Arc directly interacts with the AP-2 complex
Apm4, the mu subunit of yeast AP-2 interacts with Pkc1, and mutation of the Pkc1 consensus phosphorylation site Thr176 inhibits AP-2 recruitment to endocytic sites.
... To link to this article: http://dx.doi.org/10.4161/cib.28522 PLEASE SCROLL DOWN FOR ARTICLE Taylor & Francis makes every effort to ensure the accuracy of all the information (the “Content”) contained in the publications ...
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hSSB1 interacts directly with the MRN complex stimulating its recruitment to DNA double strand breaks and its endo nuclease activity
... MRN complex to sites of DSBs and for the efficient initiation of ATM dependent ...binds directly to NBS1, a compo- nent of the MRN complex, in a DNA damage independent ...MRN complex, a ...
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HNE interacts directly with JNK isoforms in human hepatic stellate cells
... HNE has been shown to stimulate procollagen type I gene expression and synthesis in human hepatic stellate cells (hHSC) which are known to play a key role in liver fibrosis. In this study we investigated the molecular ...
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A human microprotein that interacts with the mRNA decapping complex.
... decapping complex in cell lysates depleted of individual candidate interaction partners ...Nobody interacts with the decapping complex via direct interactions with EDC4, though does not completely ...
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Pestivirus Npro Directly Interacts with Interferon Regulatory Factor 3 Monomer and Dimer
... IRF3 directly without any other protein and whether the monomeric or dimeric form of IRF3 or both forms interact with N pro ...pro interacts with IRF3 directly without additional proteins and forms a ...
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The Rotavirus Enterotoxin NSP4 Directly Interacts with the Caveolar Structural Protein Caveolin-1
... Although further analyses are needed to distinguish the com- position of these bands, these data confirm the interaction of NSP4–caveolin-1 during RV infection of mammalian cells. NSP4 113-149 and NSP4 114-135 peptides ...
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CaMKIIδ interacts directly with IKKβ and modulates NF-kB signalling in adult cardiac fibroblasts
... H 2 O 2 ...H 2 O 2 may cause aggregation of CaMKII through formation of disulphide and non-disulphide bridges so there is the possibility that the presence of dimers could affect the PLA ...
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Characterization of the adaptor-related protein complex, AP-3.
... the AP-3 complex is associated with the Golgi region of the cell as well as with more periph- eral ...the AP-3 complex may be directly involved in trafficking to lysosomes or ...
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Adenovirus E1A Directly Targets the E2F/DP-1 Complex
... E1A directly associates with E2F/DP-1 complexes, likely through binding to ...to directly influence E2F-responsive genes without relying only on the deregulation of the pRb family of ...
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PIH1D1 interacts with mTOR complex 1 and enhances ribosome RNA transcription
... a b s t r a c t PIH1D1 is the defining component of the R2TP complex. Recently, R2TP has been reported to stabi- lize mTOR (mammalian target of rapamycin), an important regulator of cell growth and protein syn- ...
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The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy
... Whitworth 2 , † , Brian K Kaspar 3 , Kathrin Meyer 3 , Pamela J Shaw 1 , Andrew J Grierson 1 ,§ & Kurt J De Vos 1 ,§,* Abstract A GGGGCC hexanucleotide repeat expansion in the C9orf72 gene is the most common ...
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Borna Disease Virus Nucleoprotein Interacts with the Cdc2-Cyclin B1 Complex
... the BDV nucleoprotein and the Cdc2-cyclin B1 complex of the host cell. As a consequence, Cdc2 appears to be kept in an inactive state, resulting in a delay in G 2 phase progression. The effects appear to be ...
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cGMP interacts with tropomyosin and downregulates actin-tropomyosin-myosin complex interaction
... However, besides these downstream-regulated genes, lit- tle is known about the interaction proteins of cGMP. As a second messenger in cells, cGMP hardly acts as isolated species while performing its functions in vivo. In ...
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The Chediak-Higashi Protein Interacts with SNARE Complex and Signal Transduction Proteins
... Ca 2 -binding ...Ca 2 -binding site and an ...Ca 2 -dependent ...Ca 2 release, causing CALM to bind tightly to the docked vesicle and promote membrane ...Ca 2 in- hibits interaction of ...
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Flavivirus sfRNA suppresses antiviral RNA interference in cultured cells and mosquitoes and directly interacts with the RNAi machinery
... In order to assess the in fluence of KUNV sfRNA expression on the ef ficiency of RNAi activity in infected mosquitoes, dsRNA Fig. 2. siRNA-mediated mRNA knockdown is inhibited in KUNV infections in an ...
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Trithorax monomethylates histone H3K4 and interacts directly with CBP to promote H3K27 acetylation and antagonize Polycomb silencing
... TRR complex suggests that TRR can facilitate switching of PcG-regulated genes from silent to active, whereas TRX might only be capable of maintaining the expression of genes activated prior to the onset of ...
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Vascular endothelial growth factor receptor-3 directly interacts with phosphatidylinositol 3-kinase to regulate lymphangiogenesis
... P70S6K, eNOS and PLCc, but not mTOR, are Activated by VEGF-C Signaling through VEGFR-3 To identify the pathways downstream of Akt activation in response to VEGF-C, we examined the effects of VEGFR ligands on the ...
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PHYSICAL MODELLING OF TERRAIN DIRECTLY FROM SURFER GRID AND ARC/INFO ASCII DATA FORMATS #1
... [email protected] ABSTRACT Additive manufacturing technology is used to make physical models of terrain using GIS surface data. Attempts have been made to understand several other GIS file formats, such as the Surfer ...
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Human Herpesvirus 8 Viral Interleukin-6 Interacts with Splice Variant 2 of Vitamin K Epoxide Reductase Complex Subunit 1
... Reductase Complex Subunit 1 Daming Chen, Emily Cousins, Gordon Sandford, and John Nicholas Sidney Kimmel Comprehensive Cancer Center, Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, ...
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Severe Acute Respiratory Syndrome Coronavirus Nonstructural Protein 2 Interacts with a Host Protein Complex Involved in Mitochondrial Biogenesis and Intracellular Signaling
... host proteins for nsp1, 719 for nsp2, 770 for nsp3 UB1-GSM, 618 for nsp3 TM1-Y, 229 for nsp4, and 240 for eYFP. To reduce the list of candidate host proteins, host proteins that were present in the eYFP sample or were ...
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