anticoagulant activity
Platelet factor 4 impairs the anticoagulant activity of activated protein C
... APC anticoagulant activ- ity in plasma constitutes the most common laboratory abnor- mality identified in patients with venous ...APC anticoagulant activity is caused by the FV Leiden polymorphism ...
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Anticoagulant Activity of Substituted Hydroxy Propoxycoumarin Derivatives
... to study pharmacological screening and synthetic aspects of the coumarin ring structure especially its combined analogues profile as an anticoagulant and antihypertensive property. Our first aim is to study ...
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Evaluation of anticoagulant activity of aqueous extract of Cestrum nocturnum
... for 5 min. Then, 200 μL of PT assay reagent (rabbit brain extract and calcium chloride) pre-warmed at 37°C for 10 min was added and the clotting time was recorded by a digital coagulometer(Model No-ABC2202 “Bioline ...
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A novel anticoagulant activity assay of tissue factor pathway inhibitor I (TFPI)
... catalytic activity with similar efficiency irrespective of the nature of the TFPI, ...n-TFPIac activity, clotting occurs within approximately 75 s after the addition of a small amount of TF, and reaction ...
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The Anticoagulant Activity of Lysosomal Cationic Proteins from Polymorphonuclear Leukocytes
... anticoagulant activity is detectable in the whole blood clotting time, the recalcification time of platelet-rich plasma, the prothrombin time, the partial thromboplastin time, and the thromboplastin ...
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ANTICOAGULANT ACTIVITY OF ETHANOL AND AQUEOUS EXTRACTS OF PETROSELINUM CRISPUM MILL.
... the Anticoagulant activity of Petroselinum crispum ...whose anticoagulant effectiveness is comparable to that of its commercial counterpart, warfarin, (Group III) showed a positive inhibition of clot ...
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Preparation and characterization of polysaccharide-based nanoparticles with anticoagulant activity
... The particle analysis performed on NP1 after sequen- tial centrifugation revealed particles presenting MD of 3545.8 nm (.5.0% of total mass) for NP1 at the first step. The supernatant was sequentially centrifuged; the ...
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Relationship between protein C antigen and anticoagulant activity during oral anticoagulation and in selected disease states
... Changes in the Mean Ratio of Protein C Anticoagulant Activity to Protein C Antigen, Protein C Amidolytic Activity, Factor VII Activity, and Factor X Activity in Patients Starting Oral An[r] ...
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Inhibition of the anticoagulant activity of protein S by prothrombin
... the anticoagulant, activated protein C ...S anticoagulant activity by ...the anticoagulant activity of APC measured in a Factor Xa recalcification time, was comparable using normal or ...
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Nonvitamin K antagonist oral anticoagulant activity: challenges in measurement and reversal
... the anticoagulant activity of apixaban and rivaroxaban (as measured by the anti-FXa assay) occurred within 2 to 5 minutes after administration of a bolus of ...
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Anticoagulant Activity of Methylated Coumarin Derivatives
... and anticoagulant drug are main inspiration of this ...antihypertensive activity of propranolol and anticoagulant activity of warfarin ...
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Lupus anticoagulant activity of autoimmune antiphospholipid antibodies is dependent upon beta 2 glycoprotein I
... similar anticoagulant properties, the relationship of beta 2GPI to lupus anticoagulant activity was ...lupus anticoagulant activity in the presence and absence of beta ...no ...
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Thrombomodulin modulates growth of tumor cells independent of its anticoagulant activity
... tion, though it is involved in secondary and tertiary structural assembly of the receptor. Despite possible changes in overall protein structure with the D lectin (M3) mutant, inherent in any mutational analysis, mutants ...
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Does plasmin have anticoagulant activity?
... thrombolytic activity. Studies in animals are suggestive of an anticoagulant effect of plasmin, but there is insufficient evidence to sup- port a definitive role of plasmin as an anticoagulant in ...
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THE EFFECT OF HUMAN PLASMA ON THE ANTICOAGULANT ACTIVITY OF HEPARIN
... that with normal platelet-free plasma containing very low concentrations of heparin, the anticoagulant effect of the heparin was overcome by increasing the amount of glass surface in con[r] ...
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Evidence of normal functional levels of activated protein C inhibitor in combined Factor V/VIII deficiency disease
... anticoagulant activity. The rate at which the amidolytic and anticoagulant activity of APC was neutralized in normal plasma was essentially identical to that observed in plasma obtained from ...
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... showed anticoagulant activity and among them, methanol extracts had the highest effect on increase of the PT (INR ...the anticoagulant activity of the tarragon leaves ...observed ...
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Bovine and porcine heparins: different drugs with similar effects on human haemodialysis
... duced anticoagulant activity achieved with pharmaceutical preparations of bovine heparin will guarantee similar pro- tection or efficiency as porcine heparin? In the case of car- diovascular surgeries, ...
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Research Paper Biochemical and Hemostatic properties of herbal plants used for the treatment of bleeding in Mali
... Medicinal plants traditionally used to treat bleeding event in Mali contained substances known for their pro-coagulant activity; others compounds having anticoagulant activity were also found in ...
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Characterization of a novel variant of the second domain of bikunin with increased leukocyte elastase inhibitory activity
... XIa, factor Xa, and leukocyte elastase were 182, 302, and 273 nM, respectively. Moreover, this tri- ple point mutant prolonged the activated partial thromboplastin time and moderately reduced leu- kocyte elastase-induced ...
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