Apoptosis-inducing factor (AIF)
Role of Apoptosis Inducing Factor (AIF) as Risk Factors of Premature Rupture of Membranes
... and apoptosis, and the stretch of the amniotic membrane. Apoptosis plays an integrated role in the pathogenesis of ...of apoptosis is through caspase-dependent and caspase-independent ...pathway. ...
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Apoptosis inducing factor (AIF) mediates lethal redox stress induced by menadione
... Mitochondrial apoptosis inducing factor (AIF) is a redox-active enzyme that participates to the biogenesis/maintenance of complex I of the respiratory chain, yet also contributes to catabolic ...
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CHROMONE-3-ALDEHYDE DERIVATIVES IMPROVE MUSCLE FUNCTION BY SUPPRESSING THE FORMATION OF APOPTOSIS-INDUCING FACTOR
... To conduct a series of biochemical tests produced the preliminary preparation of the biomaterial: the citrate blood was centrifuged with obtaining a serum in the regime of 3500 RPM for 15 min. the Muscle tissue is ...
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CD317 Promotes the survival of cancer cells through apoptosis-inducing factor
... in AIF release and accumulation in nucleus Many studies have shown that cells usually suffered mito- chondria dysfunction during serum deprivation, exerting low mitochondrial membrane potential (MMP, ΔΨm) and high ...
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Ginsenoside compound K induces apoptosis in nasopharyngeal carcinoma cells via activation of apoptosis-inducing factor
... HK-1 cells were seeded on a glass coverslip at a density of 2 × 10 5 cells/well in a 6-well plate and incubated over- night. Cells were starved with 1% FBS medium for 24 h and then treated with or without CK for another ...
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The role of HGF-MET pathway and CCDC66 cirRNA expression in EGFR resistance and epithelial-to-mesenchymal transition of lung adenocarcinoma cells
... AIF: Apoptosis-inducing factor; ATAD3A: ATPase family, AAA domain-containing 3A; ATM: Ataxia-telangiectasia-mutated kinase; CCDC66: Coiled-coil domain containing 66; CIP: Calf intestinal ...
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AIF Downregulation and Its Interaction with STK3 in Renal Cell Carcinoma
... Apoptosis-inducing factor (AIF) was initially identified as a death effector involved in caspase-independent apoptosis pathway ...length AIF is synthesized in cytoplasm as a ...
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The role of death-associated protein 3 in apoptosis, anoikis and human cancer
... death; AIF: Apoptosis inducing factor; AKT/PKB: Protein kinase B; APAF1: Apoptotic protease activating factor 1; BAX: BCL2 associated X protein; BCL2: B-cell lymphoma 2 protein; BID: ...
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Brain selective kinase (BRSK) interactions with tau as a cause of neurodegeneration
... Abbreviations and acronyms AA: Amino acid Aβ: β amyloid Ach: Acetylcholine AD: Alzheimer’s disease AIF: Apoptosis-inducing factor AMP: Adenosine monophosphate Arpc2: Actin-related protei[r] ...
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Endonuclease G takes part in AIF-mediated caspase-independent apoptosis in Mycobacterium bovis-infected bovine macrophages
... caspase‑independent apoptosis in bovine macrophages with the possible participation of apoptosis inducing factor mitochondria associated 1 (AIFM1/AIF), a flavoprotein that functions as ...
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Heat shock pretreatment improves mesenchymal stem cell viability by heat shock proteins and autophagy to prevent cisplatin-induced granulosa cell apoptosis
... the apoptosis of Sca-1+ stem cells and myocardial fibrosis and the improvement of car- diac ...decreased apoptosis of HS-MSCs, which was con- sistent with the result of a previous study ...
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Distinct intracellular signaling in Tumor Necrosis Factor-related Apoptosis-inducing Ligand- and CD95 Ligand-mediated apoptosis
... to apoptosis after TRAIL or CD95L exposure is the presence of CD95 and all four TRAIL receptors on the target ...CD95L-induced Apoptosis in CC531s Cells—To study the effect of TRAIL and CD95L signaling, we ...
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Apoptosis-inducing and apoptosis-preventing functions of poliovirus.
... of apoptosis are the nucleolytic internucleosomal degra- dation of chromosomal DNA because of the activation of a Ca 21 -dependent nuclease, compaction and fragmentation of chromatin, and cellular shrinkage, as ...
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Reconstruction of gene regulatory networks reveals chromatin remodelers and key transcription factors in tumorigenesis
... necrosis factor-related apoptosis-inducing ligand) sensitivity [16] (Additional file 2: Figure S2), we assessed the global gene expression in all three cell lines and the ratio of expression levels ...
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TRAIL gene 1595C/T polymorphisms contribute to the susceptibility and severity of intervertebral disc degeneration: a data synthesis
... We conducted a computer-based retrieval using the fol- lowing English and Chinese databases: PubMed, Embase, the China National Knowledge Infrastructure database, and the China Biology Medical Literature database. We did ...
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Surface modification of TPGS b (PCL ran PGA) nanoparticles with polyethyleneimine as a co delivery system of TRAIL and endostatin for cervical cancer gene therapy
... necrosis factor-related apoptosis- inducing ligand (TRAIL) is a type 2 transmembrane pro- tein that causes apoptosis of target cells through the extrinsic apoptosis ...necrosis ...
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Kemter, Elisabeth (2005): Untersuchung transgener Tiermodelle für die Xenotransplantation. Dissertation, LMU München: Tierärztliche Fakultät
... Bei dem Caspase-abhängigen intrazellulären Signalweg, induziert durch TRAIL/TRAIL-Rezeptor- Interaktion, erfolgt über die Rekrutierung von zytoplasmatischen Proteinen an die Todesdomäne der Rezeptoren die Bildung des ...
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Original Article Combined strategies of tumor necrosis factor-related apoptosis-inducing ligand and small molecular drugs to inhibit pancreatic cancer cell proliferation and tumor growth
... and inhibition of NF-κB has been suggested to be an important mechanism for this [24, 25]. Previous studies showed that resveratrol also inhibits XIAP expression [26]. Therefore, resve- ratrol plus TRAIL for treatment of ...
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Combination of isoliquiritigenin and tumor necrosis factor-related apoptosis-inducing ligand induces apoptosis in colon cancer HT29 cells
... causes apoptosis by interacting with specific pro-apoptotic receptors, DR5 and ...induces apoptosis through TRAIL receptors, we used a DR5/Fc chimeric protein which has a dominant negative effect, because ...
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Vascular endothelial growth factor (VEGF) upregulates BCL 2 and inhibits apoptosis in human and murine mammary adenocarcinoma cells
... survival factor. However, we demonstrate that VEGF is a survival factor for both murine 4T1 and human MDA-MB-231 tumour cells, preventing tumour cell ...cell apoptosis is further supported by recent ...
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