Antiarrhythmic Drugs
Renal sympathetic denervation versus antiarrhythmic drugs for drug resistant hypertension and symptomatic atrial fibrillation (RSDforAF) trial: study protocol for a randomized controlled trial
... substantially reduce blood pressure, left ventricular hyper- trophy and sleep apnea severity, and improve glucose tol- erance. Simultaneously, a marked reduction in muscle and whole-body sympathetic nerve activity is ...
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Antiarrhythmic drugs for out of hospital cardiac arrest with refractory ventricular fibrillation
... between antiarrhythmic drug administration and defibrillation success in the amiodarone group was significantly longer than that in the nifekalant group ...of antiarrhythmic drugs (defined as any one ...
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European Resuscitation Council Guidelines for Resuscitation : 2018 Update – antiarrhythmic drugs for cardiac arrest
... The recommendations of the ERC are unchanged for the use of antiarrhythmic drugs in infants and children. 9 For VF/pVT give amiodarone 5 mg kg −1 after the third shock once CPR has been resumed. Give a ...
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Hertrich, Ursula (2003): Auswirkungen der invasiv ausgestesteten medikamentösen antiarrhythmischen Therapie auf die Prognose von Patienten mit ventrikulären Tachyarrhythmien: Antiarrhythmic Drugs Improve Outcome Study (ADIOS). Dissertation, LMU München: Medizinische Fakultät
... Von den 29 Patienten, die mit dem als effektiv getesteten Medikament behandelt wurden, erlitten 6 Patienten (21 %) ein Arrhythmierezidiv oder verstarben an plötzlichem Her[r] ...
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Effectiveness of antiarrhythmic drugs for shockable cardiac arrest : a systematic review
... anti-arrhythmic drugs showed any difference in effect compared with placebo, or with other anti-arrhythmic drugs for the critical outcomes of survival to hospital discharge and discharge with good ...
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Blockade of cardiac sodium channels Competition between the permeant ion and antiarrhythmic drugs
... increase in [Na]o. This increase in single-channel current amplitude would affect drug-free channels only, in that our studies suggest that drug-associated channels do not conduct. The association rate constant of ...
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Arrhythmic burden and outcomes in pulmonary arterial hypertension
... Pulmonary arterial hypertension (PAH) is a devastating, life-limiting disease driven by small vessel vascular remodeling leading to a rise in pulmonary vascular resistance (PVR). Patients present with a range of symptoms ...
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Severe iatrogenic bradycardia related to the combined use of beta-blocking agents and sodium channel blockers
... have had asymptomatic bradycardia that would have been identified during 24-hour ECG monitoring. Although they might have been predisposed to latent sinus node dysfunction, their sinus rates were within normal limits ...
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Is amiodarone a safe antiarrhythmic to use in supraventricular tachyarrhythmias after lung cancer surgery?
... III antiarrhythmic drugs, ibutilide has been used currently with moderate success to convert acute atrial fibrillation in 57% of patients after cardiac surgery, however polymorhic ven- tricular tachycardia ...
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Avoiding permanent atrial fibrillation: treatment approaches to prevent disease progression
... of antiarrhythmic drugs and avoiding repeated cardioversions. Drugs used for rate control include beta-adrenergic blockers, nondihydropyri- dine calcium channel antagonists, and ...
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Resetting of Cardiac Ventricular Tachycardia Storm with Intravenous Potassium Chloride: A Case Report
... Ventricular Tachycardia Storm (VTS) with hemodynamic instability is a life- threatening arrhythmia more often presents in patients with structural heart disease. Lack of response to cardioversion and/or ...
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Upregulation of the rat cardiac sodium channel by in vivo treatment with a class I antiarrhythmic drug
... I antiarrhythmic drugs inhibit the sodium channel by binding to a drug receptor associated with the ...I antiarrhythmic drug mexiletine to rats induces sodium channel upregulation in isolated cardiac ...
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Dronedarone: evidence supporting its therapeutic use in the treatment of atrial fibrillation
... Several important issues regarding the use of dronedarone emerged from this study. Oral administration of dronedarone 400 mg twice daily could safely maintain sinus rhythm in patients with previous atrial fibrillation ...
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The cardioprotective and antiarrhythmic effects of Nardostachys chinensis in animal and cell experiments
... western antiarrhythmic drugs are associated with notable adverse effects, and certain agents may even be proarrhythmic [7] as confirmed by the Cardiac Arrhythmia Suppression Trial (CAST) ...
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Antiarrhythmic properties of atrial pacing
... drug-refractory paroxysmal or persistent atrial fibrilla- tion and a sinus P-wave duration ≥ 120 ms, this treatment resulted in a decrease of the incidence and duration of AF-related hospitalizations, lowering the mean ...
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Pharmacologic Basis for the Treatment of Cardiac Arrhythmias
... cells, antiarrhythmic drugs further modify cardiac. electrical events through their action on the auto-[r] ...
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Left atrium remodeling predicts late recurrence of paroxysmal atrial fibrillation after second generation cryoballoon ablation
... AADs: Antiarrhythmic drugs; AF: Atrial fibrillation; BP: Blanking period; CBA: Cryoballoon ablation; ECG: Electrocardiogram; ICC: Intraclass correlation coefficient; ILMC: Inner lumen mapping catheter; LA: ...
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Reversal of lidocaine effects on sodium currents by isoproterenol in rabbit hearts and heart cells
... We demonstrated recently that isoproterenol enhanced the cardiac voltage-dependent sodium currents (INa) in rabbit ventricular myocytes through dual G-protein regulatory pathways. In this study, we tested the hypothesis ...
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UK 68,798, A Class III Antiarrhythmic Drug with Antifibrillatory Properties
... The antifibrillatory effect of UK-68,798 in the conscious canine model of sudden cardiac death is in accord with results obtained with other class 111 antiarrhythmic drugs such as CK3579[r] ...
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Safety and efficacy of vernakalant for acute cardioversion of atrial fibrillation: an update
... The conventional class IC (flecainide, propafenone) and class III (amiodarone and ibutilide) antiarrhythmic drugs that are commonly used for the acute termination of recent[r] ...
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