Annexin A1
Original Article Association of nuclear annexin A1 with prognosis of patients with esophageal squamous cell carcinoma
... [5-11]. Annexin A1 (ANXA1), the first characterized member of the annexin superfamily, is an intracellular protein which is aberrantly expressed in many types of cancer, such as gastric [6, 9, 12], ...
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Annexin A1–containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair
... endogenous annexin A1 (ANXA1) is released as a component of extracellular vesicles (EVs) derived from intestinal epithelial cells, and these ANXA1-containing EVs activate wound repair ...
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Upregulation of Hsp90-beta and annexin A1 correlates with poor survival and lymphatic metastasis in lung cancer patients
... BA0930, Bostere Biotech Company, Wuhan, China) and the rabbit anti-human annexin A1 (1:100 dilution; Product Code: 55018-1-AP, ProteinTech Group, Inc., USA). The kit provided positive slices that served as ...
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Efficient Reovirus- and Measles Virus-Mediated Pore Expansion during Syncytium Formation Is Dependent on Annexin A1 and Intracellular Calcium
... of annexin A1 (AX1) expression dramatically reduced both reptilian reovirus p14 and measles virus F and H protein-mediated pore expansion during syncytiogenesis but had no effect on pore ...
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The anti-inflammatory Annexin A1 induces the clearance and degradation of the amyloid-β peptide
... Amyloid- β (A β ) peptide is present in high levels in the brains of Alzheimer ’ s disease (AD) patients and is closely associated with the pathogenesis of the disease. A β pep- tides are toxic products derived from the ...
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Increased annexin A1 and A2 levels in bronchoalveolar lavage fluid are associated with resistance to respiratory disease in beef calves
... for annexin A1, or 40 μg of total protein for annexin A2, were incubated for 5 min at 95°C in SDS loading buffer containing 65 mM DTT, then separated on a 12% SDS gel using 100 V for 90 ...
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Annexin A1 in plasma from patients with bronchial asthma: its association with lung function
... Plasma ANXA1 levels in asthmatic patients (0.570 ± 0.043 ng/ml) were higher than those in healthy control subjects (0.312 ± 0.078 ng/ml; Interquartile range, IQR: 0.0–0.611), (p < 0.01) (Fig. 1a). Plasma ANXA1 levels ...
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Annexin A1 sustains tumor metabolism and cellular proliferation upon stable loss of HIF1A
... of annexin A1 (ANXA1) for growth of HIF-1α-deficient ...the annexin protein family, named after their ability to annex to phospholipids in the cell membrane ...
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Annexin A1 expression in a pooled breast cancer series: association with tumor subtypes and prognosis
... ANXA1: Annexin A1; BCAC: Breast Cancer Association Consortium; BCSS: Breast cancer-specific survival; CC1: Cell Conditioning 1; CFMPB: Core Facility Molecular Pathology and Biobanking; ChaK1: Channel kinase ...
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Recurrent duplications of the annexin A1 gene (ANXA1) in autism spectrum disorders
... Annexin A1, a member of the annexin superfamily that contains 13 calcium or calcium and phospholipid- binding proteins, has been implicated in many diverse cellular functions, including ...
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Analysis of lymphocytes in patients with Plasmodium vivax malaria and its relation to the annexin A1 and IL 10
... [13,14]. Annexin-A1 (ANXA1) is an endogenous protein with anti-inflammatory functions, endowed with potent anti- migratory activity of neutrophils, ensuring the transitory nature of the inflammatory ...
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Original Article Myenteric denervation in gastric carcinogenesis: differential modulation of nitric oxide and annexin-A1
... and annexin-A1 (ANXA1) and determined how they can be exploited in the N-methyl-N-nitro-N-nitrosoguanidine (MNNG)-induced gastric car- cinogenesis and myenteric denervation ...with annexin-A1 ...
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Annexin-A1 peptide down-regulates the leukocyte recruitment and up-regulates interleukin-10 release into lung after intestinal ischemia-reperfusion in mice
... protein annexin-A1 (ANXA1) is a potent mediator of inflammation resolution and a 37-kDa member of the annexin family of calcium and phospholipid-binding proteins, expressed constitutively in many ...
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Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair
... N-formyl peptide receptors (FPRs) are critical regulators of host defense in phagocytes and are also expressed in epithelia. FPR signaling and function have been extensively studied in phagocytes, yet their functional ...
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<p>Advancements of Annexin A1 in inflammation and tumorigenesis</p>
... of Annexin A1 was analyzed from 1,072 Chinese gastric cancer patients using immunohistochemis- try, which showed that complete loss of Annexin A1 expression was observed in 691 (64%) of the ...
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Annexin A1 is elevated in patients with COPD and affects lung fibroblast function
... First, Annexin A1 significantly upregulated pro- liferation in fibroblasts obtained from nonsmokers, smokers without COPD, and smokers with ...of Annexin A1 on collagen production in lung ...
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Modulation of experimental autoimmune encephalomyelitis by endogenous Annexin A1
... [4,5]. Annexin A1 (AnxA1), previously known as lipocortin-1, was originally identified as a phospholipase A2 (PLA2)- inhibitory protein and second messenger of glucocorti- coid pharmacological effects ...
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The restorative role of annexin A1 at the blood–brain barrier
... ANXA1: annexin A1; BBB: blood–brain barrier; BCRP: breast cancer resistance protein; CNS: central nerv- ous system; COX2: cyclooxygenase 2; CSF: cerebrospinal fluid; DM: diabetes mellitus; DPN: ...
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Annexin A1 is involved in the acquisition and maintenance of a stem cell-like/aggressive phenotype in prostate cancer cells with acquired resistance to zoledronic acid
... of annexin A1 (ANXA1) in the acquisition and maintenance of stem-like/aggressive features in prostate cancer (PCa) cells comparing zoledronic acid (ZA)-resistant DU145R80 with their parental DU145 ...
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Defective formyl peptide receptor 2/3 and annexin A1 expressions associated with M2a polarization of blood immune cells in patients with chronic obstructive pulmonary disease
... collagen production in the underlying lung fibroblasts and may contribute to small airway remodeling in COPD [10]. In contrast, decreased levels of LXA4 and annexin A1 (ANXA1) have been found in pediatric ...
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