Arginine deiminase
Regulation of the Arginine Deiminase System by ArgR2 Interferes with Arginine Metabolism and Fitness of Streptococcus pneumoniae
... for arginine, and molecular analysis of the pneumococcal genome showed that the gene encoding an arginine-ornithine antiporter (ArcD) is organized in a cluster together with the arcABC genes encod- ing the ...
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Carbohydrate effects on the inducement of the arginine deiminase pathway enzymes in wine lactic acid bacteria : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Microbiology at Massey University
... Carbohydrate Effects on the Inducement of the Arginine Deiminase Pathway Enzymes in Wine Lactic Acid Bacteria.. A Thesis Presented in Partial Fulfillment of the Requirements for the Degr[r] ...
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Carbohydrate effects on the inducement of the arginine deiminase pathway enzymes in wine lactic acid bacteria : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Microbiology at Massey University
... This study has demonstrated the use of non-growing cells in a buffered medium to investigate the effects of glucose and fructose on the enzyme initiation of the arginine deiminase pathwa[r] ...
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Peptidyl arginine deiminase type IV (PADI4) haplotypes interact with shared epitope regardless of anti cyclic citrullinated peptide antibody or erosive joint status in rheumatoid arthritis: a case control study
... peptidyl arginine deiminase type IV gene (PADI4) has been shown in sev- eral studies to be an additional RA susceptibility gene in Asians and in some Caucasian populations ...
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Association of anti peptidyl arginine deiminase antibodies with radiographic severity of rheumatoid arthritis in African Americans
... Rheumatoid arthritis (RA) is an autoimmune inflamma- tory arthritis characterized by the presence of serum autoantibodies, including rheumatoid factor and anti- citrullinated peptide/protein antibodies (ACPAs) [1]. ...
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Pegylated arginine deiminase synergistically increases the cytotoxicity of gemcitabine in human pancreatic cancer
... by arginine through the formation of a activated ternary complex of the argin- ine methyltransferase, PRMT2, the retinoblastoma (RB) protein and ...E2F-1[15]. Arginine also serves as a cellular store for ...
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RNA interference of argininosuccinate synthetase restores sensitivity to recombinant arginine deiminase (rADI) in resistant cancer cells
... Argininosuccinate synthetase (AS), a rate-limiting enzyme in the citrulline-arginine regeneration pathway, has been reported to be the crucial enzyme limiting the response to rADI treatment [3,4]. A human melanoma ...
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Kinetic Characterization of the Protein Arginine Deiminase Family: Mechanistic and Inhibition Studies
... (b) Phase diagram predicted by the molecular field theory for a system of biaxial molecules as a function of the molec- ular biaxiality, λ.. The dashed line shows the anticipated freezin[r] ...
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Association Assessment of Peptidylarginine Deiminase Type 4 (PADI4) rs1748033 polymorphism and susceptibility to rheumatoid arthritis in Gorgan, Northeast of Iran
... Introduction: Rheumatoid arthritis (RA) is a chronic autoimmune disease in which both genetic and environmental factors could be involved. Peptidyl arginine deiminase type IV (PADI4) is an enzyme ...
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New autoantibodies in early rheumatoid arthritis
... peptidyl arginine deiminase 4; PBS: phosphate-buffered saline; PBST: phosphate- buffered saline/Tween; PsA: psoriatic arthritis; RA: rheumatoid arthritis; RF: rheumatoid factor; RNP: ribonucleoprotein; SLE: ...
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Novel drugs that target the metabolic reprogramming in renal cell cancer
... phosphogluconate dehydrogenase; ACAT1, acetyl-coA acetyltransferase; ACC, acetyl-CoA carboxylase; ACLY, ATP citrate lyase; ACO2, aconitase 2; ADI, arginine deiminase; AMPK, AMP-activated[r] ...
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The Reflected-Shifted-Truncated-Gamma Distribution for Negatively Skewed Survival Data with Application to Pediatric Nephrotic Syndrome
... becomes inflamed and develops ulcers leading to abdominal pain, diarrhea, and rectal bleeding. The extent of these symptoms depends on disease severity. The protein arginine deiminase (PAD) family of ...
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Neonatal NET inhibitory factor and related peptides inhibit neutrophil extracellular trap formation
... chromatin studded with histones, granule enzymes, and antimicrobial peptides that are referred to as neutrophil extracellular traps (NETs). NETs capture and contain bacteria, viruses, and other pathogens. Nevertheless, ...
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Quantitative proteome analysis of Merkel cell carcinoma cell lines using SILAC
... In conclusion, this work provides an additional insight in the biology of Merkel cell carcinoma. Multiple dysregu- lated proteins from various pathways were identified. The most abundant proteins were mitoferrin-1, ...
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Predictors of Treatment Adherence in Adolescents with Inflammatory Bowel Disease: The Role of Age, Body Satisfaction and Prospective Memory in Medication and Diet Behavior
... limited. Arginine catabolism is of particular significance in this regard because ...the arginine deiminase (ADI) pathway, the arginine succinyltransferase (AST) pathway, and the ...
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Bacterial and human peptidylarginine deiminases: targets for inhibiting the autoimmune response in rheumatoid arthritis?
... non-peptidyl arginine or arginine derivatives such as arginine deiminase ...free arginine to citrulline, releasing ...of arginine degradation and many pathogenic microorganisms ...
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RESEARCH ARTICLE Association of TP53 codon 72 polymorphism in women suffering from endometriosis from Lahore, Pakistan
... of 20µl polymerase chain reaction (PCR) reaction mixture were: 50ng DNA, 2mM magnesium chloride (MgCl2), 2.5 m Mdeoxynucleotides (dNTPs), 10X PCR buffer, 0.5µM forward and reverse primer and 5U Taq DNA polymerase. The ...
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4-23-2014 12:00 AM The role of the arginine methyltransferase CARM1 in global transcriptional regulation.
... To date, there have been 11 members of the protein arginine methyltransferase (PRMT) family identified [171]. This protein family shares four conserved motifs that constitute the catalytic methyltransferase ...
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Mutants of escherichia coli with abnormal patterns of repression of arginine biosynthetic enzymes : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Microbiology at Massey University
... 37QC Hours "The Effect of Arginine Concentration on Pacesetting of Strain W2-250." Key: 1.* growth of cultures 2 to 6 prdlor to ea:haustion of arginine 3 2.= Control: 30ug/cm arginine on[r] ...
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Reduced glutathione as a physiological co activator in the activation of peptidylarginine deiminase
... PADs on reducing agents is less well understood. Reduction of the active site thiol Cys645/647 is likely to precede attack on the guanidinum carbon of arginine. Thus, the redox balance might be an additional ...
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