOTENSIN I CONVERTING ENZYME GENE POLYMORPHISM IN PATIENTS WITH CHRONIC RENAL FAILURE
... The data presented in this study were the first to be reported in Iraq regarding the role of genetic variants of ACE gene in causation and progression of renal diseases. These findings clearly established the association ...
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Lack of differences in the expression of the angiotensin I - converting enzyme gene in the rotator muscles of patients with adolescent idiopathic scoliosis in a cross-sectional study comparing between the concave and convex sides of the scoliosis.
... type I fibers in the convexity of the scoliotic curve associated with loss of type II fibers in the concavity (Fidler et ...type I fibers, perimisial and endomysial fibrosis and fatty proliferation more ...
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Lack of angiotensin II–facilitated erythropoiesis causes anemia in angiotensin converting enzyme–deficient mice
... peptides angiotensin I and angiotensin II by radioimmunoassay (Figure 4, a and b, and Table ...determined angiotensin I and angiotensin II levels in the plasma of angiotensinogen ...
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Assessment of ACE A-240T Polymorphism with Chronic Kidney Disease in North Indian Population
... The angiotensin I converting enzyme gene I/D variation contributes to end-stage renal disease risk in Chinese patients with type 2 diabetes receiving ...
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Different frequencies of angiotensin converting enzyme genotypes in older hypertensive individuals
... The frequency of the D allele of an insertion/deletion (I/D) polymorphism of the angiotensin I-converting enzyme (ACE) gene has been reported to be elevated in myocardial infarction and other ...
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Effects of aqueous leaf extract of Asystasia gangetica on the blood pressure and heart rate in male spontaneously hypertensive Wistar rats
... Background: Asystasia gangentica (A. gangetica) belongs to the family Acanthaceae. It is used to treat hypertension, rheumatism, asthma, diabetes mellitus, and as an anthelmintic in South Africa, India, Cameroun, ...
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Journal of Applied Pharmaceutical Science
... an angiotensin receptor antagonist. Angiotensin II acts as a ...vasoconstriction, angiotensin II also stimulates the release of ...AT1 angiotensin II receptor. This binding prevents ...
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Contribution of genetic polymorphism in the renin angiotensin system to the development of renal complications in insulin dependent diabetes: Genetique de la Nephropathie Diabetique (GENEDIAB) study group
... by angiotensin II) can lead to elevated intraglomerular capillary pressure ...of angiotensin II can affect the development of diabetic ...of angiotensin I is low in the kidney (51), it has ...
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Angiotensin-converting enzyme I/D polymorphism in chronic obstructive pulmonary disease
... circulating) angiotensin converting enzyme plays an important role in the renin-an- giotensin-aldosterone-system (RAAS), which influ- ences circulatory homeostasis by salt and water reten- ...(insertion, I ...
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Prevalence of chronic kidney disease in diabetic adult out-patients in Tanzania
... CKD was almost ubiquitous among the Tanzanian adults with diabetes mellitus attending our clinic. More than 80% of patients had CKD and nearly 25% had an eGFR <60 ml/ min/1.73 m 2 . This highlights the importance of ...
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Global peak left atrial longitudinal strain assessed by transthoracic echocardiography is a good predictor of left atrial appendage thrombus in patients in sinus rhythm with heart failure and very low ejection fraction – an observational study
... ACE-I: Angiotensin- converting-enzyme inhibitors; AF: Atrial fibrillation; AHRE: Atrial high-rate epi- sodes; ARB: Angiotensin receptor blockers; AUC: Are under the ROC curve; BMI: Body mass index; ...
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Diagnosis and treatment of hereditary angioedema with normal C1 inhibitor
... ACE-I are commonly used for the treatment of hyper- tension and congestive heart failure. Recurrent angioe- dema as a complication of therapy with ACE-I is well described in the literature [15,16]. Most ...
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Effect of atrial peptides on aldosterone production
... angiotensin II in the rat in vivo. Atriopeptin I, II, and III decreased aldosterone release from zona glomerulosa cells in a dose-dependent fashion. 10 pM atriopeptin II inhibited basal aldosterone release ...
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Angiotensin Receptor Type I Blockade Inhibits Apoptosis in Meconium Instilled Rabbit Lungs
... quires the authocrine synthesis and proteolytic processing of angiotensinogen (AGT) to Angiotensin II (ANG II). In- hibitors of angiotensin converting enzyme (ACE) block meconium-induced apoptosis. ANG II ...
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Prevention of diabetes in hypertensive patients: Results and implications from the VALUE trial
... above, angiotensin II has an inhibitory effect on insulin-mediated PI3K activation, which is mainly mediated by activation of the angiotensin II type 1 (AT1) ...
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<p>Understanding the early mortality benefit observed in the PARADIGM-HF trial: considerations for the management of heart failure with sacubitril/valsartan</p>
... Even among patients receiving standard-of-care manage- ment, HFrEF continues to be associated with high rates of mortality, as the disease typically progresses despite treatment. 2,37,38 The number of deaths attributable ...
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