Antibody-mediated rejection (ABMR)
Clazakizumab in late antibody mediated rejection: study protocol of a randomized controlled pilot trial
... Late antibody-mediated rejection (ABMR) triggered by donor-specific antibodies (DSA) is a cardinal cause of kidney allograft dysfunction and ...this rejection type are well established, ...
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Eculizumab to Treat Antibody-Mediated Rejection in a 7-Year-Old Kidney Transplant Recipient
... acute antibody-mediated rejection (ABMR) in a highly sensitized kidney transplant ...severe ABMR in pediatric transplantation, and therefore it suggests a novel therapeutic approach to ...
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Eculizumab to Treat Antibody-Mediated Rejection in a 7-Year-Old Kidney Transplant Recipient
... acute antibody-mediated rejection (ABMR) in a highly sensitized kidney transplant ...severe ABMR in pediatric transplantation, and therefore it suggests a novel therapeutic approach to ...
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Original Article Acute cellular rejection and antibody-mediated rejection in endomyocardial biopsy after heart transplantation: a retrospective study from a single medical center
... Allograft Rejection [7] and the ISHLT 2013 Working Formulation for the standardization of nomenclature in the pathologic diagnosis of antibody-mediated rejection in heart transplan- tation ...
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Current perspectives on antibody-mediated rejection after lung transplantation
... proposed by the ISHLT Pathology Council and the National Conference to Assess Antibody-Mediated Rejection in Solid Organ Transplantation. We defined acute AMR as: allograft dysfunction; circulating ...
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Treatment of acute antibody-mediated rejection using Rituximab
... Acute rejection (AR) is one of its complications that are associated with a high frequency of graft loss in some cases or graft dysfunction in others (1, ...Acute Antibody Mediated Rejection ...
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Rituximab, plasma exchange and immunoglobulins: an ineffective treatment for chronic active antibody-mediated rejection
... active antibody-mediated rejection; CCI: Charlson comorbidity index; DSA: Donor specific antibodies; eGFR: Estimated glomerular filtrated rate; IFTA: Interstitial fibrosis and tubular atrophy; IVIG: ...
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Treatment with intravenous immunoglobulins and methylprednisolone may significantly decrease loss of renal function in chronic-active antibody-mediated rejection
... Chronic-active Antibody Mediated Rejection (c-aABMR) is an important cause of renal allograft dysfunction over time, often presenting as a continuous decline in allograft function, either with or ...
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Antibody mediated rejection across solid organ transplants: manifestations, mechanisms, and therapies
... of antibody-mediated rejection (AMR), and our knowledge of the mechanisms of antibody-medi- ated allograft injury have expanded our understanding of ...
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Endothelial chimerism and vascular sequestration protect pancreatic islet grafts from antibody mediated rejection
... We believe that our study also has more general implications in immunology. Our data indeed indicate that the reduced con- centrations of several key components of the humoral response in interstitial tissue make it ...
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Late antibody-mediated rejection after ABO-incompatible kidney transplantation during Gram-negative sepsis
... details). Antibody titer changes were investigated as well: after centrifugation the supernatant was stored at 4°C and anti-A titers were measured the following day by adding A erythrocytes in serial plasma ...
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The Effect of Bortezomib on Antibody Mediated Rejection after Kidney Transplantation
... Treatment outcomes are shown in Table 3 and Fig. 1. Six epi- sodes of AMR occurred within 6 months of transplantation. Patient B (refer to Table 3 for patient details) had anti-B anti- body and class II HLA ...
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Myocardial T1 mapping: where are we now and where are we going?
... Cardiac magnetic resonance T1 mapping pre and post contrast in heart transplant patients with clinical antibody-mediated rejection: a preliminary experience. Edwards NC, Moody W[r] ...
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Rituximab: An emerging therapeutic agent for kidney transplantation
... and antibody responses in solid-organ transplant ...of antibody-mediated rejection (AMR), post-transplant lymphoproliferative disorder (PTLD), and recurrent glomerular diseases in the renal ...
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Bortezomib in late antibody mediated kidney transplant rejection (BORTEJECT Study): study protocol for a randomized controlled trial
... Background: Despite major advances in transplant medicine, improvements in long-term kidney allograft survival have not been commensurate with those observed shortly after transplantation. The formation of donor-specific ...
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Delayed hyperacute rejection in a patient who developed <em>clostridium difficile</em> infection after ABO-incompatible kidney transplantation
... group antibody titers (anti-A/B) before transplantation and a rebound antibody production after antibody removal may be at high immunological ...anti-A/B antibody titers before plasmapheresis ...
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Bronchus associated lymphoid tissue–resident Foxp3+ T lymphocytes prevent antibody mediated lung rejection
... Antibody-mediated rejection (AMR) is a principal cause of acute and chronic failure of lung ...in rejection-free human lung grafts and accumulated within induced bronchus-associated lymphoid ...
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Expression of MMP-2 and TIMP-1 in Renal Tissue of Patients with Chronic Active Antibody-mediated Renal Graft Rejection
... humoral rejection and was included in Banff 07 pathologic diagnostic criteria, there- fore chronic active antibody-mediated rejection (AMR) was being paid more and more attention ...
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Immunosuppressive therapy with rituximab in common variable immunodeficiency
... severe antibody deficiency in adulthood and is character- ized by the reduction of serum immunoglobulin levels (namely IgG and IgA) and the impairment of antibody production in response to pathogens and ...
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B cells mediate chronic allograft rejection independently of antibody production
... acute rejection was inhibited by treating recipients with costimu- lation blockade (CTLA4Ig and anti-CD40L) ...and antibody sufficient B6 (WT) mice were used as ...
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