Anti-thymocyte globulin
Low-dose post-transplant cyclophosphamide and anti-thymocyte globulin as an effective strategy for GVHD prevention in haploidentical patients
... During the past 20 years, wider application of easily available haploidentical donor hematopoietic cell trans- plant (haplo-HCT) has been made possible through the T cell-replete (TCR) regimens including T cell regula- ...
9
Equine Anti-Thymocyte Globulin (ATGAM) administration in patient with previous rabbit Anti-Thymocyte Globulin (Thymoglobulin) induced serum sickness: A case report
... ATGAM is an anti-thymocyte globulin that differs from thymoglobulin by being produced in horses rather than rabbits. Typically, thymoglobulin is preferred over ATGAM in the U.S. as thymoglobulin has ...
5
The Anti-thymocyte Globulin use makes kidney transplantation journey smooth
... rabbit anti-thymocyte globulin (rATG) especially in the population who received a simultaneous kidney and pancreas transplant, failed to draw major conclusions due to improper study designs and ...
11
Induction of procalcitonin in liver transplant patients treated with anti thymocyte globulin
... the anti-thymocyte globulin (ATG) (9 mg/kg) (Fresenius, Fresenius Biotech GmbH, Gräfelfing, Germany) and methylprednisolone 250 mg during the anhepatic ...
5
Rabbit anti-thymocyte globulin induction in renal transplantation: review of the literature
... nondepleting anti- bodies (Table ...rabbit anti-thymocyte globulin (rATG), equine anti-thymocyte globulin (eATG), monomurab-CD3 (OKT3), and alemtuzumab, are generally ...
13
Marked increase of procalcitonin after the administration of anti thymocyte globulin in patients before hematopoietic stem cell transplantation does not indicate sepsis: a prospective study
... Anti-thymocyte globulin (ATG) is frequently used as part of a conditioning regimen in patients scheduled for allogeneic hematopoietic stem cell ...
7
Anti thymocyte globulin/G CSF treatment preserves β cell function in patients with established type 1 diabetes
... harvest, anti-thymocyte globulin (ATG), stem cell infusion, granulocyte CSF (G-CSF), and intensive inpatient and outpatient support, this approach demonstrated the capacity to achieve short-term ...
9
Relationship between post-transplant lymphoproliferative disorder and Anti-Thymocyte Globulin or Anti-Lymphocyte Globulin
... Background: Lymphoproliferative disorders are among the most serious and potentially fatal complications of chronic immunosuppression in kidney trans- plant recipients. The principle risk factors for development of PTLD ...
7
Unmanipulated haploidentical stem cell transplantation in adults with acute lymphoblastic leukemia: a study on behalf of the Acute Leukemia Working Party of the EBMT
... Background: Allogenic hematopoietic stem cell transplantation (allo-SCT) is the most effective post-remission treatment for adults with high-risk acute lymphoblastic leukemia (ALL). The aim of the study was to analyze ...
11
Comparison of Induction Therapy Using Antithymocyte Globulin and Using Basiliximab for Live Donor Kidney Transplant Recipients: A Single Centre Prospective Cohort Study
... Renal transplantation is the treatment of choice for patients with end- stage renal disease, to improve both qualities of life and life expectancy. Controlling the alloimmune reaction is imperative for successful renal ...
5
Allogeneic stem cell transplantation in adult patients with acute myeloid leukaemia and 17p abnormalities in first complete remission: a study from the Acute Leukemia Working Party (ALWP) of the European Society for Blood and Marrow Transplantation (EBMT)
... ATG: Anti-thymocyte globulin; CB: Cord blood; CI: Confidence interval; CK: Complex caryotype; CMV: Cytomegalovirus; CR1: First complete remission; CR2: Second complete remission; DLI: Donor leukocyte ...
10
<p>Cardiac toxicity of immune-checkpoint inhibitors: a clinical case of nivolumab-induced myocarditis and review of the evidence and new challenges</p>
... used. Anti-thymocyte globulin (ATG) has been classically used in the prophylaxis of graft versus host disease due to its ability to deplete T lymphocytes, among ...an anti-TNF drug, has also ...
8
Who is the best haploidentical donor for acquired severe aplastic anemia? Experience from a multicenter study
... aGVHD: Acute graft-versus-host disease; allo-HSCT: Allogeneic hematopoietic stem cell transplantation; ATG: Anti-thymocyte globulin; BM: Bone marrow; BU: Busulfan; cGVHD: Chronic graft-v[r] ...
11
Impact of in vivo T cell depletion in HLA-identical allogeneic stem cell transplantation for acute myeloid leukemia in first complete remission conditioned with a fludarabine iv-busulfan myeloablative regimen: a report from the EBMT Acute Leukemia Working Party
... with anti-thymocyte globulin (ATG) reduces the incidence of cGVHD without increasing the risk of re- lapse in allo-SCT performed with PBSC from MRD or MUD after conventional cyclophosphamide-based ...
11
Recent advances in the diagnosis and treatment of hemophagocytic lymphohistiocytosis
... APCs. Anti-thymocyte globulin (ATG) directly targets T cells, whereas alemtu- zu mab, an anti-CD52 antibody, targets lymphocytes in general and ...
12
Haploidentical transplantation is associated with better overall survival when compared to single cord blood transplantation: an EBMT-Eurocord study of acute leukemia patients conditioned with thiotepa, busulfan, and fludarabine
... Patient and disease characteristics are summarized in Table 1. Per protocol, all patients received a TBF-MAC-based regimen. The two populations were overall homogeneous in terms of patients and disease characteristics, ...
10
Investigating remission and relapse in type 1 diabetes. Immune correlates of clinical outcome in beta-cell replacement therapies
... of anti-thymocyte globulin (ATG) induction and maintenance therapy with mycophenolate mofetil (MMF) and calcineurin inhibitors (CNI; n=28) or sirolimus with (n=3) or without (n=4) ...
90
Haploidentical allograft is superior to matched sibling donor allograft in eradicating pre-transplantation minimal residual disease of AML patients as determined by multiparameter flow cytometry: a retrospective and prospective analysis
... with anti-thymocyte globulin (ATG) [3, 9, 10] or with post- cyclophosphamide (PT/Cy) [3], is widely accepted as a viable alternative for patients without HLA-identical donors, and its outcomes may be ...
13
Autologous hematopoietic cell transplantation in multiple sclerosis.
... Abbreviations rATG Rabbit Anti-Thymocyte Globulin AHCT Autologous Hematopoietic Cell Transplantation BEAM BCNU, Ara-C, etoposide and melphalan BuCy Busulfan, cyclophosphamide, and rabbit[r] ...
37
Single- or double-unit UCBT following RIC in adults with AL: a report from Eurocord, the ALWP and the CTIWP of the EBMT
... ATG: Anti- thymocyte globulin; CB: Umbilical cord blood; CBT: Umbilical cord blood transplantation; CI: Confidence interval; CR: Complete remission; dCBT: Double- unit cord blood transplantation; ...
11