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antineoplastic activity

New Green Synthesis and Antineoplastic Activity of Bis (3 Arylimidazolidinyl 1) Methanes

New Green Synthesis and Antineoplastic Activity of Bis (3 Arylimidazolidinyl 1) Methanes

... anti-tumor activity of the series of bis (3-arylimidazolidinyl-1) methanes 1 - 6 are ...showed antineoplastic activity, 60%, 82% and 89% inhibition growth cell respectively on the human colon cell ...

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Development of dihydrochalcone-functionalized gold nanoparticles for augmented antineoplastic activity

Development of dihydrochalcone-functionalized gold nanoparticles for augmented antineoplastic activity

... augmented antineoplastic activity resulting from the conjugation of the drugs to the AuNP ...anticancer activity was observed The flow- cytometry assays revealed that the pure forms of the drug ...

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THE ANTINEOPLASTIC ACTIVITY OF ECHITAMIDINE N OXIDEGLUCOPYRANOSIDE ISOLATED FROM STEM BARK EXTRACT OF ALSTONIA SCHOLARIS IN KB CELLS

THE ANTINEOPLASTIC ACTIVITY OF ECHITAMIDINE N OXIDEGLUCOPYRANOSIDE ISOLATED FROM STEM BARK EXTRACT OF ALSTONIA SCHOLARIS IN KB CELLS

... the antineoplastic activity of isolated bioactive molecule Echitamidine-N-Oxide-19-0-β-D- Glucopyranoside in cultured KB cells from the chloroform fraction of Alstonia ...

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Comparative Analysis of the Antineoplastic Activity of C60 Fullerene with 5 Fluorouracil and Pyrrole Derivative In Vivo

Comparative Analysis of the Antineoplastic Activity of C60 Fullerene with 5 Fluorouracil and Pyrrole Derivative In Vivo

... Abstract The antitumor activity of pristine C60 fullerene aqueous solution C60FAS compared to 5-fluorouracil 5-FU and pyrrole derivative 1-4-Cl-benzyl-3-Cl-4-CF3-fenylamino-1H-pyrrol-2.5[r] ...

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IN SILICO STUDY ON ANTINEOPLASTIC ACTIVITY OF MODIFIED PLANT BASED CHEMICAL INHIBITORS OF ANTI APOPTOTIC PROTEINS

IN SILICO STUDY ON ANTINEOPLASTIC ACTIVITY OF MODIFIED PLANT BASED CHEMICAL INHIBITORS OF ANTI APOPTOTIC PROTEINS

... Cancer is one of the major disease currently affecting millions people worldwide and the number is growing rapidly ,Present study was aimed at finding a better alternative to natural chemical an anticancer ...

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Evaluation of the Antineoplastic Activity of L-rhamnose in vitro. A Comparison with 2-deoxyglucose

Evaluation of the Antineoplastic Activity of L-rhamnose in vitro. A Comparison with 2-deoxyglucose

... reported the effect of intravenously administered L-fucose on the size of a rat solid mammary adenocarcinoma in vivo (25, 41) as well as the efficacy of this deoxysugar in vitro (21, 24, 28, 40), no significant ...

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Original Article Antineoplastic activity of metformin on the A549 human lung carcinoma cell line in vitro

Original Article Antineoplastic activity of metformin on the A549 human lung carcinoma cell line in vitro

... In summary, metformin significantly inhibits the growth of human lung carcinoma A549 cells and potentiates cisplatin activity. Metformin possibly exerts this inhibitory effect by inducing cell cycle arrest at the ...

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Curcumin C3 complex®/Bioperine® has antineoplastic activity in mesothelioma: an in vitro and in vivo analysis

Curcumin C3 complex®/Bioperine® has antineoplastic activity in mesothelioma: an in vitro and in vivo analysis

... As a first line strategy, we performed an in vitro study to evaluate the effects of C3 Complex® in three different MM cell lines: MSTO, NCI, and Mes-2. The results showed that CBP compar[r] ...

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Indicators of oxidative and nitrosative stress and activity of enzymes of nitric oxide metabolism in rats treated with 4-thiazolidinone derivatives possessing antineoplastic activity

Indicators of oxidative and nitrosative stress and activity of enzymes of nitric oxide metabolism in rats treated with 4-thiazolidinone derivatives possessing antineoplastic activity

... the activity of enzymes of the nitric oxide metabolism in blood of rats treated with such ...the activity of either ino-synthase or no- reductase under the action of doxorubicin, while Les-3288 and Les-3882 ...

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Exceptional antineoplastic activity of a dendritic-cell-targeted vaccine loaded with a Listeria peptide proposed against metastatic melanoma

Exceptional antineoplastic activity of a dendritic-cell-targeted vaccine loaded with a Listeria peptide proposed against metastatic melanoma

... Vaccination with dendritic cells (DCs) is proposed to induce lasting responses against melanoma but its survival benefit in patients needs to be demonstrated. We propose a DC-targeted vaccine loaded with a Listeria ...

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A systematic multicellular spheroids screening approach lead to the identification of antineoplastic activity in three different plant extracts from the Egyptian flora

A systematic multicellular spheroids screening approach lead to the identification of antineoplastic activity in three different plant extracts from the Egyptian flora

... Pro-apoptotic activity determination on HCT116 monolayers 10000 cells per well were seeded in 96-well plates and left for ...Pro-apoptotic activity was determined using the M30 CytoDeath ELISA assay (VLV ...

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In Vitro Assessment of the Antineoplastic Activity of Doxorubicin Combined With Gemcitabine in a Nanoparticle

In Vitro Assessment of the Antineoplastic Activity of Doxorubicin Combined With Gemcitabine in a Nanoparticle

... antitumor activity of DOX in combination with GEM encapsulated in nanoemulsion (NE) against various cancer cells (HeLa cervical cancer cells, HCT116 colon cancer cells and A549 non-small cell lung cancer cells) ...

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Taurolidine cooperates with antineoplastic drugs in neuroblastoma cells

Taurolidine cooperates with antineoplastic drugs in neuroblastoma cells

... Neuroblastoma is the most common extracranial tumor in childhood. Outcome of stage 4 disease remains poor and the development of novel therapeutic approaches is thus urgently needed. Taurolidine (TRD), originally ...

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A PROMISING ANTINEOPLASTIC DRUG – METFORMIN (AN AMPK ACTIVATOR) FOR THE FUTURE

A PROMISING ANTINEOPLASTIC DRUG – METFORMIN (AN AMPK ACTIVATOR) FOR THE FUTURE

... Metformin asantidiabetes and anticancer: Interest in the potential relevance of biguanides to neoplastic diseases was stimulated by a report describing reduced cancer burden in diabetic patients treated with metformin as ...

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Original Article Rosiglitazone induces apoptosis on human bladder cancer 5637 and T24 cell lines

Original Article Rosiglitazone induces apoptosis on human bladder cancer 5637 and T24 cell lines

... a antineoplastic activity by inducing apoptosis and cell cycle ...potential antineoplastic activity in human bladder cancer cell lines, and the underlying mechanism was mediated, at least ...

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In vitro and in vivo Evaluation of Flavonoids from Heliotropium ellipticum Exudate for Antioxidant, Antineoplastic and Cytotoxic Activities II

In vitro and in vivo Evaluation of Flavonoids from Heliotropium ellipticum Exudate for Antioxidant, Antineoplastic and Cytotoxic Activities II

... The antineoplastic activity was assessed by PCV ...their antineoplastic activity and found that chrysin demonstrated maximum inhibition ...

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Isolation of Lactobacillus salivarius from Children and Purification of Bacteriocin to Inhibition Cancer Cell in Vitro

Isolation of Lactobacillus salivarius from Children and Purification of Bacteriocin to Inhibition Cancer Cell in Vitro

... have antineoplastic activity against a variety of human tumor and animal tumor cell lines in ...antimicrobial activity against indicator strain Streptococcus aureus and by used sodium phosphate ...

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Original Article Doxorubicin-loaded Pluronic P123-PEG2000-DSPE micelles reverse the drug resistance of breast cancer cells

Original Article Doxorubicin-loaded Pluronic P123-PEG2000-DSPE micelles reverse the drug resistance of breast cancer cells

... and antineoplastic activity including dynamic light scattering method, MTT, immunofluorescence, Western blot and Annexin V-PI in BC MCR-7 cells and MCF-7R, a BC drug resistant cell ...

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Complexes of Co(II), Cu(II) and Ni(II) with Antineoplastic Agent Imatinib Mesylate: Synthesis, Characterization and Biological Activity

Complexes of Co(II), Cu(II) and Ni(II) with Antineoplastic Agent Imatinib Mesylate: Synthesis, Characterization and Biological Activity

... Antimicrobial activities were investigated by diffusion method for reference bacterial strains E.coli, E. faecalis, S. aureus, B. subtilis, L. monocytogenes and P. aeruginosa. Antifungal activity of the complex ...

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The antineoplastic properties of FTY720: Evidence for the repurposing of fingolimod

The antineoplastic properties of FTY720: Evidence for the repurposing of fingolimod

... phosphatase activity that participates in a range of cellular mecha- nisms, including regulation of the cell cycle, apoptosis and cellular ...PP2A activity can lead to the development of colorectal and lung ...

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