Anti-CCP
Evaluation of anti ccp for early diagnosis and assessment of disease severity in rheumatoid arthritis patients
... induce anti citrullinated protein antibodies (ACPA) locally produced by plasma cell (Van Venrooij, ...disease. Anti-CCP antibody has proven useful in identifying those patients who are likely to have ...
5
Use and Significance of Anti CCP Antibodies in Rheumatoid Arthritis.
... RA is associated with only a few specific auto antibodies, including APF, AKA and anti-CCP and several less specific auto antibodies including RF 4 . Despite a well-documented lack of specificity, RF ...
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Anti-type II collagen antibodies, anti-CCP, IgA RF and IgM RF are associated with joint damage, assessed eight years after onset of juvenile idiopathic arthritis (JIA)
... Limitations of our study were the small number of autoantibody-positive patients, and that no data on radiological damage was available for assessment of joint damage. The JADI-A index used in this study is vali- dated ...
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Adjusting for sex and anti CCP levels in linkage analysis of rheumatoid arthritis
... like anti-CCP, which is known to be biologically involved in RA, some regions that are likely related to anti-CCP could be identified (on chromosomes 1, 9, 10, and ...of anti-CCP ...
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Clinical correlations with Porphyromonas gingivalis antibody responses in patients with early rheumatoid arthritis
... [6]. CCP anti- bodies are associated with a more aggressive course [7] and may be detected prior to the onset of clinical disease [8], suggesting a role in RA ...
12
Proteomic analysis of saliva: a unique tool to distinguish primary Sjögren's syndrome from secondary Sjögren's syndrome and other sicca syndromes
... Scl-70, anti-cyc- lic citrullinated peptide ...immunofluorescence, anti Ro/SSA, La/SSB antibodies by controimmunoelectrophoresis, rheumatoid factor by nephelometry and anti-CCP by ...
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Total calcium sensing receptor expression in circulating monocytes is increased in rheumatoid arthritis patients with severe coronary artery calcification
... was determined by a chemiluminometric immunoassay (Liaison N-tact PTH CLIA; Diasorin, Stillwater, MN, USA). Serum 25 OH vitamin D level was determined (LIAISON™ 25 OH Vitamin D Total Assay; Diasorin). Corrected calcium ...
9
The PTPN221858C/T polymorphism is associated with anti cyclic citrullinated peptide antibody positive early rheumatoid arthritis in northern Sweden
... with anti-CCP ...and anti-CCP antibodies, whereas HLA-SE was strongly associated with anti-CCP ...of anti-CCP antibody-positive patients after disease onset was ...
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Role of anti cyclic citrullinated peptide antibodies in discriminating patients with rheumatoid arthritis from patients with chronic hepatitis C infection associated polyarticular involvement
... of anti-cyclic citrullinated peptide (anti-CCP) antibodies in distinguishing between patients with rheumatoid arthritis (RA) and patients with polyarticular involvement associated with chronic ...
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Citrullinated fibronectin inhibits apoptosis and promotes the secretion of pro inflammatory cytokines in fibroblast like synoviocytes in rheumatoid arthritis
... Anti-cyclic citrullinated protein (anti-CCP) antibodies belong to the family of anti-fillagrin autoantibodies [2]. Anti-CCP antibodies are produced locally in the syno- vium of ...
9
Nonspecific interstitial pneumonia: clinical associations and outcomes
... of anti-Sjogren's syndrome antigen A (SSA) or anti-Sjogren's syndrome antigen B (SSB), anti-Scl-70, anti-Sm, anti-Jo-1, anti-ribonucleoprotein antibody (anti-RNP), ...
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Presence of antibodies against cyclic citrullinated peptides in patients with 'rhupus': a cross sectional study
... for anti-CCP antibodies, rheumatoid factor, antinuclear antibodies, anti-extractable nuclear antigens, and antibodies against double-stranded DNA ...
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Routine use of Zenit RA, a novel chemiluminescent immunoanalyzer in autoimmune disease diagnosis
... reported, anti-CCP antibodies are sensitive and highly specific markers for RA [6], especially in early stage [7, ...low anti-CCP antibodies titers (from 33 until 60 U/ mL) were not detected ...
5
Significant association between joint ultrasonographic parameters and synovial inflammatory factors in rheumatoid arthritis
... (RF), anti-cyclic citrullinated peptide antibody (anti-CCP), and mean disease activity score using the 28-joint disease activity score/erythrocyte sedimentation rate ...disease-modifying anti- ...
8
Original Article An updated meta-analysis of association of rheumatoid arthritis related interstitial lung disease with anti-cyclic citrullinated peptide antibody or rheumatoid factor
... positive anti-CCP antibodies and/or RF in the RA-ILD group are significantly higher than those in the RA-only group [12, 18, 21, ...of anti-CCP antibodies for RA suggested that ...
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Lack of replication of interactions between polymorphisms in rheumatoid arthritis susceptibility: case–control study
... Introduction: Approximately 100 loci have been definitively associated with rheumatoid arthritis (RA) susceptibility. However, they explain only a fraction of RA heritability. Interactions between polymorphisms could ...
10
Circulating secretory IgA antibodies against cyclic citrullinated peptides in early rheumatoid arthritis associate with inflammatory activity and smoking
... IgA anti-CCP antibodies in TIRA-1 were analyzed by ELISAs as previously described [6, 40] and in TIRA-2 by ELISA for IgG anti-CCP (CCPlus® Immunoscan) and by fluorescence enzyme immunoassays ...
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Disease Activity, Oxidized-LDL Fraction and Anti-Oxidized LDL Antibodies Influence Cardiovascular Risk in Rheumatoid Arthritis
... Results. Both SCORE and oxLDL fraction were elevated in RA patients as compared to the healthy controls (3.1 ± 3.7 vs. 0.8 ± 1.2, p = 0.005; and 0.029 ± 0.033% vs. 0.014 ± 0.006%, p = 0.04, respectively). In the RA ...
8
Diagnostic value of anti cyclic citrullinated peptide antibodies in Greek patients with rheumatoid arthritis
... Serum samples from patients and controls were kept at - 80°C until tested. Anti-CCP antibodies were detected using the QUANTA lite CCP2 IgG ELISA kit (INOVA diag- nostics, San Diego CA). The assay was ...
7
Does the nitrogen single breath washout test contribute to detecting pulmonary involvement in rheumatoid arthritis? A pilot study
... and anti-cyclic citrullinated pep- tide (anti-CCP) ...and anti-CCP (immunofluorometric assay; Thermo Fisher ImmunoCAP Assays) were ≥ 8 IU/mL and > 10 EliA U/mL, ...
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