Antiplasmodial Activity
AN IN VIVO EVALUATION OF ANTIPLASMODIAL ACTIVITY OF AQUEOUS AND ETHANOLIC LEAF EXTRACTS OF AZADIRACHTA INDICA IN PLASMODIUM BERGHEI INFECTED BALB/c MICE
... The antiplasmodial activity of both ELEAI and ALEAI were comparable to those of ...superior antiplasmodial activity, the result suggests that the leaf extracts of ...
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In vitro antiplasmodial activity of crude extracts of Tetrapleura tetraptera and Copaifera religiosa
... Antiplasmodial activity was analyzed with the DELI method (double-site enzyme-linked lactate dehydrogen- ase immunodetection assay) a pLDH measurement with an ELISA method as previously described ...
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Radical Scavenging and Antiplasmodial Activity of Polygonum senegalense of Benin
... better antiplasmodial activity than the Artemisinin-based Combination Therapies (ACTs), the reference drug most used nowadays for the treatment of ...
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CHEMICAL COMPOSITION AND IN VITRO ANTIPLASMODIAL ACTIVITY OF ESSENTIAL OILS OF LEAVES AND FLOWERS OF ALPINIA ZERUMBET GROWN IN CUBA
... Alpinia zerumbet (Pers.) B.L. Burtt & R. M. Smith was recommended to treat malaria fevers before eradication in Cuba. The chemical analysis identified 68 and 75 volatile compounds of the essential oils isolated from ...
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In Vitro Antiplasmodial Activity and Cytotoxicity of Leaf Extracts from Jatropha Tanjorensis
... in vitro by using a 3D7 chloroquine sensitive clone of NF-54 isolate of Plasmodium falciparum. Parasite growth inhibition was estimated based on the 48 hours microassay technique with the extracts dissolved in either ...
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Synthesis, characterization, purity verification, antiplasmodial activity and toxicity against Artemia salina Leach of salicylhydrazones and p tosylhydrazones from S (+) carvone and arylketones
... In this study, eight hydrazone derivatives were synthesized, purified and characterized. Their biological activities were evaluated and products showed interesting antiplasmodial activity on the studded ...
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ANTIPLASMODIAL ACTIVITY OF ARGEMONE MEXICANA: AN IN VIVO AND IN VITRO STUDY
... vitro antiplasmodial activity and enhanced the antiplasmodial activity in mice when co-administered with crude alkaloidal extract suggest that berberine contains the active ...
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New Cassane Diterpenoids from Caesalpinia sappan and Their Antiplasmodial Activity
... Antiplasmodial activity in vitro was determined by means of the microculture radioisotope technique based on the method described by Desjardins [13]. The parasite P. falciparum (K1, multidrug-resistant ...
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Phytochemical screening and Antiplasmodial activity of Mundulea antanossarum seeds from Madagascar
... and antiplasmodial activities of Mundulea antanossarum seeds extract using two standardized parasites strains (Plasmodium falciparum FcM29-Cameroon and ...vitro antiplasmodial activity of the plant ...
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IN VITRO ANTIPLASMODIAL ACTIVITY OF NATIVE INDIAN SEAWEED SARGASSUM SP
... GC-MS analysis was followed by observing potent antiplasmodial activity in treated crude extracts. GC analysis of was performed with GC-Clarus 500 Perkin Elmer using elite 5MS columns. The qualitative and ...
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Antiplasmodial Activity, Cytotoxicity and Phytochemical Composition of Juticia Betonica, Vernonia Dumicola and Rotheca Myricoides and Their Combinations
... to antiplasmodial drugs and this has been a challenge in control and treatment of the disease through chemotherapy, something that necessitates the continuous search for alternative antiplasmodial ...their ...
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The antiplasmodial activity of chalcone derivative through the inhibition of haemozoin formation and the induction of stomatocytes formation
... antiplasmodial activity. In this study, we reported in vivo antiplasmodial activity of this compound against Plasmodium berghei infected ...
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ANTIPLASMODIAL ACTIVITY OF AGANOSMA CYMOSA
... schizontocidal activity of the crude extract against ...rats. Antiplasmodial activity of the test extract was performed in a 4-days suppressive standard ...
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In vitro and in vivo antiplasmodial activity of oxyresveratrol and artonine isolated from two Artocarpus plants in Indonesia
... This study is believed to report the first antiplasmodial activity of two compounds, oxyresveratrol and ar tonin E isolated from Ar tocar pus plants, A. dadah and A. rigida, respectively, from Indonesia. It ...
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Antiplasmodial activity of Indigofera spicata root extract against Plasmodium berghei infection in mice
... antioxidant activity have known anti- microbial activity, ...antioxidant activity which might support its antidia- betic, anticancer, antidiarrhoeal activities [19, 30] and the current anti-malarial ...
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In vivo antiplasmodial activity and toxicological assessment of hydroethanolic crude extract of Ajuga remota
... prophylactic activity on ...vivo antiplasmodial activity can be classified as moderate, good, and very good if an extract displayed percentage parasitaemia suppression equal to or greater than 50% at ...
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In vitro antiplasmodial activity of cepharanthine
... In this work, the bisbenzylisoquinoline, called cephar- anthine, exerted an antiplasmodial activity against four strains of P. falciparum. There is no bisbenzylisoquinoline currently used in the treatment ...
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Identification and characterization of the antiplasmodial activity of Hsp90 inhibitors
... potential antiplasmodial target ...stronger antiplasmodial activity and favorable toxicity profile we have expanded the chemical diversity of the inhibitors tested as potential antimalarial ...
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The relationship of physico chemical properties and structure to the differential antiplasmodial activity of the cinchona alkaloids
... Partition coefficients between octan-1-ol and water were measured by dual-phase potentiometric titration using various amounts of water-saturated octanol. Titrant addi- tion was carried out with vigorous stirring of the ...
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Antiplasmodial activity of chloroquine analogs against chloroquine resistant parasites, docking studies and mechanisms of drug action
... All were more active against the CQ-R (W2) parasites than against the CQ-S (3D7) parasites, which suggests the ab- sence of cross-CQ-R. In addition, the therapeutic indexes (or SI) of all CQAns, with the exception of ...
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