Apolipoprotein CIII
Role of MAPK in apolipoprotein CIII-induced apoptosis in INS-1E cells
... [11,12]. To this aim serum samples from subjects with newly diagnosed diabetes with family history of diabetes (FHD) and impaired β-cell function, and from healthy individuals with no FHD and well functioning β-cells ...
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Association of plasma apolipoprotein CIII, high sensitivity C-reactive protein and tumor necrosis factor-α contributes to the clinical features of coronary heart disease in Li and Han ethnic groups in China
... ApoCIII: Apolipoprotein CIII; CHD: Coronary heart disease; EC: Endothelial cell; EDTA: Ethylene diamine tetra-acetic acid; ELISA: Enzyme-linked immunosorbent assay; FBS: Fasting blood sugar; HDL: High ...
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Familial apolipoprotein AI and apolipoprotein CIII deficiency Subclass distribution, composition, and morphology of lipoproteins in a disorder associated with premature atherosclerosis
... with apolipoprotein AI (apo AI) and apolipoprotein CIII (apo CIII) deficiency were characterized and compared with those of healthy, age- and sex-matched ...
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Apolipoprotein CIII may mediate the impacts of angiopoietin-like protein 8 on triglyceride metabolism
... Liver-derived apolipoprotein CIII (apoCIII), mainly pre- sents on the surface of triglyceride-rich lipoproteins (TRLs) and high-density lipoprotein (HDL) [7], was proved to be a crucial regulator of ...
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Intestinal transcription and synthesis of apolipoprotein AI is regulated by five natural polymorphisms upstream of the apolipoprotein CIII gene
... human apolipoprotein AI (apoAI), relative apoAI synthesis was measured from endoscopic biopsy samples obtained from 18 healthy ...the apolipoprotein CIII gene transcrip- tional start site ( 1 1): ( 2 ...
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Apolipoprotein CIII overexpression exacerbates diet-induced obesity due to adipose tissue higher exogenous lipid uptake and retention and lower lipolysis rates
... Previous studies (reviewed in ref [39]) showed that modulation of LPL activity through its activators [9, 10] or inhibitors [14, 15] may have effects on triglyceride storage. For instance, LPL deficiency in adipose ...
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The effect of longer-term plant sterol and stanol consumption on apolipoprotein CII and apolipoprotein CIII concentrations in humans
... Background: Elevated fasting and postprandial serum levels of triacylglycerol (TAG) are a risk factor for cardiovascular disease (CVD). The dietary components plant sterols and stanols can be used as strategy against ...
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Apolipoprotein B metabolism in subjects with deficiency of apolipoproteins CIII and AI Evidence that apolipoprotein CIII inhibits catabolism of triglyceride rich lipoproteins by lipoprotein lipase in vivo
... apo CIII-apo-AI deficient patients were able to normally activate purified LPL, increasing volumes of these sera did not result in the progressive inhibition of LPL activity demonstrable with normal ...apo ...
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Chylomicronemia due to apolipoprotein CIII overexpression in apolipoprotein E null mice Apolipoprotein CIII induced hypertriglyceridemia is not mediated by effects on apolipoprotein E
... proposed lipase inhibitor (apoE) would be absent, versus the HuCIII Tg argues against an antilipolytic effect of apoE but does not, by itself, rule out such a role. It does indicate that, in our model, the direct effects ...
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Association of the S2 allele of the SstI polymorphism in the apoC3 gene with plasma apoCIII interacts with unfavorable lipid profiles to contribute to atherosclerosis in the Li ethnic group in China
... ApoCIII: Apolipoprotein CIII; BMI: Body mass index; CHD: Coronary heart disease; DNA: Deoxyribonucleic acid; EDTA: Ethylene diamine tetra-acetic acid; ELISA: Enzyme-linked immunosorbent assay; FBS: Fasting ...
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Hypertriglyceridemia: a too long unfairly neglected major cardiovascular risk factor
... the apolipoprotein CIII (apo CIII) concentration medi- ated transcriptionally by peroxisome proliferator activated receptor (PPAR) ...in apolipoprotein CIII reduces the inhibition of ...
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ApoA-I/A-II-HDL positively associates with apoB-lipoproteins as a potential atherogenic indicator
... HDL apolipoprotein markers including those for its subfractions, total apoA- I, apoA-I in LpAI and LpAI:AII and apoA-II, to apoB, an apolipoprotein parameter to indicate particle number of LDL and very low ...
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LXR agonist increases apoE secretion from HepG2 spheroid, together with an increased production of VLDL and apoE-rich large HDL
... apoA-I: apolipoprotein A-I; apoB: apolipoprotein B; apoE: apolipoprotein E; TO: TO901317; M-Hep: HepG2 cells cultured in monolayer; S-Hep: HepG2 cells cultured in spheroidal form; HNF: h[r] ...
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Behavior of CIII to CVI Emissions during the Recombining Phase of LHD Plasmas
... charge is initiated by electron cyclotron heating (ECH) and the plasma is sustained by three negative-ion-based neu- tral beam injection (NBI) devices. Several spectroscopic diagnostics covering visible to X-ray ...
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Structural relationship of human apolipoprotein B48 to apolipoprotein B100
... Although the complete amino acid sequence of human apolipoprotein (apo) B100 is known (4536 amino acids), the structure of apo B48 has not been defined. The objective of our study was to define the structure of ...
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pH-responsive high-density lipoprotein-like nanoparticles to release paclitaxel at acidic pH in cancer chemotherapy
... 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC, Avanti Polar Lipids, Alabaster, AL) was prepared as a 25 mM stock solution in chloroform, and was dried under a stream of nitrogen gas to produce a lipid film on ...
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Serum apolipoprotein C3 levels are negatively associated with hepatitis B virus DNA in HBeAg-negative chronic hepatitis B patients
... of apolipoprotein A1 (ApoA1) and apolipoprotein B (ApoB) were examined using immunoturbidimetric method, and the serum levels of high-density lipoproteins cholesterol (HDL-C), low-density lipoproteins ...
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Apolipoprotein L1 Variant Associated with Increased Susceptibility to Trypanosome Infection
... ABSTRACT African trypanosomes, except Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense, which cause human African trypanosomiasis, are lysed by the human serum protein apolipoprotein L1 (ApoL1). ...
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Apolipoprotein M
... Apolipoprotein M (apoM) is a 26-kDa protein that is mainly associated with high-density lipoprotein (HDL) in human plasma, with a small proportion present in triglyceride-rich lipoproteins (TGRLP) and low-density ...
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Physiological serum total bilirubin concentrations were inversely associated with diabetic peripheral neuropathy in Chinese patients with type 2 diabetes: a cross-sectional study
... (LDL-C), apolipoprotein A (apoA), apolipoprotein B (apoB), and creatinine (Crea) were analyzed enzymatically using a 7060 full-automatic biochemical analyzer (Hitachi, Tokyo, Japan) at a certified ...
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