Antifungal Agents
The ROLE OF HERBAL ANTIFUNGAL AGENTS FOR THE MANAGEMENT OF FUNGAL DISEASES: A SYSTEMATIC REVIEW
... numerous antifungal agents used clinically to treat fungal infections and can be broadly classified into five major classes, ...antimicrobial agents is the evaluation of plant extracts ...
7
Candida nivariensis, an Emerging Pathogenic Fungus with Multidrug Resistance to Antifungal Agents
... In 2005 and 2006, 16 fungal isolates with phenotypic simi- larities to C. nivariensis were submitted to the United Kingdom Mycology Reference Laboratory (MRL) for routine identifi- cation. In the study described here we ...
6
Synthesis of Some New Thioethers and 4 Thiazolidinones Bearing 3 (Pyridine 4' yl) 1,2,4 Triazino[5,6 b]Indole Moiety as Antifungal Agents
... Some new asymmetric thioethers 5 and 4-thiazolidinones 6 have been ob- tained from condensation of 5-formyl-3-(pyridin-4'-yl)-1,2,4-triazino[5,6- b ] indole (3) with halogenated aromatic amines followed by addition of ...
10
3D QSAR OF N SUBSTITUTED IMIDAZOLES AS ANTIFUNGAL AGENTS
... The CoMFA method has been applied to a set of antifungal agents active against C. albicans. The compounds taken for the study belong to chemically diverse families of imidazole derivative. The CoMFA model ...
20
Determination of minimum inhibitory concentrations of various antifungal agents in clinical isolates of Candida species
... Higher occurrence of NAC than C. albicans was noted. Overall, there was an excellent susceptibility pattern established against the commonly used antifungal agents. The outcome of the patients with ...
5
Effect of addition of antifungal agents on the ultimate tensile strength of temporary soft denture liners
... The feasibility of using a drug delivery system by incorporation of antifungal agents in denture base materials has been evaluated. 8,9 This system is even more advantageous when used in temporary soft ...
5
Molecular Docking Studies of Novel Aminopyrimidines as Potent Antifungal Agents
... vivo antifungal activity and are promising selective fungal N-myristoyltransferase inhibitors ...ideal antifungal agent should selectively inhibit the fungal enzyme ...as antifungal agents ...
9
Novel 2-pyrazoline derivatives as potential antibacterial and antifungal agents
... effective among the synthesized compounds against E. coli, (zone of inhibition 15 mm) and compound P05 was the most effective at 200 μg/ml among the synthesized compounds against P. aeruginosa, ( zone of inhibition 21 ...
5
SYNTHESIS AND BIOLOGICAL EVALUATION OF PYRAZOLINES AND THEIR DERIVATIVE AS ANTIMICROBIAL AND ANTIFUNGAL AGENTS
... A series of 2-Chloro-3-(3-aryl-4,5-dihydro-1H-pyrazole-5-yl)-7-(trifluoromethyl) quinoline was synthesized by the action of -[2-Chloro-7-(trifluoromethyl) quinoline-3-yl]-1-phenylpre-2-en-1- one on hydrogen hydrate. The ...
8
QSAR STUDIES ON BENZOXAZOLES AND OXAZOLO PYRIDINES AS ANTIFUNGAL AGENTS
... The developed QSAR model eq.2 describes the importance of connectivity and indicator descriptors with antimicrobial activity. According to the developed model MSD show the negative coefficient while IX and X1 show ...
8
In vitro activity of five antifungal agents against Candida albicans isolates, Sari, Iran
... Previous studies comparing in vitro antifungal activity against C. albicans in Iran have reported different results [27-29]. For instance, in vitro susceptibility test performed for C. albicans isolates by ...
6
Isolation, speciation and antifungal susceptibility testing of Candida isolates from various clinical specimens at a tertiary care hospital, Nepal
... four antifungal agents, clotrimazole and miconazole had not been used for clinical treatment but might be of interest for mycological ...an antifungal test to clotrimazole and miconazole as of ...
5
Recurrence of allergic bronchopulmonary aspergillosis after adjunctive surgery for aspergilloma: a case report with long-term follow-up
... The limitation of our case is that we were unable to detect the precise species of Aspergillus by culture of sputum, bronchial wash, or BALF. Additionally, molecu- lar identification of fungal species was not available ...
6
Chalcones bearing N, O, and S-heterocycles: Recent notes on their biological significances
... performance against M. tuberculosis H 37 Rv with MIC of 3.12 μg/ ml, same activity when compared to the Pyrazinamide as general medication for tuberculosis. Still in the same year, thiophene- based heterocyclic chalcones ...
13
Susceptibility to Fluconazole and Ketoconazole of Candida spp Isolated from Primary and Episodic Vulvovaginites by E Test (São Paulo, SP, Brazil)
... to antifungal agents of the isolated yeast of VVC, especially those of clinical significance, is important for detecting resistant mi- croorganisms and may contribute to medical management and consequent ...
10
DESIGN, SYNTHESIS AND ANTIFUNGAL ACTIVITY OF SOME BENZYL BENZIMIDAZOLE DERIVATIVES
... index unfortunately broad use of azoles has led to development of severe resistance. Toxicity associated with use of azoles has significantly reduced the efficacy of azole antifungal agents. This has led to ...
6
<p>Prevalence of <em>Candida</em> blood stream infections among children in tertiary care hospital: detection of species and antifungal susceptibility</p>
... Aim: The present study aimed to demonstrate the prevalence of candidaemia among children and to characterize the involved species and their susceptibility to antifungal agents. Methodology: Microbes were ...
8
Journal of Applied Pharmaceutical Science
... with antifungal agents cause side effects, there is a need to find a drug with more potency than the existing ...present antifungal agents such as caspofungin and echinocandin B, actidione, ...
6
EVALUATİON OF ANTİ-BİOFİLM AND ANTİFUNGAL ACTİVİTİES OF MENTHA LONGİFOLİA ESSENTİAL OİL AGAİNST CLİNİCAL ISOLATES OF CANDİDA ALBİCANS
... the antifungal resistance of Candida ...against antifungal agents cause significant challenges in combating biofilm- associated Candida ...to antifungal drugs, they provide protection against ...
5
Synthesis and Antifungal Evaluation of Spirostane Saponins
... novel antifungal agents have increased steadily with the rise and fall of AIDS-related mycoses, and the increased spectrum of fatal fungal infections that has accompanied changes in immunosuppressive ...new ...
239