Aortic smooth muscle cells
Original Article Hydroxyapatite nanocrystals stimulate osteogenic differentiation in primary human aortic smooth muscle cells by activation of oxidative stress and the ERK pathway
... Increased oxidative stress and reactive oxygen species (ROS) play an important role in the pathogenesis of vascular calcification [10, 11]. Signaling of extracellular signal-regulated kina- ses (ERK) is part of ROS ...
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IL-22 modulates inflammatory properties of human primary aortic smooth muscle cells
... Th22 cells have been found in the vascular wall, the effect of IL-22 on VSMC has not yet been in- ...primary aortic smooth muscle cells ...
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Somite derived cells replace ventral aortic hemangioblasts and provide aortic smooth muscle cells of the trunk
... of smooth muscle cells This origin had been proposed some years ago (Brand-Saberi and Christ, 2000) but has never been demonstrated ...crest cells do not contribute to VSM ...VSM cells ...
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A comparative study of toxicity of TiO<sub>2</sub>, ZnO, and Ag nanoparticles to human aortic smooth-muscle cells
... to cells lining blood vessels have gained extensive research interest, because the contact of human blood vessels with metal-based NPs could be increased for two main ...
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Rat aortic smooth muscle cells in culture express kallikrein, kininogen, and bradykininase activity
... vascular smooth muscle (VSM) cells in culture for the presence of key elements of the glandular kallikrein-kinin ...VSM cells and in ...VSM cells contain ...VSM cells grown in ...
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Interaction of atriopeptin III and vasopressin on calcium kinetics and contraction of aortic smooth muscle cells
... vascular smooth muscle cells (VSMC) was ...vascular smooth muscle cells, perhaps by stimulating particulate guanylate cyclase and ...
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Salvianolic acids: small compounds with multiple mechanisms for cardiovascular protection
... human aortic endothelial cells; NFkB = nuclear factor kappa B; HUVECs = umbilical vein endothelial cells; VE-cadherin = vascular endothelial cadherin; VEGF = vascular endothelial growth factor; ERK = ...
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Abnormality of calmodulin activity in hypertension Evidence of the presence of an activator
... cultured aortic smooth muscle cells from SHR, indicating that the anomaly was not a mere consequence of elevated blood pressure but rather a genetic expression of cells of hypertensive ...
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Actin expression in smooth muscle cells of rat aortic intimal thickening, human atheromatous plaque, and cultured rat aortic media
... of smooth muscle cells of rat and human aortic media shows a predominance of the ...rat aortic intimal thickening, in human atheromatous plaque, and in cultured aortic ...
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Sustained inhibition of intimal thickening In vitro and in vivo effects of polymeric beta cyclodextrin sulfate
... rat aortic smooth muscle cells with an insoluble, sulfated polymer of beta-cyclodextrin (P-CDS) was associated with a dose-dependent inhibition of proliferation induced by fetal calf serum, ...
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An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation
... crest cells, endothelial cells, and ...inhibit smooth muscle differentiation, while the physiological role for Notch in smooth muscle formation during development remains ...
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Isolation and culture of smooth muscle cells from human acute type A aortic dissection
... α-smooth muscle actin is a relatively specific gene of which the expression is relatively restricted to vascular smooth muscle cells ...
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Heat shock protein 27 plays a protective role in thoracic aortic dissection by promoting cell proliferation and inhibiting apoptosis
... Antibodies against HSP27 have been detected in patients with cancer and coronary diseases, although the antibody levels in patients with coronary diseases were not asso- ciated with known coronary risk factors [19]. ...
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miR-27a regulates vascular remodeling by targeting endothelial cells' apoptosis and interaction with vascular smooth muscle cells in aortic dissection
... between endothelial and smooth muscle cells, and the surrounding environment [50-51]. To further understand the mechanisms governing the interactions between EC and VSMC, especially the ones that ...
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The effects of modified low density lipoprotein on coronary artery endothelial and smooth muscle cells
... endothelial cells. The isolation and culture of microvessel endothelial cells from the human heart has not been described previously; they are fastidious cells and difficult to ...endothelial ...
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Bovine endothelial cells in culture produce thromboxane as well as prostacyclin
... Bovine aortic endothelial and smooth muscle cells in culture were incubated with arachidonic acid or prostaglandin ...Although smooth muscle cells produced only ...
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Nicotinamide Phosphoribosyltransferase In Smooth Muscle Cells And Aortic Integrity
... Paraformaldehyde-fixed aortic sections were stained with Picrosirius red using a commercially available kit from Polysciences, Inc (Warrington, PA). Briefly, deparaffinized sections were incubated with 0.1% Sirius ...
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Protective Role for Properdin in Progression of Experimental Murine Atherosclerosis
... of aortic sinus plaques from male and female LDLR 2/2 P KO and LDLR 2/2 P WT mice for smooth muscle cell actin (smooth muscle cells), high resolution imaging and subse- quent ...
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TGF beta 1 and 25 hydroxycholesterol stimulate osteoblast like vascular cells to calcify
... of cells from bovine aortic media that show osteoblastic ...novel cells are primarily distinguished from smooth muscle cells by expression of a surface marker preliminarily ...
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Advanced glycosylation endproducts block the antiproliferative effect of nitric oxide Role in the vascular and renal complications of diabetes mellitus
... chemically inactivate nitric oxide (NO), a potent endothelial cell-derived vasodilator and antiproliferative factor. Since mesenchymal cell proliferation is an early and characteristic lesion of diabetic vasculopathy and ...
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