Anti-TNF therapy
Effect of Anti TNF Therapy on Resistance to Insulin in Patients with Rheumatoid Arthritis
... of anti-hypertensive drugs, triglycerides > 150 mg/dl, hypercho- lesterolemia > 200 mg/dl, high-density lipoproteins < 40 mg/dl in men and < 50 mg/in women, or with lipids lowering agents, waist ...
5
Gastric Neoplasia during Anti TNF Therapy for Crohn’s Disease: Casual Event?
... Biological therapy is a major advancement in the treatment of ...prolonged anti-TNF therapy arises concern about their adverse events in ...to anti-TNF therapy, at a ...
5
Blood-based identification of non-responders to anti-TNF therapy in rheumatoid arthritis
... of anti-TNF non- responders may generally have lower cytokine signaling involved in inflammation, including TNF and NF-κB path- ways, while having higher levels of specific metabolic activities ...
12
Clinical use of anti-TNF therapy and increased risk of infections
... on anti-TNF therapy, and physicians who utilize these agents must understand the increased risks of ...with anti-TNF therapy was performed and the clinical presentation, ...
21
Original Article The potential of TNF and TNFRSF1B gene polymorphism in predicting the clinical response of anti-TNF therapy in patients with juvenile idiopathic arthritis
... of anti-TNF therapy in JIA ...received anti-TNF treatment for 24 ...(rs1800629), TNF- 238 (rs361525), TNFRSF1B (rs1061622), TRAF1/C5 (rs3761847), and PTPN22 (rs2488457)) by PCR ...
8
Large Vessel Vasculitis Occurring in Rheumatoid Arthritis Patient under Anti-TNF Therapy
... anticoagulant therapy was ...The anti-TNF therapy was stopped and glucocorticoid therapy was started at doses of 1 mg/kg/daily in association with one dose of intravenous pulse ...
6
Improvement in symptoms and signs in the forefoot of patients with rheumatoid arthritis treated with anti-TNF therapy
... Foot symptoms were not inclusion criteria within our study, yet the high prevalence detectable by US was sur- prising. There are suggestions that clinically evident dis- ease improves more quickly following effective ...
9
Cronkhite-Canada Syndrome: Sustained Clinical Response with Anti-TNF Therapy
... Copyright © 2018 S. A. Taylor et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...
6
TWEAK binding autoantibodies are generated during psoriatic arthritis and are not influenced by anti TNF therapy
... the TNF ligand superfamily that can be cleaved to function as a soluble cytokine ...context, anti-TNF therapy has been suc- cessful in PsoA concordant with the key pro-inflamma- tory role of ...
10
The immunogenicity to the first anti TNF therapy determines the outcome of switching to a second anti TNF therapy in spondyloarthritis patients
... first anti-TNF drug have been reported in the literature, including shorter disease duration, younger age, HLA-B27 positivity, a lower Bath Ankylos- ing Spondylitis Functional Index score, higher C-reactive ...
7
TNFR1 Deficiency Protects Mice from Colitis Associated Colorectal Cancer Coupled with a Decreased Level of Oxidative Damage in the Colon: Implications for Anti TNF Therapy of Unremitting Colitis
... pathways, TNF can contribute to oxidative stress by inducing the production of reactive oxygen spe- cies (ROS) via several isoforms of NADPH oxidase ...[21,22]. TNF treatment can directly lead to oxidative ...
15
Rituximab is more effective than second anti-TNF therapy in rheumatoid arthritis patients and previous TNFα blocker failure
... retrospectively from two cohorts that were treated either with rituximab or a second TNF α blocker. Treatments were not randomized and no information was available as to why patients were treated with either ...
9
Anti-TNF therapy in Jordan: a focus on severe infections and tuberculosis
... standard deviations of age in years at initiation of anti-TNF and duration of treatment with an anti-TNF were computed. Frequencies and percentages were used to describe categori- cal patient ...
6
Anti-TNF therapy for juvenile idiopathic arthritis-related uveitis
... uveitis. Anti-TNF agents have revolutionized the treatment of JIA, as they achieve better control of the disease than previously possible with all other disease-modifying anti-rheumatic ...ventional ...
8
“Serious skin & soft tissue infections in rheumatoid arthritis patients taking anti tumor necrosis factor alpha drugs: a nested case–control study”
... between anti- TNF drug treatment and an increase in all serious infec- tions in RA patients ...between anti-TNF therapy and increased risk of infection in RA patients ...receiving ...
7
Factors associated with ASDAS remission in a long-term study of ankylosing spondylitis patients under tumor necrosis factor inhibitors
... Patients were evaluated using an electronic chart database protocol established in 2000 with periodical assessment of parameters of treatment response and adverse events. Acute phase reactants, as CRP and Erythrocyte ...
8
Reduction of autophagy and increase in apoptosis correlates with a favorable clinical outcome in patients with rheumatoid arthritis treated with anti TNF drugs
... a result, the amount of LC3-II (at baseline and after anti-TNF therapy) directly correlated with disease ac- tivity score, showing that levels of autophagy may be a measure of disease progression. ...
11
Potential Vaccines for Treating Crohn's Disease
... of TNF-α in inflammatory response, targeting this pro-inflammatory cytokine would be associated with great advantages for any type of inflammatory ...against TNF-α, as a potential target, is a novel ...
14
Unexpected arterial wall and cellular inflammation in patients with rheumatoid arthritis in remission using biological therapy: a cross sectional study
... As TNF inhibitors were previously shown to effectively lower arterial wall inflammation [15], our findings are most likely explained by inherent differences between treatment ...without anti-TNF ...
9
Biologics and cardiovascular events in inflammatory arthritis: a prospective national cohort study
... with anti-TNF agents compared with conventional DMARDs was also reported in a recently updated analysis of the British So- ciety for Rheumatology Biologic Register (BSRBR-RA) ...using anti-TNF ...
9