Anti-HIV-1 effects
Interferon-Inducible CD169/Siglec1 Attenuates Anti-HIV-1 Effects of Alpha Interferon
... with HIV-1 Env- or MLV-A Env-pseudotyped lentivec- tors were not affected or were even enhanced in THP-1 ...and HIV-1 (reviewed in reference ...that HIV-1 infection can be ...
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Effects of Alpha Interferon Treatment on Intrinsic Anti-HIV-1 Immunity In Vivo
... of HIV-1 in ...of HIV-1 target cells may be important when evaluating cell-intrinsic immune ...␣ anti-HIV-1 effects should be explored in greater ...
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Anti-HIV-1 nanotherapeutics: promises and challenges for the future
... for HIV-infected patients has significantly improved; however, it has not eradicated HIV infection, particularly in sequestered, anatomically privileged sites, such as the brain, testes, gut, liver, kidney, ...
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Viral Diversity by Deep Sequencing: Approaches to Analyzing Effects of Anti-HIV Treatments
... of HIV-‐1 antisense therapy have used T cell populations in which the vast majority of viral target cells expressed the antisense ...defined HIV challenge ...model HIV-‐1 infection ...
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Inhibitory Effects of HIV-2 Vpx on Replication of HIV-1
... with 1% ...of HIV-2 CGP, ...in 1 ml lysis buffer (50 mM Tris-HCl, 250 mM NaCl, ...and HIV-2 Vpx monoclonal antibody (56), were used, followed by the use of secondary anti-mouse IgG ...
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Glycosyl-Phosphatidylinositol-Anchored Anti-HIV Env Single-Chain Variable Fragments Interfere with HIV-1 Env Processing and Viral Infectivity
... from HIV-1 ...for HIV-1 CCR5 (50) and CXCR4 (51, 52) via a number of RNA-based approaches such as ribozymes, short hairpin RNA (shRNA), and RNA inter- ference (RNAi) (53–55), or by introducing ...
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Effects of Cellular Activation on Anti-HIV-1 Restriction Factor Expression Profile in Primary Cells
... A summary of the mean fold changes (downregulation or up- regulation after stimulation) of all antiviral factors in the study population is shown in Fig. 1B. APOBEC3F and APOBEC3A were FIG 1 Host antiviral gene ...
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SYNTHESIS, ANTI VIRAL AND CYTOTOXICITY STUDIES OF SOME NOVEL N SUBSTITUTED BENZIMIDAZOLE DERIVATIVES
... Assay: Anti HIV Assay compounds were tested for their inhibitory effects against replication of HIV-1 (IIIB) and HIV-2 (ROD) in MT-4 cells 2 ...on HIV-1 and ...
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“(Cyclohexyl Methylene) Bis-Diacyl Phloroglucinol: An Inhibitor of HIV-1 Integrase In Vitro” by Sudeep Sabde, Debashis Mitra, Sanjay Toshniwal, India.
... of HIV-1 infection, leading to a dramatic reduction in AIDS-related morbidity and ...side effects, makes long-term compliance with drug regimens difficult for most ...the HIV-1 genome, ...
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Generation of Rhesus Macaque-Tropic HIV-1 Clones That Are Resistant to Major Anti-HIV-1 Restriction Factors
... of HIV-1mt clones to antagonize RhM tetherin may be very important for optimal replication and pathogenesis in RhM ...appreciable effects on viral replication in vitro is undetermined, the relationship ...
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A Screening strategy for selection of Anti-HIV-1 Integrase and anti-HIV-1 Protease Inhibitors from extracts of Indian Medicinal plants
... therapeutic effects, including antibacterial, antiviral, antifungal, antitumor, antihelminthetic, analgesic, hypotensive, anti- inflammatory and immune enhancing effects ...possess ...
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Dual role of α defensin 1 in anti–HIV 1 innate immunity
... on HIV-1 virions, although this inhibitory effect was lost in the presence of serum or an increase in virus particles (Figure ...postentry anti–HIV-1 activity of α-defen- sin-1 ...
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Characterization of the Outer Domain of the gp120 Glycoprotein from Human Immunodeficiency Virus Type 1
... the HIV-1 en- velope glycoproteins in the HIV-Ig and anti-HIV-1#1 and anti-HIV-1#2 sera, we measured the antibody titers specific for the outer domain ...
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Human Immunodeficiency Virus Type 1 Vpr Impairs Dendritic Cell Maturation and T-Cell Activation: Implications for Viral Immune Escape
... in HIV-1 immune ...by HIV-1 vpr ⫹ -infected DC following lipopolysaccharide (LPS) or CD40 ligand (CD40L) stimulation was also ...of HIV-1 vpr ⫹ virus-infected DC to impair ...
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Multicenter Evaluation of the New Automated Enzymun Test Anti HIV 1 + 2 + Subtyp O
... zymun-Test Anti-HIV 1 1 2 1 Subtyp O is suited very well for routine serologic diagnosis of HIV infection and screening of blood ...in anti-HIV-1 and ...
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Rapid Detection and Differentiation of Antibodies to HIV-1 and HIV-2 Using Multivalent Antigens and Magnetic Immunochromatography Testing
... rapid HIV antibody-screening assays has permit- ted the global expansion of HIV testing into rural, nonlabora- tory settings and has significantly increased the number of individuals that have been ...to ...
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Mechanisms of human immunodeficiency virus Type 1 (HIV-1) neutralization: irreversible inactivation of infectivity by anti-HIV-1 antibody.
... It remains to be determined what the importance of a neu- tralization assay conducted in the inactivation format de- scribed here will be. Most neutralization assays incorporate the important conditions emphasized here ...
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99005.2-20180920142741-covered-253bed37ca4c1ab43d105aefdf7b5536.pdf
... hu-mice. HIV-1 persists during effective cART in part because its genome becomes stably integrated into latently infected ...suppresses HIV-1 repli- cation in hu-mice, but cells harboring ...
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Evolution of subtype C HIV 1 Env in a slowly progressing Zambian infant
... A similar evaluation of the C2-V4 length polymorphism and PNGS alteration was carried out on subsequent infant samples to assess the longitudinal variation in these two parameters (Table 1 and Figure 4). Length ...
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Broad, Intense Anti-Human Immunodeficiency Virus (HIV) Ex Vivo CD8+ Responses in HIV Type 1-Infected Patients: Comparison with Anti-Epstein-Barr Virus Responses and Changes during Antiretroviral Therapy
... protein)-conjugated anti-CD8 and 15 l of phycoerythrin CPE)-conjugated anti-CD28 or with isotype-matched negative control ...of anti-human IFN-␥-fluorescein isothiocyanate (FITC) or with isotype- ...
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