Anti-GBM disease
A case of aggressive atypical anti-GBM disease complicated by CMV pneumonitis
... linear GBM staining for IgG by IF, and negative anti-GBM serology fits previous descriptions of “atyp- ical” anti-GBM ...typical anti-GBM ...atypical ...
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Pulmonary renal syndrome in a child with coexistence of anti-neutrophil cytoplasmic antibodies and anti-glomerular basement membrane disease: case report and literature review
... renal disease was rela- tively mild consisting of microscopic hematuria and mild to moderate ...pANCA/anti-MPO anti- bodies indicated pauci-immune ANCA disease whereas intense linear IgG ...
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Anti-glomerular basement membrane disease: A case report of an uncommon presentation
... (anti-GBM) disease is an uncommon autoimmune disease that classically presents as an aggressive necrotizing and crescentic glomerulonephritis (CG), with or without pulmonary hemorrhage, and ...
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A 91-year-old woman with severe aortic stenosis successfully underwent maintenance hemodialysis via arteriovenous fistula after transcatheter aortic valve implantation: a case report with literature review
... serum anti-GBM antibody. Therefore, she was diagnosed with anti-GBM disease on ...of anti-GBM disease de- scribed in the English ...of anti-GBM ...
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Case Report Anti-GBM crescentic glomerulonephritis with intensive multinucleated giant cells: a case report
... Abstract: Anti-glomerular basement membrane (anti-GBM) disease is a rare but potentially lethal autoimmune dis- order with progressive renal dysfunction in a short time span, which is ...
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Deletion of PPAR-γ in immune cells enhances susceptibility to antiglomerular basement membrane disease
... given anti-GBM antibodies and inflammatory stimula- tion, these animals develop glomerular basement nephritis that in many ways resembles lupus nephritis and Goodpasture’s ...experimental ...
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The association of HLA-DQB1, -DQA1 and -DPB1 alleles with anti- glomerular basement membrane (GBM) disease in Chinese patients
... Among the 44 patients with anti-GBM disease, 30 were male and 14 were female. The median age of the 44 patients was 27 (range 13-82) years old on diagnosis. Six- teen out of 44 patients had pulmonary ...
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Comparison of double filtration plasmapheresis with immunoadsorption therapy in patients with anti-glomerular basement membrane nephritis
... with anti-glomerular basement membrane (anti-GBM) disease are ...with anti-GBM disease from 2003 to 2013 included 16 treated with DFPP and 12 with IA, with all patients ...
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Anti glomerular basement membrane glomerulonephritis following nintedanib for idiopathic pulmonary fibrosis: a case report
... with anti-GBM. This could be because anti-GBM disease is not only a rare disease but also the anti-GBM antibodies are intrinsically heterogeneous with respect to ...
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An Unusual Case of a Pulmonary Renal Syndrome with Negative Anti GBM and ANCA Antibodies
... and anti-GBM ...on anti-GBM and ANCA negative pulmonary-renal syndrome, an uncategorized subtype of this syndrome with unknown optimal ...
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Anti-hLAMP2-antibodies and dual positivity for anti-GBM and MPO-ANCA in a patient with relapsing pulmonary-renal syndrome
... for anti-hLAMP2 antibodies: First, Goodpasture’s syndrome is considered a non-relapsing disease ...the disease relapsed after a clinical and serological ...SVV-like disease: The initial biopsy ...
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Predicting Outcome in Patients with Anti-GBM Glomerulonephritis
... with anti-GBM GN and is therefore the largest study evaluating kidney biopsy samples in relation to clinical outcome in this rare ...this disease (9). Because of the rapid onset of ...
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A review on pulmonary renal syndromes
... circulating anti-neutrophil cytoplasmic antibody (ANCA) and anti-glomerular basement membrane (GBM) disease in children affected by this syndrome is exponential; with unfavorable out come in ...
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Antibody-Negative Relapse of Goodpasture Syndrome with Pulmonary Hemorrhage
... circulating anti-GBM antibodies detectable by enzyme- linked immunosorbent assay (ELISA) ...for anti- GBM antibodies is highly sensitive (>95%) and specific (>97%) ...human GBM. ...
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Bench to bedside review: Pulmonary–renal syndromes – an update for the intensivist
... underlying disease or may indicate the presence of primary pulmonary haemosiderosis, a result of indolent chronic or recurrent DAH ...veno-occlusive disease of the lung, mitral valve stenosis or cardiogenic ...
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Pharmacologic modulation of nasal epithelium augments neural stem cell targeting of glioblastoma
... effective anti-tumor therapies include difficulty in locating the precise tumor border for complete surgical resection, and rapid regrowth of residual tumor tissue after standard ...intranasal ...
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Preclinical Efficacy of Nimotuzumab, an Anti Egfr Monoclonal Antibody as a Single Agent Therapy in Human GBM u87mg Xenografts
... Background: The poor prognosis of patients with high-grade glioma multiform (GBM) has led investigators to the search of new therapeutic strategies. Current treatment includes surgery when possible, radiotherapy ...
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Original Article The selective mineralocorticoid receptor antagonist eplerenone is protective in mild anti-GBM glomeru- lonephritis
... of anti-GBM GN (reviewed by Tipping et ...the anti- inflammatory Th2 cytokine IL-10 was found to be increased in the lymph node as well as in restimulated splenocytes of Epl-treated ...an ...
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Kallikreins and lupus nephritis
... to anti-GBM antibody–induced nephritis and lupus ...to anti-GBM antibody–induced and lupus nephritis ...dampened anti-GBM antibody–induced nephritis, strongly suggesting a link ...
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PI3K/Akt/mTOR signaling pathway and targeted therapy for glioblastoma
... for GBM is radiation plus the chemopeutic agent temozolomide ...of GBM is frequently associated with molecular changes in epidermal growth factor receptor (EGFR) and phosphatidylinositol 3-kinase ...
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