Apoptotic cells
Phosphatidylserine dependent ingestion of apoptotic cells promotes TGF β1 secretion and the resolution of inflammation
... of apoptotic cells, by selective induction of TGF- β , appears to tip the balance toward an active anti-inflammatory state and, thereby, may pro- mote resolution of ...intact apoptotic cells ...
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MFG E8–mediated uptake of apoptotic cells by APCs links the pro and antiinflammatory activities of GM CSF
... Th1 cells, compromises tolerance and evokes the development of autoantibodies and immune complex mediated ...Th17 cells, with widespread acute and chronic granulomatous inflammation that resembles the ...
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C-reactive protein does not opsonize early apoptotic human neutrophils, but binds only membrane-permeable late apoptotic cells and has no effect on their phagocytosis by macrophages
... late apoptotic cells may have been gated out as "debris" when analysed by flow ...these cells pellet poorly in cytocentrifuge preparations, and this combined with their "invisibility" ...
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Tranilast enhances the anti-tumor effects of tamoxifen on human breast cancer cells in vitro
... displayed apoptotic cells in MCF-7 and MDA-MB-231 cells treated with TAM and tranilast alone or a combination two compared to untreated control ...of apoptotic cells were quantitated ...
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The role of dendritic cells in the pathogenesis of systemic lupus erythematosus
... of apoptotic cells ...of apoptotic cells, combined with a SLE-susceptible genetic background, high (local or systemic) concentrations of apoptotic nucleosomes and blebs are present in ...
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Original Article Dynamaic changes of proliferation and apoptosis in rat retina development
... nerve cells has a unique bio- logical significance in the development of reti- ...of apoptotic cells in retina development at E14, E20, P1, P3, P5, P7, P9, P15 and P36, ...development, ...
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Apoptosis-induced anticancer effect of transferrin-conjugated solid lipid nanoparticles of curcumin
... Tf-C-SLN-treated cells showed >3- and ...Tf-C-SLN-treated cells while in CSSS-treated cells the ROS generation became almost stag- nant after 12 h substantiating the results of cell ...
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A paradox of immunodeficiency and inflammation in human aging: lessons learned from apoptosis
... dead cells is of vital importance in developing and maintaining the normal tissue homeostasis and resolution of ...of apoptotic cells without inflamma- tion or ...of apoptotic cells by ...
8
Anti-tumor effects of a recombinant anti-prostate specific membrane antigen immunotoxin against prostate cancer cells
... in cells expressing immunocasp-3 by the electronic microscope, including chromatin condensation and mar- gination at the nuclear periphery, cellular shrinkage and blebbing, and formation of apoptotic bodies ...
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Original Article rhEPO affects apoptosis in hippocampus of aging rats by upregulating SIRT1
... of apoptotic cells in the central nervous ...progenitor cells increase signifi- cantly and their normal distribution is disrupt- ...cell apoptotic pathway is an impor- tant downstream channel ...
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Pro-apoptotic versus anti-apoptotic properties of dietary resveratrol on tumoral and normal cardiac cells
... dead cells were found at 48 and 72 h in comparison with untreated cells (5–15%) ...HL1-NB cells associated with a loss of cell adhesion was observed (data not ...an apoptotic process revealed ...
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Evaluation of Apoptosis Inducing Ability of Parkia javanica Seed Extract in Cancer Cells
... h, cells were harvested and the cell suspension was adjusted to a concentration to 1 00 000 ...harvested cells were washed with PBS and suspended in 100 µl binding buffer ...(1X). Cells were ...
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Avian Influenza Virus A/HK/483/97(H5N1) NS1 Protein Induces Apoptosis in Human Airway Epithelial Cells
... NS1-expressing cells. To delineate the apoptotic pathway, we first measured the cleavage of caspase-activated PARP at 6, 12, 18, 24, and 30 h posttransfection using Western blot ...NS1-expressing ...
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Atrophy of primary lymphoid organs induced by Marek’s disease virus during early infection is associated with increased apoptosis, inhibition of cell proliferation and a severe B-lymphopenia
... in cells of the medulla of the thymus and of bursa follicles in suscepti- ble newly-hatched birds infected with HPRS-16 from 4 to 6 dpi ...the cells were pp38 positive, indicating that death of infected ...
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Milk Fat Globule-EGF Factor VIII in Sepsis and Ischemia-Reperfusion Injury
... gulfment of apoptotic cells by phagocytes. Phagocytosis prevents the release of po- tentially harmful or immunogenic materi- als from dying cells. We have shown that MFG-E8 expressions are ...
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Nitric oxide-associated chondrocyte apoptosis in trauma patients after high-energy lower extremity intra-articular fractures
... Finally, our study found persistent co-staining of NO and apoptosis with increasing time from injury as a nega- tive correlation, which is supported by the literature. Lima et al. [26] found chondrocyte death increased ...
7
Is disturbed clearance of apoptotic keratinocytes responsible for UVB induced inflammatory skin lesions in systemic lupus erythematosus?
... of apoptotic cells in SLE ...of apoptotic cells ...totic cells is normal when mice are not in a state of active dis- ease ...the apoptotic cell clearance rate in patients with ...
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FETUIN A IN PATIENTS WITH KIDNEY DISEASE
... in apoptotic vascular smooth muscle cells [25] and apoptotic cells have been demonstrated in tubular cells in cisplatin-or ischemia and reperfusion (I/R)- induced acute kidney injury ...
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Apoptotic response of malignant rhabdoid tumor cells
... the apoptotic outcome in MON cells can be triggered by treatments combining the PI3-K inhibitor wortmannin with another ...protecting cells from apoptosis by inhibiting BAD and thus cytochrome C ...
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Translational developments in the study of sepsis: investigations into molecular pathways, experimental modelling and applications of novel biomarkers
... 264.7 cells dosed with LPS The nuclear extract of the RAW 264.7 cells dosed with LPS was collected after 1 hour to quantify (with densitometry) the translocation of p65 from the cytoplasm to the nucleus ...
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