Antimycobacterial Activity
Quantitative structure activity relationship of molecules constituent of different essential oils with antimycobacterial activity against Mycobacterium tuberculosis and Mycobacterium bovis
... With all the biological activities (MIC for mycobacteria) and the calculated theoretical descriptors obtained, a QSAR study was carried out by generating genetic algo- rithms using the Mobydigs Software [24]. The quality ...
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Synthesis of Benzo[G]Quinoxaline-5,10-Dione Based Pyridine Derivatives and their Antimycobacterial Activity
... Ten compounds 6a, 6b, 6c, 6d, 6f, 6g, 6h, 6i, 6j and 6k were submitted for their antimycobacterial activity against Mycobacterium tuberculosis H 37 Rv (MTCC-200) by L.J. Slope (Conventional) Method 24- 25 . ...
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ANTIBACTERIAL AND ANTIMYCOBACTERIAL ACTIVITY OF MEDICINAL ORCHID OF ARUNACHAL PRADESH
... ABSTRACT: Orchidaceae, one of the largest families of plant kingdom, possesses high aesthetic, medicinal and economic value. However, medicinal properties of orchids has not been investigated to its fullest potential. ...
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Modular Synthesis of Diverse Natural Product-like Macrocycles: Discovery of Hits with Antimycobacterial Activity
... Abstract: A modular synthetic approach was developed in which variation of the triplets of building blocks used enabled systematic variation of the macrocyclic scaffolds prepared. The approach was demonstrated in the ...
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Acetone leaf extracts of some South African trees with high activity against Escherichia coli also have good antimycobacterial activity and selectivity index
... antimicrobial activity against Escherichia coli to determine the potency, effi- cacy and safety of acetone tree leaf extracts against three fast growing Mycobacterium ...the antimycobacterial ...
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Determination of the Antimycobacterial Activity of the Ethyl Acetate Fractions and Isolated Compounds from the Roots of Allexis batangae and Allexis obanensis
... To test for the antimycobacterial activity, the ethyl acetate fractions and the isolated compounds were tested against M. smegmatis using the microplate dilution method. Each sample was dissolved in 10 % ...
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Evaluation of the antimycobacterial activity of crude extracts and solvent fractions of selected Ethiopian medicinal plants
... investigate antimycobacterial activity of crude extract of Carissa edulis, Otostegia integrifolia, Persea americana, Pterolobium stellatum and Vernonia amygdalina as well as fractions of the most active ...
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SYNTHESIS OF BENZO[G]QUINOXALINE 5,10 DIONE BASED PYRAZOLINE DERIVATIVES AND THEIR ANTIMYCOBACTERIAL ACTIVITY
... ABSTRACT: Eleven new compounds belonging to series 7-[5- (substituted) phenyl - 4, 5-dihydro-1H-pyrazol-3-yl]-2,3-diphenyl-5H, 10H - benzo[g] quinoxaline - 5, 10 - dione (Compound 7a-k) were synthesized by multistep ...
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Antimycobacterial activity of Gynura procumbens leaves extract against Mycobacterium tuberculosis
... the antimycobacterial activity of ...and antimycobacterial evaluation was conducted using microscopic observation drug susceptibility ...has antimycobacterial activity against ...
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Antimycobacterial activity of Brazilian Amazon plants extracts
... The antimycobacterial activity of extracts was determined preliminarily by the Resazurinmicrotiter assay method (REMA), in a fixed concentration of 200 øg/mL, for the three strains of ...
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Synthesis and in vitro Evaluation of the Antimycobacterial Activity of N-aryl-1,4-dihydropyridine-3,5-dicarboxamides
... Dihydropyridines (DHPs) with carboxamides in the 3 and 5 positions show anti-tuberculosis activity. The purpose of the present study was to synthesize new DHPs that would possibly possess anti-tuberculosis ...
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Extracts of six Rubiaceae species combined with rifampicin have good in vitro synergistic antimycobacterial activity and good anti inflammatory and antioxidant activities
... One of the manifestations of inflammation is oxidative stress, and the pathways that generate the mediators of inflammation are all induced by oxidative stress [5]. Most of the potentially harmful effects of oxygen are ...
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Solvent free synthesis of alkyl 2 (dialkylamino) 4 phenylthiazole 5 carboxylates derivatives and in vitro antimycobacterial activity of these compounds against Mycobacterium smegmatis
... anti-mycobacterial activity of compounds 8a, 8c, 8g, 8f, 8i and 8j makes them suitable hits for additional In vitro and In vivo evaluations, in order to develop new anti mycobacterial drugs or pro drugs with ...
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Synthesis, antimycobacterial activity and docking studies of L-proline derived hydrazones
... potential antimycobacterial drugs ...front-line antimycobacterial drugs such as Rifampin and INH pose serious concerns [6-8], which clearly indicates the need for more effective drugs for the efficient ...
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Combatting AMR : photoactivatable ruthenium(ii) isoniazid complex exhibits rapid selective antimycobacterial activity
... bacterium E. coli and showed only slight activity once photo- irradiated with blue light for 2 h against the Gram-positive bacterium B. subtilis at concentrations of 100 mM and 200 mM. The high photoactivity of 1 ...
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ANTIMYCOBACTERIAL ACTIVITY OF FOLIOSE LICHENS ON PLANT AND ANIMAL PATHOGENS
... Acetone, methanol and light petroleum extracts of Usnea ghattensis showed activity against B. subtilis and S.aureus 17 which was found to be attributed that the lichen compound’s chief function on inhibiting the ...
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In vitro differentiation of human macrophages with enhanced antimycobacterial activity
... From this point on we used the following framework for culture of MDMs: 2 weeks of differentiation in RPMI containing 40% human plasma, with replacement of 30% of the medium every 3–4 da[r] ...
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Ursolic and oleanolic acids as antimicrobial and immunomodulatory compounds for tuberculosis treatment
... less activity against non-tuberculous mycobac- teria, with the MIC value of 100 μg mL -1 ...the antimycobacterial activity has not yet been determined, it has been proposed that UA and OA can produce ...
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Characterization of n Hexane sub fraction of Bridelia micrantha (Berth) and its antimycobacterium activity
... of antimycobacterial drugs for example from medicinal ...vitro antimycobacterial activity of n-Hexane sub-fraction from Bridelia micrantha (Berth) against MTB H 37 ...
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Biogenic Silver Nanoparticles as Potential Agent against Mycobacterium Tuberculosis
... Biogenic synthesis of silver nanoparticles is green, ecofriendly and inexpensive technology. In present study based on results we conclude that aqueous extracts of flower of can be used for synthesis of Silver ...
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