anti-Hu
Neuronal uptake of anti-Hu antibody, but not anti-Ri antibody, leads to cell death in brain slice cultures
... of anti-Hu patient IgG and neuronal death before and after the antiserum had been adsorbed to recombinant HuD pro- ...used anti-Hu IgG which we had shown to produce extensive cell death in ...
15
Intrathecal synthesis of anti-Hu antibodies distinguishes patients with paraneoplastic peripheral neuropathy and encephalitis
... with anti-Hu ...with anti-Hu syndrome were regarded as one ...different anti-neuronal antibodies were summarized and/or regarded as one group [13, ...antineuronal anti- body ...
7
Raji cell assay for immune complexes Evidence for detection of Raji directed immunoglobulin G antibody in sera from patients with systemic lupus erythematosus
... goat anti-human Fc gamma, we found that digestion of Raji cells with pronase reduced by 95% their ability to bind complement-fixed aggregated human gamma globulin and complement-fixed tetanus toxoid-antitetanus ...
9
Entry inhibition of HSV 1 and 2 protects mice from viral lethal challenge
... Generation and production of an anti-HSV human mAb (Hu-mAb). The preparation of human antibody Fab libraries displayed on the surface of M13 phage has been described (Galanis et al., 2001). Briefly, ...
64
Mapping Antigenic Motifs in the Trypomastigote Small Surface Antigen from Trypanosoma cruzi
... Peptide chip synthesis and screening. The overall design, produc- tion, and screening of next-generation ultrahigh-density microarray slides (25) and the data analysis will be explained in detail elsewhere (S. J. ...
9
Pellkofer, Hannah (2005): Etablierung eines Tiermodells für paraneoplastische neurologische Erkrankungen. Dissertation, LMU München: Medizinische Fakultät
... Zytotoxizität anti-Hu positiver Seren ergab widersprüchliche ...Serum Hu+ Patienten toxisch auf Tumorzellen wirkt und sie in ihrem Wachstum hemmt (Verschuuren et ...Potential anti-Hu ...
155
Single Antigen Detects both Immunoglobulin M (IgM) and IgG Antibodies Elicited by All Four Dengue Virus Serotypes
... the anti-DEN virus IgG antibodies, followed by detection of the bound antibodies using the anti-human IgG–HRPO ...towards anti-DEN virus IgG antibodies of all four DEN virus ...corresponding ...
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Assessment of neuronal autoantibodies in patients with small cell lung cancer treated with chemotherapy with or without ipilimumab
... of anti-Hu 28 . Around 1% of positivity of anti-HuD was reported in patients diagnosed of PNS 28,29 ...for anti-Hu, but when testing also for other NAAs (Sox2, HuD, Gad65, Amphyphisin, ...
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High-Avidity Monoclonal Antibodies against the Human Scavenger Class B Type I Receptor Efficiently Block Hepatitis C Virus Infection in the Presence of High-Density Lipoprotein
... 6. Anti-SR-B1 MAbs inhibit infection of ...of anti-SR-B1 antibody (MAb C167; gray bars), anti-human-CD81 (MAb ...of anti-SR-B1 MAb C167 (indicated on the horizontal axis on a logarithmic ...
9
Clinical Reasoning: A 35-year-old woman with acute seizures and behavior change
... example, anti-Hu antibody limbic encephalitis is more frequently seen in small-cell lung cancers, anti-Ma antibody with testis or lung cancers, and amphiphysin antibody with breast and small-cell ...
6
Functional Evolution of Bacterial Histone-Like HU Proteins
... different HU orthologs may be reflected in different DNA site sizes in duplex ...Anabaena HU structure (in this structure, the arginine makes crystal packing contacts to a neighboring complex (Rice et ...
12
Glycosylphosphatidylinositol-Anchored Anti-HIV scFv Efficiently Protects CD4 T Cells from HIV-1 Infection and Deletion in hu-PBL Mice
... A limitation of the present study is that the prolonged therapeutic impact of GPI-scFv X5 has not been addressed. In this proof-of-concept study, we have shown vigorous protection by GPI-scFv X5 in a humanized mouse ...
19
Transplanted human fecal microbiota enhanced Guillain Barré syndrome autoantibody responses after Campylobacter jejuni infection in C57BL/6 mice
... C. jejuni is a leading cause of bacterial diarrheal illness and the leading antecedent infection to the autoimmune acute peripheral neuropathy GBS [21, 34]. In previous work, we developed mouse models of both enteric and ...
22
Present Situation and Prospective of Camellia Nut Shells Utilization
... drolyzed tannins and condensed tannins and can be found in most plants. Camellia nut shells are an abundant natural tannin source due to its high tannin content. Solvents with a good solubility for tannin and ability to ...
9
Original Article Losartan alleviates hyperuricemia-induced atherosclerosis in a rabbit model
... alleviate HU-induced experimental AS by downregulating angiotensin II ...that HU alone could significantly increase plasma renin/angi- otensin activity in a way similar to HC with com- plicating HU, ...
8
Original Article Cellular microRNA-214 contributes to H1N1 influenza A virus-mediated apoptosis through repression of anti-apoptotic factors Livin in A549 cells
... ment, cancer, viral pathogenesis and so on [11- 13]. Increasing evidence supports that microR- NAs have important functions in viral replica- tion and may be used by host cells to inhibit or promote viral infections. ...
8
Dissecting the donor star in the eclipsing polar HU Aquarii
... Fig. 4. Observed and predicted radial velocity amplitudes of the sec- ondary star in HU Aqr. Blue lines from bottom left to upper right in- dicate model data for the irradiated and non-irradiated hemispheres of ...
7
Testing times: trends in availability, price, and market share of malaria diagnostics in the public and private healthcare sector across eight sub Saharan African countries from 2009 to 2015
... reasons for carrying out the test, particularly among RDT-negative patients [38]. There are also inherent chal- lenges when patients test negative for malaria, particu- larly in the private sector, where providers may ...
16
Novel targeting of PEGylated liposomes for codelivery of TGF-β1 siRNA and four antitubercular drugs to human macrophages for the treatment of mycobacterial infection: a quantitative proteomic study
... Given the physicochemical properties of the novel NP- siRNA liposomes, the results have demonstrated that the liposomes can be used to encapsulate the anti-TB drugs. The novel NP-siRNA liposomes are facile to be ...
30
Antagonism of TIM 1 blocks the development of disease in a humanized mouse model of allergic asthma
... liferation and IL-5 production after coculture with D. pteronyssinus plus autologous myeloid DCs from nonallergic control and asthmatic donors. In vivo experiments (A–D and J) included nonallergic donor controls and ...
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