Apoptosis and human disease
Regulation of apoptosis at the point of cytochrome c in disease models
... c. Apoptosis in chronic neurodegenerative diseases The role of apoptosis remains controversial in various neurodegenerative diseases, as it is difficult to detect apoptotic cells in chronic pathological ...
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on proliferation and apoptosis of human HepG2 cells
... mediating apoptosis in tumor formation, such as nuclear factor-κB (NF- κB), caspase3, activating protein-1 (AP-1), sig- nal transducer and activator of transcription (STAT) ...liver disease, and hepatitis B ...
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Oxidative Stress, a-Synuclein, and Apoptosis in Parkinson’s Disease
... Several molecular species and drugs are thought to lead to the onset of PD and have been used to successfully produce Parkinsonism in model organisms. Dopamine, itself, is thought to be the single most important species ...
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Leflunomide inhibits the apoptosis of human embryonic lung fibroblasts infected by human cytomegalovirus
... viruses. Human cytomegalovirus (HCMV) belongs to the β sub- family of the herpes virus, and is the most common pathogen of utero and postnatal infection, which can cause stillbirth, fetal malformation, ...
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Human Lymphocyte Apoptosis after Exposure to Influenza A Virus
... of apoptosis of lymphocytes by the ...soluble human Fas, Ac-DEVD-CHO (caspase-3 inhibitor), or Z-VAD-FMK (general caspase inhibitor), apoptosis and production of the active form of caspase-3 was ...
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Hyperglycaemia and apoptosis of microglial cells in human septic shock
... vascular disease, and severity of illness using simplified acute physiology score II (SAPS II) [17] and sequential organ failure assessment (SOFA) [17,18] score were rou- tinely ...
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Hyperglycaemia and apoptosis of microglial cells in human septic shock
... vascular disease, and severity of illness using simplified acute physiology score II (SAPS II) [17] and sequential organ failure assessment (SOFA) [17,18] score were rou- tinely ...
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Effects of chemokines on proliferation and apoptosis of human mesangial cells
... adult human kidney and regulation of glomerular cell numbers during disease ...in human renal ...MC apoptosis cell death was induced by activat- ing mesangial Fas/CD95 ...MC apoptosis ...
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Theophylline accelerates human granulocyte apoptosis not via phosphodiesterase inhibition
... The regulation of granulocyte apoptosis has been proposed as a key mechanism for the inhibition of inflammatory disease and tissue damage. Theophylline, a methylxanthine derivative and nonspecific ...
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Amitriptyline induces mitophagy that precedes apoptosis in human HepG2 cells
... 39. Kurz T, Terman A, Gustafsson B and Brunk UT. Lysosomes in iron metabolism, ageing and apoptosis. Histochemistry and cell biology. 2008; 129(4):389-406. 40. Wirawan E, Vande Walle L, Kersse K, Cornelis S, ...
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Silencing of hepcidin enforces the apoptosis in iron-induced human cardiomyocytes
... Cardiomyocyte apoptosis can result in a loss of con- tractile tissue, compensatory hypertrophy of myocardial cells, reparative fibrosis, and heart ...kidney disease (CKD) patients [26] demonstrated that ...
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Apoptosis signal regulating kinase 1 inhibition attenuates human airway smooth muscle growth and migration in chronic obstructive pulmonary disease
... DISCUSSION There have been several studies investigating the role of ASK1 in cytokine production, apoptosis and inflammation but very few have focused on its role in cell growth and/or proliferation (25). In the ...
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Apoptosis in ischemic heart disease
... Low TRAIL levels can predict worse prognosis also in patients with chronic heart failure and in older patients with cardiovascular disease [25, 51]. In conclusion, serum TRAIL levels seem to represent an important ...
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Parkinson’s Disease—Apoptosis and Dopamine Oxidation
... Received March 2, 2012; revised April 3, 2012; accepted April 13, 2012 ABSTRACT Tyrosine hydroxylase, monoamine oxidase and aldehyde dehydrogenase all form oxygen radicals as part of their mechanisms of action. These ...
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Activation of Human Herpesvirus Replication by Apoptosis
... or human herpesvirus-8 [HHV-8]) has another, alternative emergency escape replication pathway that is triggered when KSHV’s host cell undergoes apoptosis, characterized by the lack of a requirement for the ...
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Activation of human herpesvirus replication by apoptosis
... or human herpesvirus-8 [HHV-8]) has another, alternative emergency escape replication pathway that is triggered when KSHV’s host cell undergoes apoptosis, characterized by the lack of a requirement for the ...
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The effects of dexmedetomidine on human neutrophil apoptosis
... on human neutrophil apoptosis and superoxide production in ...ng/mL). Apoptosis was assessed by Hoechst 33342 staining, caspase activities and loss of mitochondrial transmembrane potential ...
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Human Cytomegalovirus UL38 Protein Blocks Apoptosis
... 2006 Apoptosis is an innate cellular defense response to viral ...slow-replicating human cytomega- lovirus (HCMV) blocks premature death of host cells prior to completion of the infection ...in human ...
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Nanoparticles of barium induce apoptosis in human phagocytes
... induce apoptosis and/or necrosis due to changes in intracel- lular calcium homeostasis and promotion of microvascular endothelial ...higher apoptosis rate but lower number of necrotic ...
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Induction of T-cell apoptosis by human herpesvirus 6.
... First, apoptosis was detected morphologically in small cells and not in virus-producing large syncytial cells, and virus struc- tures were hardly detected in apoptotic cells by electron mi- ...that ...
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