Angiotensin I converting enzyme
Male accessory glands of Drosophila melanogaster make a secreted angiotensin I converting enzyme (ANCE), suggesting a role for the peptide processing enzyme in seminal fluid
... the enzyme responsible for the removal of a C-terminal dipeptide (His-Leu) from the decapeptide angiotensin I to generate the vasopressor octopeptide angiotensin II; hence its common name ...
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Virtual screening for angiotensin I-converting enzyme inhibitory peptides from Phascolosoma esculenta
... Background: Many short peptides have proved to exhibit potential anti-hypertensive activity through the inhibition of the Angiotensin I-converting enzyme (ACE) activity and the regulation of ...
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An insertion/deletion polymorphism in the angiotensin I converting enzyme gene accounting for half the variance of serum enzyme levels
... A polymorphism consisting of the presence or absence of a 250-bp DNA fragment was detected within the angiotensin I-converting enzyme gene (ACE) using the endothelial ACE cDNA probe. This ...
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Production of Angiotensin-I-Converting Enzyme inhibitory peptide from goat milk casein: optimization conditions of complex protease hydrolysate by response surface methodology and purification
... of angiotensin- I-converting enzyme (ACE, peptidyldipeptide hydrolase, ...transforming angiotensin I type into II type, then deactivates the depressor bradykinin to lose ...
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Angiotensin-I converting enzyme (ACE-I) inhibitory and antiproliferative potential of chickpea seed protein hydrolysate
... Rabbit lungs as donated by the pharmacology laboratory of Defence Research & Development Establishment (DRDE), Gwalior Madhya Pradesh state of India, was used to obtain an angiotensin converting ...
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ANGIOTENSIN I CONVERTING ENZYME GENE POLYMORPHISM IN PATIENTS WITH CHRONIC RENAL FAILURE
... for the development of ESRD. [2, 3] On the other hand, the prevalence of hypertension increases with decreasing renal function. These results from both decreased sodium excretion and an activation of the ...
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ASSOCIATION OF ANGIOTENSIN I CONVERTING ENZYME INHIBITORS WITH THE ANGIOTENSIN II RECEPTORS ANTAGONISTS
... the angiotensin- converting enzyme inhibitors are well known mainly in the hypertension and heart failure treatment ...the angiotensin II formation suggesting the involvement of alternative ...
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Extraction and isolation of anti-hypertensive peptide by alkalase from spirulina platensis
... Spirulina has attracted a great attention as it contains many nutrients, such as protein, vitamins and minerals. Spirulina contains peptides that have therapeutic and beneficial effects on the human body. Some medicinal ...
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Effects of aqueous leaf extract of Asystasia gangetica on the blood pressure and heart rate in male spontaneously hypertensive Wistar rats
... Background: Asystasia gangentica (A. gangetica) belongs to the family Acanthaceae. It is used to treat hypertension, rheumatism, asthma, diabetes mellitus, and as an anthelmintic in South Africa, India, Cameroun, ...
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Different frequencies of angiotensin converting enzyme genotypes in older hypertensive individuals
... The frequency of the D allele of an insertion/deletion (I/D) polymorphism of the angiotensin I-converting enzyme (ACE) gene has been reported to be elevated in myocardial infarction and ...
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Assessment of adverse drug reactions of angiotensin converting enzyme (ace) inhibitors and angiotensin receptor blockers (arbs) among sudanese patients
... type I diabetes, blocking the RAS with angiotensin converting enzyme (ACE) inhibitors prevents progression from micro albuminuria to overt nephropathy, and in overt nephropathy decreases the ...
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Comparing the effect of Angiotensin-Converting Enzyme Inhibitors versus Angiotensin Receptor Blockers in heart failure patients with type 2 diabetes mellitus: a systematic review
... However, that study does not distinguish between patients with comorbid DM and non-DM. In heart failure patients with T2DM, diabetes may be the primary cause of cardiac dysfunction and in others, it may play a more ...
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Angiotensin-converting enzyme I/D polymorphism in chronic obstructive pulmonary disease
... circulating) angiotensin converting enzyme plays an important role in the renin-an- giotensin-aldosterone-system (RAAS), which influ- ences circulatory homeostasis by salt and water reten- ...
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Cumulative fluid accumulation is associated with the development of acute kidney injury and non recovery of renal function: a retrospective analysis
... ACE-I: Angiotensin converting enzyme inhibitor; ARB: Angiotensin receptor blocker; AKI: Acute kidney injury; BMI: Body mass index; BW: Body weight; CI: Confidence interval; CKD: Chronic ...
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Early onset of graft glomerulopathy in a patient with post-transplant diabetes mellitus after renal transplantation: a case report
... ACE-I: Angiotensin-Converting Enzyme Inhibitors; ADA: American Diabetes Association; ARBs: Angiotensin II Receptor Blockers; BMI: Body Mass Index; CNI: Calcineurin Inhibitors; CyA: ...
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A pilot clinical trial of recombinant human angiotensin converting enzyme 2 in acute respiratory distress syndrome
... RAS signaling and ACE2 have been implicated in the pathogenesis of acute respiratory distress syndrome (ARDS). Mice deficient in ACE2 developed severe acute lung injury (ALI) following challenge with a variety of insults ...
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Can the onset of heart failure be delayed by treating diabetic cardiomyopathy?
... ACE‑I: angiotensin‑converting‑enzyme inhibitor; ARBs: angiotensin recep‑ tor blockers; AF: atrial fibrillation; BITA: bilateral internal thoracic arteries; CABG: coronary artery by‑pass ...
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Mechanical effects of left ventricular midwall fibrosis in non ischemic cardiomyopathy
... Abbreviations ACE-I: angiotensin-converting enzyme inhibitors; ARB: angiotensin receptor blockers; CMR: cardiovascular magnetic resonance; DSR: diastolic strain rate; Ɛ: strain; FT: feat[r] ...
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Association of anaemia in primary care patients with chronic kidney disease: cross sectional study of quality improvement in chronic kidney disease (QICKD) trial data
... Anaemia is an independent risk marker for cardiovascular morbidity and mortality and it is a common complication in patients with chronic kidney disease (CKD) [1-3]. CKD is divided into stages 1 to 5, with stage 3 ...
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Vitamin D receptor activation reduces inflammatory cytokines and plasma MicroRNAs in moderate chronic kidney disease – a randomized trial
... ACE-I: Angiotensin converting enzyme inhibitor; ARB: Angiotensin receptor blocker; b-FGF: Basic fibroblast growth factor; CKD: Chronic kidney disease; CVD: Cardiovascular diseases; ...
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