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antimicrobial peptides

Antimicrobial Peptides in the Oral Environment: Expression and Function in Health and Disease

Antimicrobial Peptides in the Oral Environment: Expression and Function in Health and Disease

... Antimicrobial peptides are under investigation for control of oral infections. One such drug is Iseganan, an analog of protegrin-1, a porcine cathelicidin, which has broad spectrum bactericidal activity. ...

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Peptide consensus sequence determination for the enhancement of the antimicrobial activity and selectivity of antimicrobial peptides

Peptide consensus sequence determination for the enhancement of the antimicrobial activity and selectivity of antimicrobial peptides

... new antimicrobial agents to tackle the problem of antimicrobial ...moderate antimicrobial activity with significant toxicity against mammalian ...enhanced antimicrobial potency and selectivity ...

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Lipid coated liquid crystal droplets for the on chip detection of antimicrobial peptides

Lipid coated liquid crystal droplets for the on chip detection of antimicrobial peptides

... For many decades, liquid crystal (LC) materials have been widely used in industry for LC display (LCD) applications, due to their well-known electrooptic modulation effects. More re- cently, LC materials have shown great ...

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Degradation of naturally occurring and engineered antimicrobial peptides by proteases

Degradation of naturally occurring and engineered antimicrobial peptides by proteases

... current antimicrobial peptides should be susceptible to proteolytic ...timicrobial peptides: Griffithinsin, RC-101, LL-37, LSA-5, PSC-RANTES and DJ007 were degraded by commercially available ...

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Generation of novel cationic antimicrobial peptides from natural non-antimicrobial sequences by acid-amide substitution

Generation of novel cationic antimicrobial peptides from natural non-antimicrobial sequences by acid-amide substitution

... As a trial study, the pro-regions of nematode cecro- pins were selected as parent sequences. Nematode cecropins are natural antimicrobial peptides [13-15]. Four nematode cecropins (P1-P4) have been ...

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Profound Study for Functions of Antimicrobial Peptides in Prevention of Oral Disease

Profound Study for Functions of Antimicrobial Peptides in Prevention of Oral Disease

... and antimicrobial peptides in saliva contribute to the chemical shield on the surface of the oral mucosa, the intact stratified squamous epithelium presents a physical barrier ...

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Lipid coated liquid crystal droplets for the on-chip detection of antimicrobial peptides

Lipid coated liquid crystal droplets for the on-chip detection of antimicrobial peptides

... For many decades, liquid crystal (LC) materials have been widely used in industry for LC display (LCD) applications, due to their well-known electrooptic modulation effects. More re- cently, LC materials have shown great ...

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CAMP: a useful resource for research on antimicrobial peptides

CAMP: a useful resource for research on antimicrobial peptides

... years, antimicrobial peptides (AMPs) have attracted lot of atten- tion as a substitute for conventional antibiotics ...These peptides cause cell death either by disrupting the microbial cell ...

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An Antiviral Role for Antimicrobial Peptides during the Arthropod Response to Alphavirus Replication

An Antiviral Role for Antimicrobial Peptides during the Arthropod Response to Alphavirus Replication

... transcriptional changes found in the microarray by the Imd and Jak-STAT pathways. We analyzed the 2-kb-upstream sequences of all 95 SINrep-sensitive genes for Rel and STAT binding sites. Thirty- eight genes had at least ...

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SPS neutralization in tissue samples for efficacy testing of antimicrobial peptides

SPS neutralization in tissue samples for efficacy testing of antimicrobial peptides

... of antimicrobial agents requires neutralization of residual antimicrobial activity in the samples before microbiological assessment of the number of surviving ...the antimicrobial activity of ...

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Technological Potential of Antimicrobial Peptides: a Systematic Review

Technological Potential of Antimicrobial Peptides: a Systematic Review

... period, the search for new substances with action against pathogenic microorganisms has become a constant between researchers in the pharmaceutical area. Among the substances studied are the antimicrobial ...

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Antimicrobial peptides and nitric oxide production by neutrophils from periodontitis subjects

Antimicrobial peptides and nitric oxide production by neutrophils from periodontitis subjects

... these peptides detected between healthy and diseased sites, although these defensins seem to be more abundant in healthy gingival crevicular fluid ...of antimicrobial peptides compared to neutrophils ...

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Epithelial antimicrobial peptides in host defense against infection

Epithelial antimicrobial peptides in host defense against infection

... A first line of defense against pathogenic insult is called the innate immune system, which is followed by acquired immune responses associated with the activation of T and B cells aimed against specific antigens [1,2 • ...

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Effects of cationic antimicrobial peptides on Candida and Saccharomyces species

Effects of cationic antimicrobial peptides on Candida and Saccharomyces species

... The echinocandins are a relatively new class of antifungals that are active against Candida and Aspergillus species. They act by damaging the cell wall, inhibiting the synthesis of 1,3-β glucan. There are currently no ...

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FISH MUCUS: A NEGLECTED RESERVOIR FOR ANTIMICROBIAL PEPTIDES

FISH MUCUS: A NEGLECTED RESERVOIR FOR ANTIMICROBIAL PEPTIDES

... the antimicrobial resistance using fish derived antimicrobial ...these antimicrobial peptides, their very broad spectrum activity against pathogens keeps them among promising antibiotics as ...

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Multifunctional host defense peptides: functional and mechanistic insights from NMR structures of potent antimicrobial peptides

Multifunctional host defense peptides: functional and mechanistic insights from NMR structures of potent antimicrobial peptides

... the antimicrobial peptides might be required to form oligomeric ...of antimicrobial peptides are not easily obtain- ...[72,73]. Antimicrobial peptide studies in such lipid environments ...

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The application of antimicrobial peptides as growth and health promoters for swine

The application of antimicrobial peptides as growth and health promoters for swine

... performance. Antimicrobial peptides (AMPs) are part of the nonspecific defense system and are natural antibiotics produced by plants, insects, mammalians, and micro-organisms as well as by chemical ...

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PLANT ANTIMICROBIAL PEPTIDES: A NOVEL APPROACH AGAINST DRUG RESISTANT MICROORGANISMS

PLANT ANTIMICROBIAL PEPTIDES: A NOVEL APPROACH AGAINST DRUG RESISTANT MICROORGANISMS

... These peptides contain cyclic cystine knot (CCK) motif created by six conserved cysteine ...from antimicrobial activity, cyclotides also shows insecticidal and anti- cancerous activity 74 ...Two ...

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Host Antimicrobial Peptides: the promise of new treatment strategies against Tuberculosis

Host Antimicrobial Peptides: the promise of new treatment strategies against Tuberculosis

... of antimicrobial resistance to its treat- ...of antimicrobial peptides (AMPs) remains ...endogenous antimicrobial proteins and peptides as ancient players of the human host defense ...

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Natural Antimicrobial Peptides: Pleiotropic  Molecules in Host Defense

Natural Antimicrobial Peptides: Pleiotropic Molecules in Host Defense

... of antimicrobial peptides in COPD exacerbations were also ...the antimicrobial peptides SLPI, elafin, pentraxin, LL-37, α-defensins and β-defensin-2, and the protease neutrophil elastase were ...

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