Antituberculosis Drugs
Mechanism of hepatoprotective action of methionine and composition “Metovitan” against a background of antituberculosis drugs administration to rats
... of antituberculosis drugs to rats for 60 days in doses that are equivalent to clinical ones, causes changes in mRNA levels expression of liver cytochrome P-450 isoforms CYP3A2 , CYP2C23, CYP2E1 and pro- and ...
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Pharmacokinetics of Antituberculosis Drugs in HIV-Positive and HIV-Negative Adults in Malawi.
... of antituberculosis drugs, particularly rifampin, in HIV- coinfected TB patients (2–11) and the association of these findings with worse treatment outcomes in some studies (11, ...
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Effect of Antituberculosis Drugs on Levels of Serum Proteins in Pulmonary Tuberculosis Patients
... following antituberculosis drugs. All the drugs were given thrice a week through out for 6 months under the direct supervision of clinical ...
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Synergistic Study on n-Hexane Extract of Anredera cordifolia (Ten.)v Steenis (binahong) Leaves Combined with Antituberculosis Drugs against Drug-Sensitive and Drug-Resistant of Mycobacterium tuberculosis
... with antituberculosis drugs against drug sensitive and drug resistant of Mycobacterium tuberculosis ...(TB) drugs was determined by susceptibility test in Lowenstein Jensen (LJ) media by calculating ...
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A Multilaboratory, Multicountry Study To Determine MIC Quality Control Ranges for Phenotypic Drug Susceptibility Testing of Selected First Line Antituberculosis Drugs, Second Line Injectables, Fluoroquinolones, Clofazimine, and Linezolid
... 5 drugs for mul- tidrug-resistant tuberculosis using a 7H9 broth microdilution MIC ...prediluted drugs in 7H9 broth-oleic acid albumin dextrose ...11 drugs: isoniazid ...used antituberculosis ...
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Detection of Resistance to Second Line Antituberculosis Drugs by Use of the Genotype MTBDRsl Assay: a Multicenter Evaluation and Feasibility Study
... We have conducted a multicenter, international study of diag- nostic accuracy across four sites with the aim to assess the perfor- mance of the Genotype MTBDRsl assay in the detection of resis- tance to fluoroquinolones ...
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Economic evaluation of a shortened standardised treatment regimen of antituberculosis drugs for patients with multidrug resistant tuberculosis (STREAM) : study protocol
... Multidrug-resistant tuberculosis (MDR-TB) is a form of tuberculosis resistant to isoniazid (INH) and rifampicin, two of the most important fi rst-line TB drugs. 1 2 The WHO estimates that, globally in 2012, over ...
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NUTREASE POWDER - NATURE’S BLEND OF PROTEIN, FIBER, MULTIVITAMIN, MULTIMINERAL & ANTIOXIDANT SUPPORT IMPROVES THE EFFECTIVENESS OF THE ANTITUBERCULOSIS DRUGS
... Nutritional status is significantly lower in patients with active pulmonary tuberculosis compared with healthy.. controls in different studies in Indonesia, England, India, [r] ...
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Antituberculosis Drugs Resistance and Treatment Outcomes Among Retreatment Patients in Guinea: A Five-Year Retrospective Cohort Study
... To our knowledge, this study is the first in Guinea to describe anti-TB drugs resistance and treatment outcomes among retreatment TB patients. Hence, it showed some major challenges in managing TB including low ...
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Economic evaluation of a shortened standardised treatment regimen of antituberculosis drugs for patients with multidrug-resistant tuberculosis (STREAM): study protocol
... of drugs, laboratory reagents, monitoring stationery, equipment and other consumables will be col- lected from study, health facility or Ministry of Health (MOH) records, according to the procurement ...
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Intracellular delivery of nano formulated antituberculosis drugs enhances bactericidal activity
... of drugs could be a more effective way of killing pathogens (Zhang et ...line drugs, which would allow simultaneous delivery of the drugs in the multidrug treatment ...Targeting drugs to ...
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<p>Resistance To First-Line Antituberculosis Drugs And Prevalence Of <em>pncA</em> Mutations In Clinical Isolates Of <em>Mycobacterium tuberculosis</em> From Zunyi, Guizhou Province Of China</p>
... anti-TB drugs used for both the fi rst- and second-line regimens, which plays an important role in reducing the treatment duration for drug- susceptible and drug-resistant ...
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Diagnostic Accuracy and Reproducibility of WHO Endorsed Phenotypic Drug Susceptibility Testing Methods for First Line and Second Line Antituberculosis Drugs
... anti-TB drugs, around 80% of studies were considered to be at high or unclear risk of bias in patient selection because these studies lacked consecutive or random se- lection of patients or samples, used a ...
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Toward antituberculosis drugs: in silico screening of synthetic compounds against <em>Mycobacterium tuberculosis</em> L,D-transpeptidase 2
... identify a new class of potential antitubercular lead com- pounds. Out of the 4.5 million compounds screened, 18 compounds were found to have better binding energies than meropenem and with satisfactory in silico ADMET ...
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Cure of tuberculosis despite serum concentrations of antituberculosis drugs below published reference ranges
... Sixteen of 17 (94%) patients completed therapy and were cured, based on WHO guidelines definition. Median treat- ment duration among all 17 patients was 317 days (range 23–899 days, table 2). TB treatment of more than 12 ...
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Plasma concentrations of second-line antituberculosis drugs in relation to minimum inhibitory concentrations in multidrug-resistant tuberculosis patients in China: a study protocol of a prospective observational cohort study
... Methods and analysis Adult patients with pulmonary MDR-TB treated in Xiamen, China, are included. Plasma samples for measure of drug exposure are obtained at 0, 1, 2, 4, 6, 8 and 10 hours after drug intake at week 2 and ...
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Gastrointestinal tuberculosis following renal transplantation accompanied with septic shock and acute respiratory distress syndrome: a survival case presentation
... Although treatable and very rare, GITB is a potentially lethal complication after solid organ transplantation. Onset of GITB is most commonly about 2 years after transplantation, however in renal transplant recipients, ...
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Intensified Antituberculosis Therapy in Adults with Tuberculous Meningitis
... of antituberculosis drugs for the current infection; if they were known or suspected to be pregnant; if they had known or suspected hyper- sensitivity to or unacceptable side effects from fluoroquinolones ...
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ROLE OF CYCLODEXTRINS IN NEW ANTIMYCOBACTERIAL FORMULATIONS
... of antituberculosis drugs with lower frequency of administrations, shorter time of treatment, lower doses and fewer side ...such drugs a wide knowledge in phthisiology and tuberculosis drugs ...
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TUBERCULOSIS: A LITERATURE REVIEW
... New antituberculosis drugs molecules have reduced the active tuberculosis treatment regimens for drug- sensitive tuberculosis and more effective treatment for latent bacterial infection tuberculosis & ...
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