Arcuate Nucleus
Remodeling of the arcuate nucleus energy balance circuit is inhibited in obese mice
... hypothalamic arcuate nucleus (ARN) energy-balance circuit plays a key role in regulating body ...the arcuate neuronal circuitry in the mouse and reveal the unexpected capacity of diet and leptin ...
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Glucose sensing in the hypothalamic arcuate nucleus: electrophysiological and mathematical studies
... the arcuate nucleus (ARC) are suggested to have higher extracellular glucose levels than other areas in the hypothalamus reflecting their proximal location to the median eminence (ME) where the ...
290
Effects of Hypothalamic Arcuate Nucleus NPY5 Receptor Signaling Pathway on Feeding Regulation in Normal Rats and Obesity Rats
... hypothalamic arcuate nucleus (ARC) in normal rats and obesity rats, and the effect of the NPY5 receptor agonist [D-Trp34] NPY and NPY5 Receptor antagonist CGP-71683 on Food Intake in the normal and obesity ...
6
The electrophysiological and morphological characterisation of aminergic responsive neurones within the rat hypothalamic arcuate nucleus in vitro
... the arcuate nucleus (Arc) are well positioned to detect circulating glucose levels due to its close proximity to the median eminence (ME) where the blood-brain-barrier (BBB) is compromised due to its ...
401
The effect of fasting on the ultrastructure of the hypothalamic arcuate nucleus in young rats
... The arcuate nucleus of the hypothalamus (ARH) is located in the lateral wall of the third ventricle above the median ...the arcuate neurons after treatment with morphine, colchicine, or mercury salts ...
6
Ultrastructural response of arcuate nucleus neurons to fasting in aged rats
... lamic tissue blocks were cut down on a vibratome 1000s (Leica, Germany) into serial coronal slices (500 mm thick). Small tissue specimens containing arcu- ate nucleus were taken bilaterally from the rat brain ...
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The LIM homeobox transcription factor Isl1 plays crucial roles in the development of multiple arcuate nucleus neurons
... hypothalamic arcuate nucleus relay and translate important cues from the periphery into the central nervous ...developing arcuate neurons and plays crucial roles in their fate ...their arcuate ...
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Hypoplasia of Medullary Arcuate Nucleus in Unexpected Late Fetal Death (Stillborn Infants): A Pathologic Study
... solitarii nucleus, nucleus ambiguus, trigem- inal tractus and nucleus, arcuate nucleus, and ventrolat- eral reticular formation and its neurons and parabrachial/ Ko¨lliker-Fuse complex) ...
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Glucokinase activity in the arcuate nucleus regulates glucose intake
... the arcuate nucleus increased food ...the arcuate nucleus of adult male iARC-GK ...reduced arcuate nucleus glucokinase activity by injecting rAAV-ASGK into the arcuate ...
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Transplantable rat glucagonomas cause acute onset of severe anorexia and adipsia despite highly elevated NPY mRNA levels in the hypothalamic arcuate nucleus
... We have isolated a stable, transplantable, and small glu- cagonoma (MSL-G-AN) associated with abrupt onset of se- vere anorexia occurring 2–3 wk after subcutaneous trans- plantation. Before onset of anorexia, food ...
9
Original Article Expression of kisspeptin-GnRH system is down-regulated in hypothalamic arcuate nucleus of male rats with high-fat-diet
... hypothalamic arcuate nucleus GnRH neurons do not exist in LepR without expres- sion of ob-mRNA, and Leptin could not directly act on GnRH neurons ...
9
The arcuate nucleus mediates GLP 1 receptor agonist liraglutide dependent weight loss
... tion. In a series of elegant experiments, Rüttiman et al. showed that, although peripheral administration of exenatide and liraglu- tide was still able to reduce food intake in vagally deafferentated rats, these animals ...
17
Undernutrition Reduces Kisspeptin and Neurokinin B Protein Expression in the Arcuate Nucleus of Young, Male Sheep.
... 10 Females in mammalian species exhibit two distinct populations of KNDy neurons with one being in the rostral part of the hypothalamus and the other being more caudal. In rodents, one population is in the ARC and the ...
79
Metabolic and serotonergic modulation of hypothalamic arcuate nucleus neurones in vitro
... Certain neuronal subtypes within the ARC also express receptors for other substanceswhich are known to be involved in energy homeostasis,for example, leptin, ghrelin, orexin, 5-HT 5-hydr[r] ...
332
Ultrastructural observations on the hypothalamic arcuate nuclei of aged rats in the fasting/refeeding model
... the arcuate region in male rats, whereas van Houten and Brawer [13] observed these structures in nor- mal male rats in the ventrolateral part of the hy- pothalamic ventro-medial nucleus ...of arcuate ...
5
Extrahypothalamic GABAergic nociceptin–expressing neurons regulate AgRP neuron activity to control feeding behavior
... on arcuate POMC and gonadotrophin-releasing hormone neu- rons in electrophysiology studies is documented (26), the actions of nociceptin on AgRP/NPY excitability are less ...in arcuate NPY neurons that was ...
18
Central Nervous System Control of Glucose Homeostasis
... The activation of insulin signaling in hypothalamic arcuate nucleus (ARC) is sufficient to decrease blood glucose levels via the inhibition of hepatic glucose production (GP). This effect is mediated by the ...
8
Association of Leptin Gene Polymorphism in Essential Hypertension.
... NPY which is produced from neurons of the arcuate nucleus acts on PVN and lateral hypothalamus. NPY increases food intake and enhances obesity 125 . These effects result from action on NPY-Y1 & NPY-Y5 ...
190
Review of the role of the nervous system in glucose homoeostasis and future perspectives towards the management of diabetes
... the arcuate nucleus are a key site of this food entrained oscillator where peripheral and possibly other cues are detected independent of visual cues ...
18
What do we understand from clinical and mechanistic studies on acupuncture treatment for hypertension?
... the arcuate nucleus of the hypothalamus, the ventrolateral periaqueductal gray in the midbrain and the nucleus raphe pallidus in the medulla, through inhibiting the activity of premotor sympathetic ...
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