antigen recognition
Blood Group Antigen Recognition via the Group A Streptococcal M Protein Mediates Host Colonization
... group antigen structures are expressed by a range of host cells (2, ...group antigen structures may be a function of throat-tropic ...group antigen precursor LNT and H antigen type I in an M1 ...
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Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition
... samples. The mean spontaneous lysis for target cells in the culture medium was always < 20%, and the variation from the mean specifi c lysis was < 10%. HLA peptide-binding assays. To assess peptide binding to ...
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Structural basis of antigen recognition by T lymphocytes Implications for vaccines
... Because T cells recognize peptide fragments of proteins that have primary amino acid sequence and secondary structure such as a-helices and :-turns but largely do not retain the tertiary[r] ...
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A coiled conformation of amyloid-β recognized by antibody C706
... of antigen recognition and the preferential A β conformations, we determined the crystal structure of murine antibody C706 in complex with the N-terminal A β 1 – 16 peptide ...
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Humanized Monoclonal Antibody for Prevention of Respiratory Syncytial Virus Infection
... that grafts an antigen recognition site derived from a mouse monoclonal antibody onto a human immuno- globulin backbone. The mouse monoclonal antibody used to create palivizumab recognizes a protective ...
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Detection of Schistosoma mansoni Membrane Antigens by Immunoblot Analysis of Sera of Patients from Low-Transmission Areas
... membrane antigen that correlated to resistance in ...tegumental antigen (1) and a calcium binding protein of 8 kDa known as Sm8 (2, 20) were specifically recognized in immunoblotting with sera of schisto- ...
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CD4 T cell–mediated cardiac allograft rejection requires donor but not host MHC class II
... can persist for at least several months in C2D hosts (40), a result consistent with our own study. Further- more, in the present study, the recipient does contain MHC class II expressed by the donor transplant, which ...
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Review Article Targeted therapy against hepatocellular carcinoma
... extracellular antigen recognition domain scFv and mediate the T-cell activation through the intracellular TCR signal transduction ...T-cells recognition to unrestricted from human leukocyte ...
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Human Antibody Responses to Emerging Mayaro Virus and Cocirculating Alphavirus Infections Examined by Using Structural Proteins from Nine New and Old World Lineages
... antibody recognition, yet we did not observe significant antigen cross-reactivity with serum samples from human MAYV infections or those of any other Semliki Forest complex ...serum recognition of ...
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Alveolar epithelial cell chemokine expression triggered by antigen specific cytolytic CD8+ T cell recognition
... transfer (11). Since TNF-α (in its soluble form) is known to induce expression of a variety of inflamma- tory mediators in respiratory epithelial cells (16–18), we hypothesized that there may be a noncytotoxic com- ...
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A Novel Redox Method for Rapid Production of Functional Bi-Specific Antibodies For Use in Early Pilot Studies
... of antigen recognition by hybrid ...simultaneous recognition of anti-rat IgG and anti-mouse IgG in ELISA assay 1 as visualized by an increase in the OD reading at 450 nm compared to parental ...mAbs. ...
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Characterization of the binding pattern of human aquaporin-4 autoantibodies in patients with neuromyelitis optica spectrum disorders
... of antigen recognition, we tested 47 AQP4-IgG positive serum samples and 49 follow-up samples for their capability to bind AQP4-M1 and AQP4-M23 wild-type isoforms and six AQP4-M23 extracellular loop ...
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CAR therapy: the CD19 paradigm
... of antigen-specific T cells would be feasible, although cum- ...ates antigen recognition, known as the T cell receptor (TCR) (4–6), led to transgenic mouse studies that demonstrated that ...
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T cell immunoglobulin domain and mucin domain-3 as an emerging target for immunotherapy in cancer management
... Emerging evidence has unveiled the indispensable role of the host immune system in defending itself from arising tumors. The host immune system acts to detect and eliminate tumors in three ways: 1) immune cells protect ...
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Fine mapping two distinct antigenic sites on simian virus 40 (SV40) T antigen reactive with SV40-specific cytotoxic T-cell clones by using SV40 deletion mutants.
... We identified amino acids in the amino-terminal half of SV40 T antigen that are essential for the recognition of antigenic sites by these CTL clones by using H-2b cells transformed by mu[r] ...
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Speech Recognition for English Language Pattern Recognition Approach
... In conclusion we are able to say that if we increase the size of vocabulary there will be effect on the output. In this paper I discussed all the aspect that can affect our system during voice to text conversion. Here we ...
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Organizational Accessibility and Community Connections: Examining Changes in the Spatial Proximity of Pubic Housing Residents to Social Service Providers and Providers' Responses to Redevelopment
... accomplish this, we exposed infected cells to PBMC at 50:1 effector: target ratio and deter-‐ mined NK cell cytotoxicity by measuring perforin and granzyme B release. Generally, NK cell (during primary infection) and ...
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Disease associated human histocompatibility leukocyte antigen determinants in patients with seropositive rheumatoid arthritis Functional role in antigen specific and allogeneic T cell recognition
... in antigen-restricted T cell recognition we generated T cell clones from RA patients specific for mycobacterial antigens, Epstein-Barr virus antigens, and tetanus ...the recognition of ...
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Production and Preclinical Evaluation of Plasmodium falciparum MSP-119 and MSP-311 Chimeric Protein, PfMSP-Fu24
... 4°C. Antigen-coated plates were washed and blocked with 2% low-fat milk in PBS (pH ...to antigen- coated wells in duplicate and incubated for 1 h at room ...
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Engineering T Cells Specific for a Dominant Severe Acute Respiratory Syndrome Coronavirus CD8 T Cell Epitope
... For recognition of the endogenous SARS antigen, the SARS NP44-specific T cell clone and NP44 TCR-transduced T cells were incubated with target cells infected with a vaccinia virus construct expressing the ...
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