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Antipsychotic Monotherapy

Remission, response, and relapse rates in patients with acute schizophrenia treated with olanzapine monotherapy or other atypical antipsychotic monotherapy: 12-month prospective observational study

Remission, response, and relapse rates in patients with acute schizophrenia treated with olanzapine monotherapy or other atypical antipsychotic monotherapy: 12-month prospective observational study

... of antipsychotic response, remission, and relapse in patients with schizophrenia treated with olanzapine or other antipsychotics in usual clinical care in ...olanzapine monotherapy (OLZ) and other anti- ...

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Predictors of antipsychotic monotherapy with olanzapine during a 1-year naturalistic study of schizophrenia patients in Japan

Predictors of antipsychotic monotherapy with olanzapine during a 1-year naturalistic study of schizophrenia patients in Japan

... research, antipsychotic polypharmacy was common in the treatment of schizophrenia in ...later antipsychotic monotherapy treatment, including baseline demographics (age, outpatient status), clinical ...

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Antipsychotic monotherapy among outpatients with schizophrenia treated with olanzapine or risperidone in Japan: a health care database analysis

Antipsychotic monotherapy among outpatients with schizophrenia treated with olanzapine or risperidone in Japan: a health care database analysis

... Purpose: Antipsychotic monotherapy is often recommended over antipsychotic polypharmacy because of fewer adverse events, reduced treatment complexity, and lower medication ...of antipsychotic ...

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Antipsychotic monotherapy and polypharmacy in the naturalistic treatment of schizophrenia with atypical antipsychotics

Antipsychotic monotherapy and polypharmacy in the naturalistic treatment of schizophrenia with atypical antipsychotics

... in discerning whether there is a link between treatment effectiveness and antipsychotic monotherapy (or polyp- harmacy). Treatment indication is also important because some antipsychotics, particularly ...

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Controversies in bipolar disorder; role of second-generation antipsychotic for maintenance therapy

Controversies in bipolar disorder; role of second-generation antipsychotic for maintenance therapy

... examined included olanzapine (4 trials), quetiapine (4 trials), aripiprazole (3 trials), risperidone (3 trials) and ziprasidone (1 trial). Meta-analyses showed antipsychotic monotherapy to be superior to ...

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Antipsychotic polypharmacy in a regional health service: a population based study

Antipsychotic polypharmacy in a regional health service: a population based study

... Although antipsychotic polypharmacy is widely used in our healthcare setting, it appears not to follow the avail- able clinical practice guidelines indicating the use of using antipsychotic ...

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Predictors of Discontinuation of  Antipsychotic Therapy in Patients with Acute Schizophrenia: A 1 Year  Observational Study with More Than 1000 Patients

Predictors of Discontinuation of Antipsychotic Therapy in Patients with Acute Schizophrenia: A 1 Year Observational Study with More Than 1000 Patients

... pine antipsychotic monotherapy group, atypical antipsychotics were administered to 487 patients (160 risperi- done, 154 aripiprazole, 44 quetiapine, 67 blonanserin, 40 paliperidone, 16 perospirone, and 6 ...

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The role of antipsychotics and mood stabilizers in the treatment of bipolar disorder

The role of antipsychotics and mood stabilizers in the treatment of bipolar disorder

... atypical antipsychotic treatment trials in bi- polar disorder have confirmed that atypical antipsychotic monotherapy is superior to placebo regarding an acute manic and mixed ...

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Determination of Changes in Blood Biomarker Levels in Antipsychotic Polypharmacy and Aripiprazole Monotherapy in Patients With Long-term Schizophrenia

Determination of Changes in Blood Biomarker Levels in Antipsychotic Polypharmacy and Aripiprazole Monotherapy in Patients With Long-term Schizophrenia

... In this study, there was a negative correlation between BDNF plasma level changes and patient scores in the BPRS test. By increasing the concentration of BDNF, the overall score of the BPRS test was reduced; how- ever, ...

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Antipsychotic and Anticholinergic Drug Prescribing Pattern in Psychiatry: Extent of Evidence Based Practice in Bahrain

Antipsychotic and Anticholinergic Drug Prescribing Pattern in Psychiatry: Extent of Evidence Based Practice in Bahrain

... the antipsychotic prescribing pattern and the prevalence of concurrent anticho- linergic prescribing in a psychiatric referral ...Bahrain. Antipsychotic monotherapy was prescribed for ...mean ...

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Antipsychotic patterns of use in patients with schizophrenia: polypharmacy versus monotherapy

Antipsychotic patterns of use in patients with schizophrenia: polypharmacy versus monotherapy

... total antipsychotic doses, which may increase dose-related side effects, the risk for drug interactions, and complicated dosing regimens that may lead to treatment discontinuation ...of antipsychotic ...

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Reasons and clinical outcomes of antipsychotic treatment switch in outpatients with schizophrenia in real-life clinical settings: the ETOS observational study

Reasons and clinical outcomes of antipsychotic treatment switch in outpatients with schizophrenia in real-life clinical settings: the ETOS observational study

... switching antipsychotic treatment was lack of tolerability (n = 369, ...of antipsychotic monotherapy for reasons relating to lack of efficacy and/or tolerability was associated with significantly ...

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Role of aripiprazole in treatment-resistant schizophrenia

Role of aripiprazole in treatment-resistant schizophrenia

... prior antipsychotic treatments within the previous 5 years at chlorpromazine dosages $ 1000 mg/day for at least 6 weeks without sufficient reduction of positive symptoms or lack of a period of good functioning in ...

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Conformance to schizophrenia treatment guidelines in North West Bank, Palestine: focus on antipsychotic dosing and polytherapy

Conformance to schizophrenia treatment guidelines in North West Bank, Palestine: focus on antipsychotic dosing and polytherapy

... of antipsychotic drug com- bination was significantly higher than those reported in many other ...of antipsychotic polypharmacy while a study in Nigeria reported a prevalence of 92% of anti- psychotic ...

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Approaches to improve adherence to pharmacotherapy in patients with schizophrenia

Approaches to improve adherence to pharmacotherapy in patients with schizophrenia

... In patients with schizophrenia, medication compliance is critical to optimal patient functioning and overall health. Nonadherence to antipsychotic medication regimens is associated with increased risk of ...

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Attempting to discontinue antipsychotic medication: withdrawal methods, relapse and success

Attempting to discontinue antipsychotic medication: withdrawal methods, relapse and success

... Welcome to The Experiences of Antipsychotic Medication Survey. This survey is in 4 parts and usually takes 30 – 45 minutes to complete. Not all questions will be relevant to you, so the time taken to complete the ...

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Antipsychotic Medication and Risk of QTc Prolongation: Focus on Multiple Medication and Role of Cytochrome P450 Isoforms

Antipsychotic Medication and Risk of QTc Prolongation: Focus on Multiple Medication and Role of Cytochrome P450 Isoforms

... pattern, antipsychotic doses and cytochrome P450 (CYP) mediation, us- ing large database describing the antipsychotic treatment of patients with schizophrenia in ...the antipsychotic CPZ-equivalent ...

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Attempting to discontinue antipsychotic medication: withdrawal methods, relapse and success

Attempting to discontinue antipsychotic medication: withdrawal methods, relapse and success

... Antipsychotic medication (AM) is commonly used by people diagnosed with schizophrenia spectrum disorders and bipolar disorder to manage symptoms of psychosis and mania (Castle et al., 2002, Fountoulakis et al., ...

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A Systematic Review on Animal Models of Metabolic
Syndrome

A Systematic Review on Animal Models of Metabolic Syndrome

... Antipsychotic drugs are medications used to treat neuropsychiatric disorders, for examples, schizophrenia, depression, and bipolar disorder. Antipsychotic drugs have been [r] ...

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Atypical antipsychotic drugs and the risk of acute kidney injury: A population-based cohort study

Atypical antipsychotic drugs and the risk of acute kidney injury: A population-based cohort study

... Our study has several strengths. To our knowledge, this is the first population-based study that characterized the risk of AKI associated with atypical antipsychotic drug use. Furthermore, our study explored ...

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