Apo B
Truncated apo B 70 5–containing lipoproteins bind to megalin but not the LDL receptor
... containing apo B-70.5 (Lp B-70.5) was purified from apo B- 100/apo ...on apo B-100 might not by itself be a functional binding domain and that the apo ...
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ABSENCE OF APO B R3500Q MUTATION AMONG KELANTANESE MALAYS WITH HYPERLIPIDAEMIA
... apolipoprotein B-100 (FDB) is an autosomal dominant genetic disorder associated with hypercholesterolaemia and premature coronary heart ...apolipoprotein B (apo B) gene. Apo B ...
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Lipoproteins containing the truncated apolipoprotein, Apo B 89, are cleared from human plasma more rapidly than Apo B 100 containing lipoproteins in vivo
... apolipoprotein B (apo B-40 and apo B- 89) in a kindred with ...both apo B-40 and apo B-89, but the physiologic mechanisms accounting for the reduced plasma ...
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Two independent lipoprotein receptors on hepatic membranes of dog, swine, and man Apo B,E and apo E receptors
... membranes of 7- to 8-wk-old immature dogs as compared with no detectable LDL binding in the hepatic membranes of adult dogs (greater than 1--1.5 yr of age). Results obtained by in vivo turnover studies of canine 125I-LDL ...
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Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high fat diet
... human apo-B (120 +/- 8 vs 84 +/- 3 mg/dl; P < ...human apo-B levels were due to increased plasma levels of human apo-B48; the human apo-B100 levels did not differ in animals ...
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... and Apo-B levels were the best predictors of adverse cardiovascular outcomes in patients who were on lipid-lowering therapy, and when Apo-B or non-HDL-C was included in the regression model, ...
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A randomized, double blind, placebo controlled, multicenter clinical trial to assess the efficacy and safety of Emblica officinalis extract in patients with dyslipidemia
... Results: In 12 weeks, the major lipids such as total cholesterol (TC) ( p = 0.0003), triglyceride (TG) ( p = 0.0003), low density lipoprotein cholesterol (LDL-C) ( p = 0.0064) and very low density lipoprotein cholesterol ...
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MCP 1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B
... erosclerosis: apo E–deficient mice (9–11) and low-densi- ty lipoprotein (LDL) receptor–deficient mice ...of apo E or the LDL receptor in these mice causes marked retardation of the clearance of lipopro- ...
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Preoperative serum apolipoprotein A-I levels predict long-term survival in non-muscle-invasive bladder cancer patients
... albumin; apo a-i, apolipoprotein a-i; apo B, apolipoprotein B; BMi, body mass index; Cis, carcinoma in situ; Css, cancer-specific survival; GLB, globulin; HDL, high-density ...
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Interaction between free fatty acids and insulin in the acute control of very low density lipoprotein production in humans
... 131I-VLDL apo B versus time ...VLDL apo B production decreased by ...VLDL apo B production did not decrease significantly ...
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Factors influencing atherogenic indices in type 2 diabetic women in northwestern Algeria
... In our female subjects, the TC/HDL ratio was significantly influenced by overall obesity, poor glycaemic control, apo B and LDL levels. According to Stępień et al, in patients with T2D, the TC/HDL ratio is ...
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Phosphatidylcholine and its relation to apolipoproteins A-1 and B changes after Roux-en-Y gastric bypass: a cohort study
... In the groups of patients with diabetes, we observed no changes in ratios involving Apo B and or LDL-cholesterol. This might in part be explained by the large heterogeneity in these groups but can also be ...
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Impaired hepatic apolipoprotein B and E translation in streptozotocin diabetic rats
... of apo B and apo E, and albumin by hepatocytes from diabetic rats was reduced to 37%, 53%, and 23% of ...of apo B and apo E in diabetics is primarily a result of impaired ...
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Prevalence of cardiovascular risk factors in non-menopausal and postmenopausal inpatients with type 2 diabetes mellitus in China
... 2hPG (13.7 ± 4.0 mmol/L), SBP (134.1 ± 18.0 mmHg), DBP (83.2 ± 10.7 mmHg), TC (181.4 ± 38.6 mg/dL), TG (92.6 ± 81.1 mg/dL), HDL-C (42.5 ± 11.6 mg/dL), LDL-C (92.6 ± 30.9 mg/dL), Apo A1 (1.1 ± 0.19 g/L) and ...
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Immune complex hyperlipidemia induced by an apolipoprotein reactive immunoglobulin A paraprotein from a patient with multiple myeloma Characterization of this immunoglobulin
... apolipoprotein B (apo B)- containing lipoproteins that formed macromolecular aggregates, and globules thought to be aggregated complexes of lipoproteins and reactive immunoglobulins were ...
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Effect of saroglitazar 2 mg and 4 mg on glycemic control, lipid profile and cardiovascular disease risk in patients with type 2 diabetes mellitus: a 56-week, randomized, double blind, phase 3 study (PRESS XII study)
... co-variance; Apo A1: Apolipoprotein A1; Apo B: Apolipoprotein B; BP: Blood pressure; CI: Confidence intervals; CVDs: Cardiovascular diseases; CDSCO: Central Drugs Standard Control ...
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Characterization of an abnormal species of apolipoprotein B, apolipoprotein B 37, associated with familial hypobetalipoproteinemia
... individuals apo B-37 was found in very low density lipoproteins, along with the normal apo B species, apo B-100 and apo ...contained apo B-37, but no other ...
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Influence of obesity and cardiometabolic makers on lipoprotein-associated phospholipase A2 (Lp-PLA2) activity in adolescents: the healthy young cross-sectional study
... tendency, where obese adolescents showed higher values in relation to healthy weight adolescents ( P = 0.015). Regarding the apolipoproteins, they were similar between groups, except for Apo AI and Apo ...
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Familial hypobetalipoproteinemia caused by a mutation in the apolipoprotein B gene that results in a truncated species of apolipoprotein B (B 31) A unique mutation that helps to define the portion of the apolipoprotein B molecule required for the formation of buoyant, triglyceride rich lipoproteins
... truncated apo B species, apo B-31. Apolipoprotein B-31 is caused by the deletion of a single nucleotide in the apo B gene, and it is predicted to contain 1425 amino ...
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The relationship of apolipoprotein B and very low density lipoprotein triglyceride with hyperuricemia and gout
... Apolipoprotein B (apo B), amongst other lipoproteins, coats MSU crystals exposed to plasma and, when attached to MSU crystals as part of an entire lipoprotein particle, can suppress the stimulation ...
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