antigen-presenting cells
Engineered hydrogen bonded glycopolymer capsules and their interactions with antigen presenting cells
... of antigen presenting cells (APC) and can interact with sugar ligands, (for example like those expressed on bacterial cell walls) and trigger or regulate immune ...
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Targeting of antigen presenting cells with mannosylated conjugates
... on antigen presenting ...peptide antigen are ...The antigen-presenting capacities of these conjugates are assessed and compared to the O-mannose ...
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Bioengineering of Artificial Antigen Presenting Cells and Lymphoid Organs
... Antigen-presenting cells (APCs) act as a link between the innate and adaptive immune ...an antigen, the APCs can display antigen-class I and II major histocompatibility complex (MHC) on ...
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Artificial antigen-presenting cells expressing AFP
... Professional antigen-presenting cells (APCs) are potent generators of tumor antigen-specific cytotoxic T lymphocytes (CTLs) for adoptive immunotherapy; however, generation of APCs is ...
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Selective Induction of Apoptosis in Antigen-Presenting Cells in Mice by Parapoxvirus ovis
... infected cells; (ii) interfering with the interaction between a cytokine and its receptor (poxviruses encode soluble cytokine receptors for tumor necrosis factor alpha [TNF-␣] and TNF-, IL-1, and importantly, ...
6
T cell hyperactivity in lupus as a consequence of hyperstimulatory antigen presenting cells
... T cells in vitro, compared with the B6 ...myeloid cells may dictate several of the phenotypes associated with systemic lupus, including ANA formation and T cell ...
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The labyrinth unfolds: architectural rearrangements of the endolysosomal system in antigen-presenting cells
... of antigen processing and peptide loading, although formal investi- gation thereof remains to be performed (Table ...inhibits antigen acquisition through non- specific phagocytosis and macropinocytosis [4], ...
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Innate Immune Responses in Fish: Antigen Presenting Cells and Professional Phagocytes
... T cells. As professional APCs, dendritic cells (DCs), monocyte/macrophages and B cells, engulf pathogens and process antigen to ...Following antigen processing, APCs present peptides by ...
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Antigen-presenting cells of the gastrointestinal tract
... The properties they share with the dendritic cell lineage include morphology, physical properties low density and non-adherent, high level expression of HLA-DR surface antigens, the expr[r] ...
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The role of antigen presenting cells in the induction of HIV 1 latency in resting CD4+ T cells
... CD3 (7 μ g/ml; Beckman Coulter), in RF10 media sup- plemented with CD28 (5 μ g/mL; BD Biosciences), IL-7 (50 ng/mL; Sigma, St Louis, MO, USA), IL-2 (5U/mL; Roche), with (post-integrated latency) or without (total ...
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Interaction of the proteins which regulate MHC class II-mediated antigen presentation by antigen presenting cells
... Immunoprecipitations with the anti-H2-M antibody K553 (Fig 3.4) showed the greatest difference in the molecules precipitated as a function of the two different detergents employed. Greater numbers of bands or a higher ...
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An immunohistochemical study of CD83- and CD1a-positive dendritic cells in the decidua of women with recurrent spontaneous abortion
... potent antigen-presenting cells (APC) in the immune system with the unique ability to induce primary immune responses ...stem cells, migrate through the blood, and then disperse widely in ...
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Hellwig, Alice (2007): Mechanisms of Hsp70-Mediated Antigen Cross-Presentation. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... dying cells, possibly protecting them from premature degradation in the blood stream, but indeed mediates the uptake of these peptides by cells capable of ...of antigen presenting cells ...
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A novel mycobacterial Hsp70-containing fusion protein targeting mesothelin augments antitumor immunity and prolongs survival in murine models of ovarian cancer and mesothelioma
... cancer cells. Numerous strat- egies that involve tumor antigen-specific and non- specific activation of the immune system have been ...[1-3]. Antigen-specific active immunotherapy is ex- pected to be ...
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Management of hypersensivity pneumonitis
... APC: Antigen presenting cells; BALF: Broncho-alveolar lavage fluid; BFL: Bird- fancier lung; CTLA-4: Cytotoxic T-Lymphocyte Antigen 4; DCs: Dendritic cells; DLCO: Diffusing capacity; ...
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“Probiotics Usage and Safety Concerns - A Review” by Shailendra Pandey, Shilpa Pahwa, Chitra Gupta, India.
... through many different pathways such as effects on enterocytes, antigen presenting cells (including both circulating monocytes and local dendrite cells), effectors T and B[r] ...
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Specific tolerance to an acetylcholine receptor epitope induced in vitro in myasthenia gravis CD4+ lymphocytes by soluble major histocompatibility complex class II peptide complexes
... T cells have been cloned from MG patients, and in this study, we have induced long-lasting tolerance in vitro in one particular clone (PM-A1) with a known peptide epitope (alpha 144-163) and MHC class II ...
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The Role of the GTPase Rho in T cell Adhesion and Migration
... only cells with low TCR levels were selected in LckC3/P14 TCR double-transgenic ...only cells with a low level of TCR can ‘escape’ to the ...by antigen-presenting cells in the thymus ...
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Production Large Array of Cytokines by Mouse Dendritic Cells Pulsed with Hepatitis C Virus Pseudo-particles
... Dendritic cells (DC), the most potent antigen presenting cells (APC) found at trace levels in lymphoid and nonlymphoid tissues, are required for the priming of naive T ...dendritic ...
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Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer
... B cells, and likely target stromal cells, but not tumor cells ...B cells when delivered ...immune cells — not on adaptive immune cells, which PD-1 blockade targets — we ...
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