Angiotensinogen gene
Molecular mechanism of transcriptional activation of angiotensinogen gene by proximal promoter
... acetyltransferase (CAT) assays with 5'-deleted constructs showed that the proximal promoter region from -96 to +22 of the transcriptional start site was enough to express HepG2-specific CAT activity. Electrophoretic ...
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Linkage of the angiotensinogen gene locus to human essential hypertension in African Caribbeans
... angiotensinogen gene which encodes the key substrate within this system has been linked to essential hypertension in White ...the angiotensinogen gene to essential hypertension in African ...
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Polymorphism in miR-31 and miR-584 binding site in the angiotensinogen gene differentially influences body fat distribution in both sexes
... that angiotensinogen is differentially expressed in both sexes and in different parts of the ...in angiotensinogen production by adipocytes (Dusserre et ...in angiotensinogen expression have been ...
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Association of angiotensinogen gene T235 variant with progression of immunoglobin A nephropathy in Caucasian patients
... of angiotensinogen gene copies ...plasma angiotensinogen concentrations, support the above hypothesis ...the angiotensinogen T235 variant might be a risk factor for progressive IgA nephropathy ...
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Angiotensinogen gene and hypertension in Chinese
... the angiotensinogen gene, which encodes the key substrate for renin within this system, has been reported linked to and associated with essential hyper- tension in White Europeans, African-Caribbeans, and ...
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Effect of dietary protein on rat renin and angiotensinogen gene expression
... Plasma renin activity varies with the level of dietary protein, being higher on a high protein diet. To explore the molecular mechanisms underlying this relationship we first examined the effect of dietary protein on ...
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Association of angiotensinogen gene SNPs and haplotypes with risk of hypertension in eastern Indian population
... AGT: Angiotensinogen; Ang II: Angiotensin II; BMI: Body mass index; BUN: Blood urea nitrogen; CEBP: Enhancer binding protein; CI: Confidence interval; CpG: Cytosine-guanine dinucleotides; DBP: Diastolic blood ...
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Simultaneous Genotyping of the Rs4762 and Rs699 Polymor-phisms in Angiotensinogen Gene and Correlation with Iranian CAD Patients with Novel Hexa-primer ARMS-PCR
... Background: A significant role of Renin-angiotensin system (RAS) genetic variants in the pathogenesis of essential hypertension and cardiovascular diseases has been proved. This study aimed to develop a new, fast and ...
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The serum angiotensinogen concentration and variants of the angiotensinogen gene in white and black children
... for angiotensinogen to contribute to racial differences in blood pressure in a study of 148 white and 62 black normotensive children (mean age, ...mean angiotensinogen level was 19% higher in blacks than in ...
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Angiotensinogen gene is expressed and differentially regulated in multiple tissues of the rat
... Northern blot analysis demonstrated angiotensinogen mRNA in RNA extracted from liver, aorta, mesentery, atria, kidney, brain, spinal cord, large intestine, adrenal, and lung Figs.. For a[r] ...
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Association between Angiotensinogen M235T Polymorphism and Preeclampsia in Iranian Pregnant Women.
... However, this is a preliminary study and requires more hypertensive and normotensive pregnant women to be comparatively studied in order to improve the statistical significance. In conclusion, our findings is in line ...
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Angiotensinogen T235 expression is elevated in decidual spiral arteries
... RT-PCR. We selected primers designed from angiotensinogen exon 2:AGT-Ex2, 5 9 ACT TCA CAG AAC TGG ATG TTG CTG C 3 9 ; and exon 3: AGT-Ex3, 5 9 AAC AGA CAC TGA GGT GCT GTT GTC CAC 3 9 . These primers flank intron 2 ...
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Urinary angiotensinogen is a marker for tubular injuries in patients with type 2 diabetes
... and angiotensinogen levels was also found both in microalbuminuria and microalbuminuria stages; however, ACR did not show significant correla- tion with urinary angiotensinogen at normo-, micro-, and ...
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Original Article Increased urinary angiotensinogen precedes the onset of albuminuria in normotensive type 2 diabetic patients
... [7] Yamamoto T, Nakagawa T, Suzuki H, Ohashi N, Fukasawa H, Fujigaki Y, Kato A, Nakamura Y, Suzuki F and Hishida A. Urinary angiotensino- gen as a marker of intrarenal angiotensin II activity associated with ...
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A local renal renin–angiotensin system activation via renal uptake of prorenin and angiotensinogen in diabetic rats
... human angiotensinogen expression (brown color staining in A–D) in podocytes (arrows), proximal tubules (P), *macula densa and the distal nephron (DT) including collecting ducts and endothelial cells of renal small ...
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Analysis of renin-angiotensin aldosterone system gene polymorphisms in malaysian essential hypertensive and type 2 diabetic subjects
... Hypertension is an extremely common co-morbidity of diabetes and affects 70% of patients with diabetes and is approximately twice as common in persons with diabetes as in those without diabetes [21]. Several ...
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Androgen regulation of rat renal angiotensinogen messenger RNA expression
... Renal angiotensinogen (ang-n) mRNA concentration in the male WKY rat increases significantly during ...renal angiotensinogen mRNA level in the adult female WKY rat is considerably lower than in the ...
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Evaluation of G2350A Polymorphism of the Angiotensin-Converting Enzyme (ACE) Gene in Chronic Kidney Disease
... polymorphisms (I/D, G2350A and A–240T) in ACE gene with the risk of CKD, but the results were inconsistent and contradictory. In this regard, the association based studies have indicated that ACE I/D polymorphism ...
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HDAC9 is an epigenetic repressor of kidney angiotensinogen establishing a sex difference
... Importantly, gene suppression of HDAC9 con- comitantly augmented AGT mRNA and protein levels in cultured PTC, indicating that HDAC9 is a repressor of AGT in ...
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Localization and differential regulation of angiotensinogen mRNA expression in the vessel wall
... contrast, angiotensinogen mRNA level in the periaortic fat is not influenced by sodium ...of angiotensinogen mRNA levels in the blood vessel wall by ...
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