Arachidonic acid (AA)
Cytochrome P450 metabolites of arachidonic acid are potent inhibitors of vasopressin action on rabbit cortical collecting duct
... Cytochrome P450 metabolites of arachidonic acid are potent inhibitors of vasopressin action on rabbit cortical collecting duct.. AA is metabolized by a cytochrome P450, NADPH-dependent e[r] ...
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Individual variation and intraclass correlation in arachidonic acid and eicosapentaenoic acid in chicken muscle
... of AA with enhancement of the intake of oleic acid will, moreover, also be a better strategy for reducing the total extent of in vivo lipid peroxidation, rather than adding more EPA (with 5 double bonds) ...
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Increasing dietary linoleic acid does not increase tissue arachidonic acid content in adults consuming Western-type diets: a systematic review
... of AA no longer respond to dietary LA intakes above 2% energy in adults ...alpha-linolenic acid (ALA, 18:3 n-3) are 12 g-17 g/d and ...ALA, AA, and long-chain n-3 PUFAs, i.e. eicosapentae- noic ...
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Dietary n 3 fatty acid effects on neutrophil lipid composition and mediator production Influence of duration and dosage
... neutrophil lipids; the arachidonic acid (AA) to EPA ratio in neutrophil phospholipids showed a maximal reduction of 49:1 to 8:1 within 1 wk of beginning supplementation. EPA was preferentially ...
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Decreased circulating dihomo-gamma-linolenic acid levels are associated with total mortality in patients with acute cardiovascular disease and acute decompensated heart failure
... [eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)] have the first double bond at the third carbon from the methyl terminus, and omega-6 PUFAs [arachidonic acid (AA) and ...
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Dietary supplementation of α-linolenic acid induced conversion of n-3 LCPUFAs and reduced prostate cancer growth in a mouse model
... Arachidonic acid (AA; 20:4, n-6) is the predominant product of the n-6 pathway and is usually a precursor for the synthesis of eicosanoids, which are involved in pro-inflammatory effects ...the ...
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Interferon gamma induces the synthesis and activation of cytosolic phospholipase A2
... Both IFN-alpha/beta and IFN-gamma have recently been demonstrated to induce a rapid but transient activation of phospholipase A2 (PLA2) in BALB/c 3T3 fibroblasts and a human neuroblastoma cell line. We report that ...
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Pharmacokinetics and pharmacodynamics of nitroglycerin and aspirin
... AA arachidonic acid ASA acetylsalicylic acid, aspirin AUC area under the plasma concentration-time curve GA gentisic acid GC gas chromatography GC-MS gas chromatography - mass spectromet[r] ...
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Role of dietary fatty acids in mammary gland development and breast cancer
... Linoleic acid (LA, 18:2n6) (see Figure 1d) and arachidonic acid (AA, 20:4n6) are the two most common n-6 PUFA in typical western diets [16,17] and have been suggested to have cancer-promoting ...
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Dietary intakes and food sources of omega 6 and omega 3 polyunsaturated fatty acids in pregnant women living in New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Masters of Science in Human Nutrition at Massey University, Albany, New Zealand
... (linoleic acid, LA; alpha linolenic acid, ALA; arachidonic acid, AA; eicosapentaenoic acid, EPA; docosahexaenoic acid, DHA) were compared with dietary recommendations ...
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Relationship between central and peripheral fatty acids in humans
... fatty acid levels were asso- ciated with the CSF omega-3 PUFA ’s, DPA and ...subfraction AA was also ...C]- arachidonic acid can be visualized, after only 15 minutes, in human cranial images ...
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Investigation of cyclooxygenase and signaling pathways involved in human platelet aggregation mediated by synergistic interaction of various agonists
... as arachidonic acid (AA) when combined with 5-hydroxytryptamine (5-HT) or adenosine diphosphate (ADP) on human platelet aggregation were ...and AA exhibited noticeable rise in platelet ...of ...
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Prostaglandin E2 receptors in asthma and in chronic rhinosinusitis/nasal polyps with and without aspirin hypersensitivity
... AA: Arachidonic acid; AERD: Aspirin exacerbated respiratory disease; AT: Aspirin- tolerant; cAMP: Cyclic adenosine monophosphate; COX: Cyclooxygenase; CRS: Chronic rhinosinusitis; CRSwNP: Chronic ...
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Prostaglandin D2 supplemented “functional eicosanoid testing and typing” assay with peripheral blood leukocytes as a new tool in the diagnosis of systemic mast cell activation disease: an explorative diagnostic study
... ripheral blood leukocytes (PBLs) in vitro upon exposure to arachidonic acid (AA), acetylsalicylic acid (ASA), or sub- stance P (SP). The measured eicosanoid levels are then processed by ...
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Fatty Acids and Autism Spectrum Disorders: The Rett Syndrome Conundrum
... To this regard, a quite enigmatic feature of the disease is the evidence in the affected patients of an extensive peroxidation of polyunsaturated fatty acids arachidonic acid, AA, docosa[r] ...
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Epithelium-specific Ets transcription factor-1 acts as a negative regulator of cyclooxygenase-2 in human rheumatoid arthritis synovial fibroblasts
... AA: arachidonic acid; AP‑1: activator protein 1; BMDM: bone marrow‑derived macrophage; C4HSU: control helper‑dependent adenoviral vector; cDNA: complementary deoxyribonucleic acid; C/EBP: CAAT ...
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... linoleic acid (LA), arachidonic acid (AA), alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) were measured using ...
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Protective Effect of Polyunsaturated Fatty Acids Against Experimental Lung Injury Induced by Acute Ethanol Inhalation
... fatty acid ethyl esters (FAEEs, non-oxidative metabolites of ...membrane arachidonic acid (AA), linolenic acid (LA), and oleic acid (OA) along with a significant decrease in ...
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Key words
... GLA, AA, EPA, and DHA may Table 2. Effect of linoleic acid (LA), α-linolenic acid (ALA), arachidonic acid (AA), eicosapentaenoic acid (EPA), and docosahexaenoic ...
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FADS1-FADS2 genetic polymorphisms are associated with fatty acid metabolism through changes in DNA methylation and gene expression
... linoleic acid, (B) a-linolenic acid (C) gamma-linolenic acid, (D) dihomo-gamma-linolenic acid, (E) arachidonic acid, (F) eicosapentaenoic acid, (G) adrenic acid, ...
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