Antisense RNA
Antisense RNA based down-regulation of RNaseE in E.coli
... the antisense mechanism in bacte- ria were based on natural prokaryotic antisense ...that antisense RNA based strategies also can be used to regulate the biosynthesis of global regulatory pro- ...
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<p>LncRNA GA-Binding Protein Transcription Factor Subunit Beta-1 Antisense RNA 1 Inhibits Renal Carcinoma Growth Through an MiR-1246/Phosphoenolpyruvate Carboxykinase 1 Pathway</p>
... noncoding RNA (lncRNA) is a noncoding RNA with more than 200 nucleotides; most have an mRNA-like structure but do not encode ...or RNA to regulate ...ing RNA, p53-induced transcript ...
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HMMR antisense RNA 1, a novel long noncoding RNA, regulates the progression of basal-like breast cancer cells
... lncRNAs, we noticed an lncRNA, HMMR antisense RNA 1 (HMMR-AS1; RP11-80G.1), which is located at 5p34 and is the antisense transcript of hyaluronan-mediated motility receptor (HMMR). In addition, ...
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<p>Long non-coding RNA homeobox A11 antisense RNA (HOXA11-AS) promotes retinoblastoma progression via sponging miR-506-3p</p>
... Homeobox A11 antisense RNA (HOXA11-AS), a highly conserved lncRNA located in the HOXA gene cluster on chromosome 7p15.2, 11 is primordially discov- ered in a mouse embryonic cDNA library. 12 HOXA11-AS has ...
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Inhibition of human immunodeficiency virus type 1 replication in human T cells stably expressing antisense RNA.
... In cell lines with antisense RNA expression detectable by Northern RNA hybridization, human immunodeficiency virus type 1 replication was inhibited to 88% 10 days postinfection and this [r] ...
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Stably expressed antisense RNA to cytomegalovirus UL83 inhibits viral replication.
... an antisense UL83 cDNA. Reverse transcription-PCR detected antisense RNA in the ...4-kb RNA containing coding sequences for pp65 was significantly reduced after infection of antisense ...
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ANTISENSE RNA-MEDIATED INHIBITION OF GMFAD2-1 ENCODING OMEGA-6- DESATURASE
... via antisense RNA expression using the desaturase gene in conjunction with seed specific ...homologous antisense gene was in this case effective to some extent in modifying the fatty acid profile in ...
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An antisense RNA in a lytic cyanophage links psbA to a gene encoding a homing endonuclease
... genes with similarity to the homing endonuclease F-CphI of S-PM2 were located adjacent to the.. intron-containing psbA genes [14] Figure S3.[r] ...
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HIV 1 encoded antisense RNA suppresses viral replication for a prolonged period
... by RNA extraction. The results of antisense strand-specific RT-PCR at R8 region revealed that the majority of HIV-1 asRNAs was enriched in the nuclear fractions in both cell lines, whereas the sense strand ...
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Reduction of rubisco activase levels in tobacco using antisense RNA
... 6.3 Results 6.3.1 Phenotype of the R1 antisense plants 6.3.2 Measurements of CO2 assimilation rate 6.3.3 Relationship between activase content, assimilation rate, Rubisco carbamylation l[r] ...
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RNA silencing and HIV: A hypothesis for the etiology of the severe combined immunodeficiency induced by the virus
... anti-viral RNA silencing defence against the host ...HIV RNA and protein production, dicing up the early transcripts (Figure 3b) or using miRNA/RISC for translational repression (Figure 3c) would prevent ...
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Prognostic value of long noncoding RNAs in gastric cancer: a meta-analysis
... aFaP1 antisense rna 1; anril, cDKn2B antisense rna 1; casc15, cancer susceptibility 15; ccaT2, colon cancer associated transcript 2; gaPlinc, gastric adenocarcinoma associated, positive cD44 ...
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Hypothalamic growth hormone secretagogue receptor regulates growth hormone secretion, feeding, and adiposity
... an antisense RNA for the GHS-R gene under the con- trol of the TH promoter and have reduced levels of GHS-R protein (Figure ...The antisense construct was designed to be specific for the region ...
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Long non-coding RNA and tumor hypoxia: new players ushered toward an old arena
... noncoding RNA Low Expression in Tumor) and HIF1A-AS2 (HIF1A Antisense RNA 2; also known as aHIF) have both been implicated in both negative regu- lation of HIF1A mRNA ...with RNA-binding ...
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Virulence of methicillin-resistant Staphylococcus aureus modulated by the YycFG two-component pathway in a rat model of osteomyelitis
... Objectives: Methicillin-resistant Staphylococcus aureus (MRSA) strains present an urgent medical problem in osteomyelitis cases. Our previous study indicated that the YycFG two-component regulatory pathway is associated ...
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The Research Progress of Long Noncoding RNAs in Nasopharyngeal Carcinoma
... transcript antisense RNA (HOA transcript antisense RNA, HOTAIR) is an elongation of about 2158nt, located in human chromosome 12 on the HOXC site ...transcribed antisense RNA was ...
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Dysregulated long noncoding RNAs(lncRNAs) in hepatocellular carcinoma: implications for tumorigenesis, disease progression, and liver cancer stem cells
... CDKN2B antisense RNA 1; BAF: BRG1-associated factor; BANCR: BRAF-activated noncoding RNA; BCLC: Barcelona Clinic Liver Cancer; CAMTA1: calmodulin binding transcription activator 1; CCAT1: colon ...
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Functional polymorphisms in LncRNA HOTAIR contribute to susceptibility of pancreatic cancer
... Background: Pancreatic cancer (PC) remains one of the most aggressive cancers worldwide. However, genetic fac- tors underlying PC susceptibility remain largely unclear. Long noncoding RNA (lncRNA) HOX transcript ...
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Title: Think Different with RNA Therapy: Can Antisense Oligonucleotides Be Used to Inhibit Replication and Transcription of SARS-CoV-2?
... arsenal, antisense RNA therapy represents an emerging strategy to specifically treat various ...of antisense oligonucleotides (ASOs) targeted to mRNAs, small RNAs or long non-coding ...the RNA ...
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Expression Analysis of BDNF Gene and BDNF-AS Long Noncoding RNA in Whole Blood Samples of Multiple Sclerosis Patients: Not Always a Negative Correlation between Them
... Next, we focused on BDNF antisense RNA (BDNF- AS) which is identified to be a naturally conserved long noncoding RNA (lncRNA). LncRNAs are known as principal regulators of the genome expression and ...
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