anti-Alzheimer
Ginger components as new leads for the design and development of novel multi-targeted anti-Alzheimer’s drugs: a computational investigation
... Abstract: Ginger (Zingiber officinale), despite being a common dietary adjunct that contributes to the taste and flavor of foods, is well known to contain a number of potentially bioactive phytochemicals having valuable ...
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ANTI ALZHEIMER ACTIVITY OF TACRINE LOADED METHOXYPOLY (ETHYLENE GLYCOL) POLY (CAPROLACTONE) NANOPARTICLES
... Vol 11, Special Issue 4, 2018 Online 2455 3891 Print 0974 2441 ANTI ALZHEIMER ACTIVITY OF TACRINE LOADED METHOXYPOLY (ETHYLENE GLYCOL) POLY (CAPROLACTONE) NANOPARTICLES FELIX JOE V1*, SATHESH KUMAR S2[.] ...
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QSAR study of 5,6 bicyclic heterocycles analogues as anti Alzheimer’s agents using the statistical analysis methods
... In this study, three different modelling methods, MLR, MNLR and ANN were used in the construction of a QSAR model for the anti-Alzheimer agents and the resulting models were compared. It was shown the ...
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Anti-Alzheimer Activity of Hydroalcoholic Extract of Butea monosperma leaves
... The present study investigated the Anti-Alzheimer activity of hydroalcholic extract of Butea monnosperma leaves in rats models. Progressive neurodegeneration in the brain, leading to the depletion of ...
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In silico adme and biological activity assessment of natural phytoconstituents for anti alzheimer potential
... Phytoconstituents such as, Wedalolactone Demethylwedalolactone, Valeranone, Jatamansin, Gamma gurjunene, beta-caryophyllene alpha humulin, Oleic acid, Palmitic acid, Linoleic acid, Gallic acid, Ellagic acid, Withafirin ...
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Antioxidant, Anti-alzheimer and Anti-parkinson activity of Artemisia nilagirica Leaves with Flowering Tops
... anxiety, Alzheimer‟s disease and Parkinson‟s ...antioxidant, anti-alzheimer and anti-parkinson activity of Artemisia nilagirica leaves with flowering tops ...the anti-alzheimer's ...
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“Anti-Alzheimer Potential of Green Moong Bean” by Sushila Kaura, Milind Parle, India .
... cell apoptosis, reduction in beta amyloid accumulation, enhancing neurogenesis and cognitive function. 30 Estrogen levels can be restored naturally by consuming phytoestrogens. Moong bean sprouts possess phytoestrogens ...
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ANTI-ALZHEIMER POTENTIAL OF ORANGE JUICE
... In the present study, orange juice when administered orally to mice for 10 consecutive days showed remarkable improvement in memory scores in various experimental models. This memory enhancing effect shown by orange ...
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VIRTUAL SCREENING OF PHYTOCHEMICALS OF MORINDA CITRIFOLIA AS ANTI INFLAMMATORY AND ANTI ALZHEIMER AGENTS USING MOLEGRO VIRTUAL DOCKER ON p38 α MITOGEN ACTIVATED PROTEIN KINASE ENZYME
... Anti-inflammatory and neuroprotective actions of Morinda citrifolia The M. citrifolia plant is one of approximately 11,000 species of the family Rubiaceae. Furthermore known as the Indian mulberry, BaJiTian, ...
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... has anti-Alzheimer properties against D-Galactose induced Alzheimer’s disease since it resulted in body weight gain and organ index, improved the behavioural activity and learning skills through elevation ...
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Preparation, characterization, and in vivo evaluation of intranasally administered liposomal formulation of donepezil
... Abstract: The adequate amount of drug delivery to the brain in neurological patients is a major problem faced by the physicians. Recent studies suggested that intranasal administra- tion of liposomal formulation may ...
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Dominantly Inherited Alzheimer Network: facilitating research and clinical trials
... The DIAN-TU design leverages the existing infrastruc- ture of the ongoing DIAN longitudinal study and builds upon important DIAN baseline and rate-of-change data. The trial was designed as a randomized, blinded, placebo- ...
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HAEMATOCOCCUS PLUVIALIS EXTRACT PROMOTING THE RECOVERY OF MEMORY IMPAIRMENT IN ALZHEIMER'S RATS: ANTI INFLAMMATORY AND ANTIAPOPTOTIC EFFECTS
... It is well known that oxidative damage affects the central nervous system (CNS) and is significantly assumed to induct Alzheimer’s pathogenesis [1]. The reasons of occurrence of these diseases because the brain of human ...
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Centiloid cut-off values for optimal agreement between PET and CSF core AD biomarkers
... AD: Alzheimer ’ s disease; ADNC: AD neuropathologic change; ADNI: Alzheimer ’ s Disease Neuroimaging Initiative; ALFA: Alzheimer and Families; AUC: Area under the curve; A β : β -Amyloid; CERAD: ...
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Alzheimer diseaseAbout preclinical Alzheimer diseaseBefore the diagnosis
... PRECLINICAL ALZHEIMER DISEASE? In the same way that some cancers can grow for a long time before the person shows symptoms, scientists think that people can have Alzheimer disease (AD) for a long time even ...
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Perspectives on future Alzheimer therapies: amyloid-β protofibrils - a new target for immunotherapy with BAN2401 in Alzheimer’s disease
... for Alzheimer ’ s disease (AD) have no effect on disease progression, and this creates a large unmet medical ...first anti-amyloid-beta (anti-A β ) vaccine developed by Elan, AN1792, was halted in ...
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Cognitive reserve and clinical progression in Alzheimer diseaseA paradoxical relationship
... Data collection and sharing for this project was funded by the Alzheimer's Disease Neuroimaging Initiative (ADNI) (Na- tional Institutes of Health Grant U01 AG024904) and DOD ADNI (Department of Defense award number ...
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Cognitive and imaging markers in non-demented subjects attending a memory clinic: study design and baseline findings of the MEMENTO cohort
... or anti-diabetic drug intake of glycaemia > 7 mmol/L), hypertension (anti-hypertensive drug intake or mean of three blood pressure measurements either ≥ 140 mmHg for systolic blood pressure or ≥ 90 mmHg ...
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Antibodies against phosphorylcholine are not altered in plasma of patients with Alzheimer’s disease
... Anti-PC levels were quantified in plasma diluted 1:101 in accordance with the manufacturer’ s recommendations using CVDefine (Athera Biotechnologies, Stockholm, Sweden), an indirect, noncompetitive, enzyme ...
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For debate: substituting placebo controls in long-term Alzheimer's prevention trials
... If supported by further evidence, where in the clinical development process of a new compound aimed at sec- ondary prevention of dementia due to AD could be the place for the proposed PGSA? No doubt some of the earlier ...
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