Anti- tumor activity
Evaluation of anti-tumor activity of Momordica cymbalaria fenzl
... of anti-tumor activity against mammary cancer, which may be due to its anti-estrogenic, hormonal level is decreasing by the estrogen level and by increasing the LH, FSH level in DMBA control ...
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Synthesis of benzothiazole selenato complexes and determination of its anti-tumor activity
... INTRODUCTION In last few years there has been considerable interest in the synthesis and characterization of metal complexes of ligands derived from heterocyclic molecule because of their biological significance 1 . The ...
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DNA-demethylating and anti-tumor activity of synthetic miR- 29b mimics in multiple myeloma
... and anti-tumor activity of synthetic miR- 29b mimics in multiple myeloma Nicola Amodio 1 , Marzia Leotta 1 , Dina Bellizzi 2 , Maria Teresa Di Martino 1 , Patrizia D’Aquila 2 , Marta Lionetti 3 , ...
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In Vitro and in Vivo Anti-tumor Activity of miR-221/222 Inhibitors in Multiple Myeloma
... of anti-tumor activity of miR-221/222 inhibitors against MM ...successful tumor-uptake of miRNA inhibitors at concentrations sufficient to produce up- regulation of target mRNAs and proteins ...
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Isolation of alkaloids and anti-tumor activity of the crude methanolic extract of Algerian Cytisus purgans
... The anti-tumor activity of the crude methanolic extract of the aerial parts of the plant was also evaluated invitro against human breast cancer (MDA-MB-231) and human lung cancer (A549) cell lines ...
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Anti-tumor activity of N-trimethyl chitosan-encapsulated camptothecin in a mouse melanoma model
... The anti-tumor activity of CPT-TMC was evaluated in C57BL/6 mice bearing B16- F10 ...melanoma. Tumor volume, tumor weight and survival time were ...within tumor tissue was ...
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Anti tumor activity and toxicokinetics analysis of MGAH22, an anti HER2 monoclonal antibody with enhanced Fcγ receptor binding properties
... IgG1 anti-HER2 antibody based on mouse clone 4D5, the precursor to ...direct anti-proliferative activity of trastuzumab against sensitive cell lines, these enhanced binding prop- erties confer ...
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Evaluation of antimicrobial activity, Minimum Inhibitory Concentration (MIC) & Anti tumor activity of Elettariacardamomum and Ferula assa foetida leaves
... aspect of antitumor studies. After 2 weeks incubation of A. tumefacienson each carrot disc in this research, negative control which use only for pathogenicity test showed young galls (tumors) developing from the ...
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ANTI TUMOR ACTIVITY AND ANTI OXIDANT STATUS OF EUPHORBIA THYMIFOLIA LINN AGAINST EHRLICH ASCITES CARCINOMA IN SWISS ALBINO MICE
... study Anti-tumor effect and anti-oxidant status of Euphorbia thymifolia Linn Materials & Methods: The present study deals with life span of Ehrlich ascites carcinoma bearing hosts, peritoneal cell ...
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Rottlerin exerts its anti-tumor activity through inhibition of Skp2 in breast cancer cells
... Received: June 06, 2016 Accepted: August 15, 2016 Published: August 25, 2016 ABSTRACT Studies have investigated the tumor suppressive role of rottlerin in carcinogenesis. However, the molecular mechanisms of ...
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Nanosuspension delivery of paclitaxel to xenograft mice can alter drug disposition and anti tumor activity
... and anti-tumor efficacy for paclitaxel delivered using a standard com- mercial formulation and a ...paclitaxel's anti- tumor ...xenograft tumor-bearing mice when delivered with the ...
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Characterization and anti-tumor activity of a polysaccharide isolated from Dendrobium officinale grown in the Huoshan County
... polysaccharide activity varies depending on its structure ...for anti-tumor activity ...high anti-tumor activity and that their main glucan linkages are β-(1 → 6) and β-(1 ...
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B cell depletion or absence does not impede anti-tumor activity of PD-1 inhibitors
... As immune checkpoint inhibitors are becoming widely used in multiple tumor types, they are also being used in B cell malignancies. Many patients with B cell malignan- cies have received B cell eliminating drugs, ...
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Optimization of the fermentation process of Cordyceps sobolifera Se-CEPS and its anti-tumor activity in vivo
... having anti-aging and anti-fatigue activ- ities [4], having anti-tumor activity [4], improving renal function [5–8], and providing nourishment and strength ...
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Enhancing Anti-Tumor Activity of Checkpoint Inhibition
... Each dot represents lysis of a different human tumor cell line. A, Correlation between % PD-L1 positive tumor cells and % ADCC lysis (p<0.0001, r=0.799). B, Correlation between PD-L1 tumor cell ...
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Synthesis and Anti-Tumor Activity of Oleanolic Acid Derivatives
... Abstract Using the techniques of computer-aided drug design, the docking of Survivin and known active small molecules was simulated and then the key amino acid residue fragment of the target protein was analyzed. It led ...
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Synthesis and Anti-Tumor Activity of Oleanolic Acid Derivatives
... Abstract: With the computer drug-aided design and the key amino acid residue fragment of the target protein analyzed on the basis of simulated docking of Survivin and known active small molecules, the active groups ...
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ANTI TUMOR ACTIVITY OF FRUIT EXTRACTS OF MOMORDICA DIOICA ROXB
... antitumor activity of extracts of MDR against DLA induced solid tumor ...Solid tumor DLA cells were aspirated from the peritoneal cavity of DLA bearing mouse, after 15 days of tumor ...
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L-Cycloserine Amplifies Anti-Tumor Activity of Glutamine Antagonist
... analysis of the tumor tissue, performed 24 h after these treatments in order to confirm their influences on amino acid metabolism in the tumor, showed that the in[r] ...
Synthesis of acyl oleanolic acid-uracil conjugates and their anti-tumor activity
... structed in many new compounds in various anti‑tumor studies. Results: Five acyl oleanolic acid‑uracil conjugates were synthesized. Most of the IC 50 values of these conjugates were lower than 10.0 μM, and ...
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