anti-estrogenic
Potential anti-inflammatory, anti-adhesive, anti/estrogenic, and angiotensin-converting enzyme inhibitory activities of anthocyanins and their gut metabolites
... the anti- proliferative effect shown in the MCF-7 cell model: hydrogen bonds between hydroxyl groups and His524 (ERb His475) and Arg394-Glu353 (ERb Arg346-Glu305) ...higher estrogenic/anti- ...
12
Cytotoxic, Cytostatic and Anti-Estrogenic Effect of Thymoquinone on Estrogen Receptor-Positive Breast Cancer MCF7 Cell Line
... as anti-cancer in breast and ovarian adenocarcinoma [17], colorectal cancer [18], human pancreatic adenocarcinoma [19, 20], lung carcinoma [21], uterine sarcoma [19], neoplastic keratinocytes [22], human ...
8
Estrogen receptor beta sensitizes breast cancer cells to the anti estrogenic actions of endoxifen
... responsiveness of endocrine sensitive tumors to hormo- nal agents. Following the discovery of ERb, investigators have sought to uncover the role that this protein may play in mediating breast cancer progression and ...
13
Combined estrogenic and anti-estrogenic properties of estetrol on breast cancer may provide a safe therapeutic window for the treatment of menopausal symptoms
... Increased risk of breast cancer is a critical side effect associated with the use of a menopausal hormone therapy (MHT). Estetrol (E4) is a natural estrogen produced by the human fetal liver and is a promising compound ...
16
Polybrominated diphenyl ethers: levels in Townsville sediments, depuration and (anti-)estrogenic effects in Barramundi (Lates calcarifer)
... The purpose of this research was to study polybrominated diphenyl ethers (PBDEs) and the effect they have in North Queensland, Australia, specifically in reference to a commercially important fish species, barramundi ...
17
Polybrominated diphenyl ethers: levels in Townsville sediments, depuration and (anti-)estrogenic effects in Barramundi (Lates calcarifer)
... polyclonal anti-Vtg antibodies available from Biosense ...mouse anti-striped bass Vtg monoclonal primary antibody, ND-3G2 (ND-3G2) (Biosense Laboratories, Norway), had the highest binding affinity in ...
116
The effects of Sutaehwan Gami on menopausal symptoms induced by ovariectomy in rats
... uterine weight was due to an atrophy of endometrium resulting from a lack of hormones secreted by the ovar- ies. Black et al . [18] have described further evidence of reduced uterine weight by the reduction of uterine ...
8
Anti-androgenic, anti-oestrogenic and antioxidant activities of aqueous extract of Laportea ovalifolia on adults rats.
... steroid anti- estrogen) treatment is associated with increased serum estradiol in healthy middle-aged ...of anti-estrogenic substances that act as ...
10
Assessment of xenoestrogenic exposure by a biomarker approach: application of the E-Screen bioassay to determine estrogenic response of serum extracts
... an estrogenic response (Figure ...weak anti-estrogenic effect, since the proliferative effect of treatment with 10 pM E2 was reduced when compared to that of treatment with 10 pM E2 alone (Figure ...
14
EXPERIMENTAL AND CLINICAL EVALUATION OF CONTRACEPTIVE AGENTS
... their estrogenic, anti- estrogenic, progestational, anti-progestational, anti-ovulatory and anti- implantation activity in various animal ...or anti-androgenic activity by ...
10
Pharmacological Evaluation and Antifertility Activity of Aloe barbadensis Linn on female wistar rats.
... of estrogenic and anti-estrogenic activity associated with hormonal level and histological parameter like uterine weight, diameter of uterus, thickness of endometrium and height of endometrium ...
8
Antifertility Activity of Root Bark of Caesalpinia Bonduc Linn. Roxb.in Female Albino Rats
... Caesalpinia bonduc L., commonly known as Nata Karanja, a prickly shrub found throughout the hotter parts of India, Myanmar and Sri Lanka, has grey, hard, globular shaped seeds with a smooth shining surface. Seeds consist ...
8
Lupinalbin A as the most potent estrogen receptor α and aryl hydrocarbon receptor agonist in Eriosema laurentii de Wild (Leguminosae)
... and anti-tumorigenic rele- vance. However, besides these anti-estrogenic effects of AhR, data in literature are quite conflicting regarding the implication of AhR in cancer promotion or ...
10
ANTIESTROGENIC EFFECT OF TUBER EXTRACT OF CYPERUS ROTUNDUS L. ON THE ENDOMETRIAL THICKNESS OF MICE (MUS MUSCULUS L.)
... and ovarium hormones, such progesterone, the most essential for implantation and pregnancy of all mammals, as well as the specific estrogen hormones. [12, 4] In this study, tuber extract of C. rotundus showed ...
7
“Screening of Plants for Rodent Control: Review” by JK Roop, India.
... So, estrogenic (phytoestrogens) and anti-estrogenic compounds present in the plant extracts can affect the circulating levels of hormones and pituitary gonadotropins and can cause fertility ...
12
The effect of estrogenic compounds on psychosis-like behaviour in female rats
... Given that dopamine is the common primary neurotransmitter target of apomorphine and methamphetamine, it is likely that dopaminergic mechanisms are mediating the effects of 17β and TAM. Using the same chronic treatment ...
14
More Stable, More Estrogenic: The SERM ERα LBD Complex
... Molecular mechanics based computations in solution were used to gain insight into the effects on the receptor caused by the stereochemistry of the side chain. Uncon- strained simulations were conducted with explicit sol- ...
11
QSAR modeling of estrogenic alkylphenols using bulk and electronic parameters
... be estrogenic and many techniques continue to be in implementation for defining pharmacophore signal for these, still little thorough structural evaluation has been presented in comparison to the endogenous ...
5
Fate and Biological Activity of Endocrine Disrupting Compounds in the Waste of a Commercial Swine Operation.
... Because all compounds in the lagoon carry an intrinsic risk of off-site transport following land application, it is important to understand the fate and occurrence of these EDCs within this widely used waste management ...
279
Effects of Environmental Contaminants and Natural Substances on Vitellogenesis in Tilapia Primary Hepatocytes
... from rainbow trout, O. mykiss, (Sumpter and Jobling 1995; Christiansen et al., 1998; Tremblay and Van Der Kraak 1998), Atlantic salmon, Salmo salar, (Celius et al., 1999; Arukwe et al., 2000; Tollefsen et al., 2003), ...
7